WormBase Tree Display for Gene: WBGene00005020
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| WBGene00005020 | Evidence | Paper_evidence | WBPaper00005800 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | Y110A2AL | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | sqv-2 | Person_evidence | WBPerson268 | |||||
| Sequence_name | Y110A2AL.14 | ||||||||
| Molecular_name | Y110A2AL.14 | ||||||||
| Y110A2AL.14.1 | |||||||||
| CE25190 | |||||||||
| Other_name | CELE_Y110A2AL.14 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | sqv-2 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:37 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | sqv | ||||||||
| Allele (137) | |||||||||
| Legacy_information | [Herman T] sqv for squashed vulva. morphology of L4 vulva abnormal (invagination considerably reduced). hermaphrodites self-sterile. n2826, n2821 somewhat fertile. | ||||||||
| [C.elegansII] n2826 : morphology of L4 vulva abnormal (invagination considerably reduced); hermaphrodites self-sterile. OA4: n2821 (somewhat fertile), n3037, n3038,n2826, n2821. [MT] | |||||||||
| Strain | WBStrain00027289 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (24) | |||||||||
| Contained_in_operon | CEOP2072 | ||||||||
| CEOP2074 | |||||||||
| Ortholog (31) | |||||||||
| Paralog (18) | |||||||||
| Structured_description | Concise_description | sqv-2 encodes a glycosaminoglycan galactosyltransferase II, biochemically active in vitro, that is required for cytokinesis of one-cell embryos and for vulval morphogenesis; the common requirement for SQV-2 in both cytokinesis and morphogenesis may be to promote filling an extracellular space with hygroscopic proteoglycans (either in the eggshell, or underneath the L4 cuticle), which in turn may cause the space to fill with fluid. | Paper_evidence | WBPaper00003405 | |||||
| WBPaper00004509 | |||||||||
| WBPaper00005800 | |||||||||
| WBPaper00005867 | |||||||||
| WBPaper00005868 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Enables galactosylxylosylprotein 3-beta-galactosyltransferase activity. Involved in several processes, including egg-laying behavior; glycosaminoglycan biosynthetic process; and vulval development. Located in Golgi apparatus. Expressed in intestine. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome spondylodysplastic type 2 and spondyloepimetaphyseal dysplasia with joint laxity type 1. Is an ortholog of human B3GALT6 (beta-1,3-galactosyltransferase 6). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0112198 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:17978) | ||||
| DOID:0050802 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:17978) | ||||||
| Molecular_info | Corresponding_CDS | Y110A2AL.14 | |||||||
| Corresponding_transcript | Y110A2AL.14.1 | ||||||||
| Other_sequence (29) | |||||||||
| Associated_feature | WBsf665414 | ||||||||
| WBsf981169 | |||||||||
| WBsf987093 | |||||||||
| WBsf987094 | |||||||||
| WBsf222812 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00115278 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00061137 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00055298 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00019855 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00082826 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00001214 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00061138 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00036540 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr3521 | ||||||||
| Expr3522 | |||||||||
| Expr1022923 | |||||||||
| Expr1032503 | |||||||||
| Expr1158835 | |||||||||
| Expr2016120 | |||||||||
| Expr2034355 | |||||||||
| Drives_construct | WBCnstr00011447 | ||||||||
| Construct_product | WBCnstr00011447 | ||||||||
| Antibody | WBAntibody00000873 | ||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (95) | |||||||||
| Interaction | WBInteraction000134117 | ||||||||
| Map_info | Map | II | Position | -9.48977 | Error | 0.058265 | |||
| Positive | Positive_clone | Y110A2AL | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 3136 | |||||||
| 3137 | |||||||||
| 4329 | |||||||||
| Reference (15) | |||||||||
| Method | Gene |
