WormBase Tree Display for Gene: WBGene00004350
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WBGene00004350 | SMap | S_parent | Sequence | F56B6 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | rgs-7 | Person_evidence | WBPerson330 | |||||
Sequence_name | F56B6.2 | ||||||||
Molecular_name (27) | |||||||||
Other_name | CELE_F56B6.2 | Accession_evidence | NDB | BX284606 | |||||
Public_name | rgs-7 | ||||||||
DB_info | Database | AceView | gene | XE175 | |||||
WormQTL | gene | WBGene00004350 | |||||||
WormFlux | gene | WBGene00004350 | |||||||
NDB | locus_tag | CELE_F56B6.2 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00004350|UniProtKB=Q8WQC0 | |||||||
family | PTHR10845 | ||||||||
NCBI | gene | 180645 | |||||||
RefSeq | protein | NM_001129682.5 | |||||||
NM_001373262.3 | |||||||||
NM_001373261.4 | |||||||||
NM_001374994.1 | |||||||||
NM_001029543.5 | |||||||||
NM_001129681.4 | |||||||||
NM_001373260.4 | |||||||||
NM_001029544.6 | |||||||||
NM_076209.7 | |||||||||
SwissProt | UniProtAcc | Q8WQC0 | |||||||
TrEMBL | UniProtAcc | A0A4V0IJG9 | |||||||
Q1W0R0 | |||||||||
H2KYQ7 | |||||||||
A0A4V0IKM4 | |||||||||
A0A4V0ILX5 | |||||||||
H2KYQ8 | |||||||||
UniProt_GCRP | UniProtAcc | Q8WQC0 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:35 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
2 | 03 Dec 2004 16:13:27 | WBPerson2970 | Event | Acquires_merge | WBGene00018936 | ||||
Acquires_merge | WBGene00018936 | ||||||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | rgs | ||||||||
Allele (194) | |||||||||
Strain | WBStrain00026370 | ||||||||
WBStrain00026372 | |||||||||
WBStrain00032622 | |||||||||
WBStrain00034758 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation | 00021823 | ||||||||
00021824 | |||||||||
00021825 | |||||||||
00085200 | |||||||||
00085201 | |||||||||
Ortholog (38) | |||||||||
Paralog (12) | |||||||||
Structured_description | Concise_description | rgs-7 encodes three isoforms of an atypical regulator of G protein signaling (RGS) protein that contains both a C2 and an RGS domain, and that binds EGL-30 via both domains, similar in organization to mammalian PDZ-RGS3; the RGS domain has GTPase activator protein (GAP) activity in vitro on mammalian G[alphai]3; RGS-7 thus may stably bind EGL-30 at all stages of EGL-30's GTPase cycle, might organize EGL-30 into a stable multiprotein signalling complex (with GTP[gamma]S), and might persistently inhibit EGL-30 when triggered by calcium or phospholipids; rgs-7 has no obvious function in mass RNAi assays | Paper_evidence | WBPaper00005654 | |||||
WBPaper00005958 | |||||||||
WBPaper00013066 | |||||||||
Curator_confirmed | WBPerson567 | ||||||||
Date_last_updated | 18 Jun 2007 00:00:00 | ||||||||
Automated_description | Enables GTPase activator activity. Predicted to be involved in negative regulation of signal transduction. Located in cell cortex. Is an ortholog of several human genes including RGS1 (regulator of G protein signaling 1); RGS13 (regulator of G protein signaling 13); and RGS4 (regulator of G protein signaling 4). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | F56B6.2a | |||||||
F56B6.2b | |||||||||
F56B6.2c | |||||||||
F56B6.2e | |||||||||
F56B6.2f | |||||||||
F56B6.2g | |||||||||
F56B6.2h | |||||||||
F56B6.2i | |||||||||
F56B6.2j | |||||||||
Corresponding_CDS_history | F56B6.2d:wp271 | ||||||||
Corresponding_transcript | F56B6.2a.1 | ||||||||
F56B6.2b.1 | |||||||||
F56B6.2c.1 | |||||||||
F56B6.2e.1 | |||||||||
F56B6.2f.1 | |||||||||
F56B6.2g.1 | |||||||||
F56B6.2h.1 | |||||||||
F56B6.2i.1 | |||||||||
F56B6.2j.1 | |||||||||
Other_sequence | PP01804 | ||||||||
Acan_isotig02910 | |||||||||
EX546327.1 | |||||||||
Oden_isotig23989 | |||||||||
Hbac_isotig04349 | |||||||||
EX566353.1 | |||||||||
Acan_isotig02911 | |||||||||
EY465298.1 | |||||||||
Acan_isotig05414 | |||||||||
EY465766.1 | |||||||||
Dviv_isotig26608 | |||||||||
EX912667.1 | |||||||||
JI166735.1 | |||||||||
Acan_isotig05415 | |||||||||
EY466704.1 | |||||||||
EX553851.1 | |||||||||
ACC23944_1 | |||||||||
HBC26737_1 | |||||||||
PPC00790_1 | |||||||||
ACC34384_1 | |||||||||
ACC11150_1 | |||||||||
Associated_feature (27) | |||||||||
Experimental_info | RNAi_result | WBRNAi00048645 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00048644 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00032932 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00015785 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr3108 | ||||||||
Expr1025711 | |||||||||
Expr1032168 | |||||||||
Expr1152407 | |||||||||
Expr1200208 | |||||||||
Expr2015330 | |||||||||
Expr2033564 | |||||||||
Drives_construct (2) | |||||||||
Construct_product | WBCnstr00011142 | ||||||||
WBCnstr00035547 | |||||||||
Microarray_results (53) | |||||||||
Expression_cluster (147) | |||||||||
Interaction | WBInteraction000523424 | ||||||||
WBInteraction000523425 | |||||||||
WBInteraction000539245 | |||||||||
WBInteraction000543714 | |||||||||
WBInteraction000544009 | |||||||||
WBInteraction000550677 | |||||||||
WBInteraction000550678 | |||||||||
WBInteraction000555666 | |||||||||
WBInteraction000555672 | |||||||||
WBInteraction000556608 | |||||||||
WBInteraction000582380 | |||||||||
WBProcess | WBbiopr:00000017 | ||||||||
Map_info | Map | X | Position | -10.1117 | Error | 0.033929 | |||
Positive | Positive_clone | F56B6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Mapping_data | Multi_point | 5042 | |||||||
Pseudo_map_position | |||||||||
Reference (17) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |