WormBase Tree Display for Gene: WBGene00004387
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| WBGene00004387 | SMap | S_parent | Sequence | R07E5 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | rnp-4 | Person_evidence | WBPerson421 | |||||
| Sequence_name | R07E5.14 | ||||||||
| Molecular_name | R07E5.14 | ||||||||
| R07E5.14.1 | |||||||||
| CE01044 | |||||||||
| R07E5.14.2 | |||||||||
| Other_name | Ce-Y14 | Paper_evidence | WBPaper00006367 | ||||||
| CELE_R07E5.14 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | rnp-4 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:35 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | rnp | ||||||||
| Allele | WBVar00821653 | ||||||||
| WBVar00821654 | |||||||||
| WBVar00821655 | |||||||||
| WBVar01578856 | |||||||||
| WBVar00091906 | |||||||||
| WBVar01644084 | |||||||||
| WBVar01837450 | |||||||||
| WBVar01644085 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (27) | |||||||||
| Contained_in_operon | CEOP3184 | ||||||||
| Ortholog (29) | |||||||||
| Structured_description | Concise_description | rnp-4 encodes a putative member of the exon-exon junction complex, orthologous to Y14 in S. cerevisiae and TSUNAGI in D. melanogaster; RNP-4 is required for embryonic viability, fertility, vulval development, and cuticular integrity; however, rnp-4(RNAi) animals show no accumulation of poly(A)+ mRNA in their nuclei, indicating that RNP-4 is dispensable for mRNA export. | Paper_evidence | WBPaper00005654 | |||||
| WBPaper00005960 | |||||||||
| Person_evidence | WBPerson71 | ||||||||
| Curator_confirmed | WBPerson13481 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Enables U2 snRNA binding activity; mRNA binding activity; and pre-mRNA binding activity. Involved in several processes, including feminization of hermaphroditic germ-line; nuclear mRNA surveillance; and positive regulation of oogenesis. Located in cytoplasm and nucleus. Expressed in several structures, including germ line. Human ortholog(s) of this gene implicated in thrombocytopenia-absent radius syndrome. Is an ortholog of human RBM8A (RNA binding motif protein 8A). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:14699 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9905) | ||||
| Molecular_info | Corresponding_CDS | R07E5.14 | |||||||
| Corresponding_transcript | R07E5.14.1 | ||||||||
| R07E5.14.2 | |||||||||
| Other_sequence (81) | |||||||||
| Associated_feature | WBsf224732 | ||||||||
| WBsf224733 | |||||||||
| WBsf224734 | |||||||||
| Experimental_info | RNAi_result (21) | ||||||||
| Expr_pattern | Expr2895 | ||||||||
| Expr1025575 | |||||||||
| Expr1032198 | |||||||||
| Expr1155167 | |||||||||
| Expr2015393 | |||||||||
| Expr2033627 | |||||||||
| Drives_construct | WBCnstr00000321 | ||||||||
| WBCnstr00035519 | |||||||||
| Construct_product | WBCnstr00035519 | ||||||||
| Microarray_results (28) | |||||||||
| Expression_cluster (126) | |||||||||
| Interaction (117) | |||||||||
| Map_info | Map | III | Position | -3.17654 | Error | 0.000438 | |||
| Positive | Positive_clone | K02F3 | |||||||
| R07E5 | Inferred_automatically | From CDS info | |||||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference (13) | |||||||||
| Remark | rnp-4 was mistakenly connected to K02F3.11 | CGC_data_submission | |||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
