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WormBase Tree Display for Gene: WBGene00005663

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Name Class

WBGene00005663SMapS_parentSequenceC47E12
IdentityVersion2
NameCGC_namesars-1Person_evidenceWBPerson36
WBPerson10953
Sequence_nameC47E12.1
Molecular_nameC47E12.1
C47E12.1.1
CE05445
C47E12.1.2
Other_namesrs-2
CELE_C47E12.1Accession_evidenceNDBBX284604
Public_namesars-1
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:38WBPerson1971EventImportedInitial conversion from geneace
229 Jan 2010 14:16:16WBPerson2970Name_changeCGC_namesars-1
Other_namesrs-2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classsars
Allele (18)
RNASeq_FPKM (74)
GO_annotation (24)
Ortholog (39)
ParalogWBGene00005662Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionsrs-2 encodes a predicted cytoplasmic seryl-tRNA synthetase (SerRS), a class II aminoacyl-tRNA synthetase that catalyzes the attachment of serine to its cognate tRNA and is thus required for protein biosynthesis; in C. elegans, SRS-2 activity is required for embryonic and germline development and normal postembryonic growth rates.Paper_evidenceWBPaper00004424
WBPaper00005654
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable serine-tRNA ligase activity and tRNA binding activity. Involved in translation. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in intellectual disability and prostate carcinoma. Is an ortholog of human SARS1 (seryl-tRNA synthetase 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:10286Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10537)
DOID:1059Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10537)
Molecular_infoCorresponding_CDSC47E12.1
Corresponding_transcriptC47E12.1.1
C47E12.1.2
Other_sequence (122)
Associated_featureWBsf646273
WBsf660544
WBsf981809
WBsf997533
WBsf228911
WBsf228912
WBsf228913
Experimental_infoRNAi_resultWBRNAi00096888Inferred_automaticallyRNAi_primary
WBRNAi00008527Inferred_automaticallyRNAi_primary
WBRNAi00024843Inferred_automaticallyRNAi_primary
WBRNAi00042672Inferred_automaticallyRNAi_primary
WBRNAi00096949Inferred_automaticallyRNAi_primary
WBRNAi00064407Inferred_automaticallyRNAi_primary
WBRNAi00029907Inferred_automaticallyRNAi_primary
Expr_patternExpr1023660
Expr1032526
Expr1146659
Expr2015597
Expr2033832
Drives_constructWBCnstr00037919
Construct_productWBCnstr00037919
Microarray_results (26)
Expression_cluster (141)
Interaction (172)
Map_infoMapIVPosition4.46424Error0.000783
PositivePositive_cloneC47E12Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00026640
WBPaper00035429
WBPaper00038491
WBPaper00041771
WBPaper00049828
WBPaper00055090
WBPaper00061547
Remarkdl1 : probably cytoplasmic
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene