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WormBase Tree Display for Gene: WBGene00004950

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Name Class

WBGene00004950SMapS_parentSequenceF40E10
IdentityVersion1
NameCGC_namesox-3Person_evidenceWBPerson490
Sequence_nameF40E10.2
Molecular_nameF40E10.2
F40E10.2.1
CE05838
F40E10.2.2
Other_nameCELE_F40E10.2Accession_evidenceNDBBX284606
Public_namesox-3
DB_infoDatabaseAceViewgeneXP308
WormQTLgeneWBGene00004950
WormFluxgeneWBGene00004950
NDBlocus_tagCELE_F40E10.2
PanthergeneCAEEL|WormBase=WBGene00004950|UniProtKB=Q20201
familyPTHR10270
NCBIgene185534
RefSeqproteinNM_078038.6
SwissProtUniProtAccQ20201
TREEFAMTREEFAM_IDTF351735
UniProt_GCRPUniProtAccQ20201
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:37WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classsox
Reference_alleleWBVar00239209
Allele (58)
StrainWBStrain00028921
WBStrain00035630
WBStrain00055553
RNASeq_FPKM (74)
GO_annotation (11)
Ortholog (37)
ParalogWBGene00004771Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00004949Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00015716Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00001182Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00001325Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionsox-3 encodes a putative HMG-box transcription factor orthologous to human SOX1 (OMIM:602148), SOX2 (OMIM:184429, mutated in syndromic anophthalmia), and SOX3 (OMIM:313430, mutated in hypopituitarism), and paralogous to SOX-2; SOX-3 is expressed in larval and adult pharynx, intestine, renal gland cells, and neurons.Paper_evidenceWBPaper00006525
WBPaper00031006
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated17 Jun 2011 00:00:00
Automated_descriptionPredicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in neuron differentiation. Predicted to be located in nucleus. Expressed in head neurons and rectal epithelial cell. Is an ortholog of human SOX14 (SRY-box transcription factor 14) and SOX21 (SRY-box transcription factor 21).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF40E10.2
Corresponding_transcriptF40E10.2.1
F40E10.2.2
Other_sequence (33)
Associated_featureWBsf978600
WBsf1007975
WBsf1007976
WBsf1024443
Transcription_factorWBTranscriptionFactor000205
Experimental_infoRNAi_resultWBRNAi00032017Inferred_automaticallyRNAi_primary
WBRNAi00107409Inferred_automaticallyRNAi_primary
WBRNAi00014643Inferred_automaticallyRNAi_primary
WBRNAi00046838Inferred_automaticallyRNAi_primary
Expr_patternChronogram477
Expr6007
Expr12602
Expr1022365
Expr1032464
Expr1150708
Expr2016014
Expr2034249
Drives_constructWBCnstr00003229
WBCnstr00035309
Construct_productWBCnstr00020693
WBCnstr00035309
Microarray_results (18)
Expression_cluster (114)
Interaction (37)
Map_infoMapXPosition19.9403Error0.059154
PositivePositive_cloneF40E10Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point5528
4664
Pseudo_map_position
ReferenceWBPaper00015364
WBPaper00017584
WBPaper00038491
WBPaper00039222
WBPaper00040964
WBPaper00047042
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene