WormBase Tree Display for Gene: WBGene00006435
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WBGene00006435 | Evidence | CGC_data_submission | |||||||
---|---|---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | F25G6 | ||||||
Identity | Version | 2 | |||||||
Name | CGC_name | stdh-4 | |||||||
Sequence_name | F25G6.5 | ||||||||
Molecular_name | F25G6.5a | ||||||||
F25G6.5a.1 | |||||||||
CE47137 | |||||||||
F25G6.5b | |||||||||
CE52769 | |||||||||
F25G6.5b.1 | |||||||||
Other_name | tag-57 | Person_evidence | WBPerson201 | ||||||
CELE_F25G6.5 | Accession_evidence | NDB | BX284605 | ||||||
Public_name | stdh-4 | ||||||||
DB_info | Database (13) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:40 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
2 | 27 Nov 2007 15:17:26 | WBPerson2970 | Name_change | CGC_name | stdh-4 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | stdh | ||||||||
Allele (28) | |||||||||
Strain | WBStrain00002288 | ||||||||
WBStrain00035663 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation | 00003241 | ||||||||
00003242 | |||||||||
00003243 | |||||||||
00003244 | |||||||||
00028932 | |||||||||
00028933 | |||||||||
Ortholog (67) | |||||||||
Paralog (38) | |||||||||
Structured_description | Concise_description | stdh-4 encodes a putative steroid dehydrogenase expressed in larval and adult pharynx; STDH-4 is orthologous to human HSD17B3 (OMIM:605573, mutated in pseudohermaphroditism), HSD17B12 (OMIM:609574), and HSDL1, and paralogous to LET-767 and STDH-1/-3; STDH-4 has no obvious function in mass RNAi assays. | Paper_evidence | WBPaper00006204 | |||||
WBPaper00006525 | |||||||||
WBPaper00031006 | |||||||||
Curator_confirmed | WBPerson567 | ||||||||
Date_last_updated | 26 Nov 2007 00:00:00 | ||||||||
Automated_description | Predicted to enable oxidoreductase activity. Predicted to be involved in fatty acid elongation. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in 17-beta hydroxysteroid dehydrogenase 3 deficiency and Alzheimer's disease. Is an ortholog of human HSD17B12 (hydroxysteroid 17-beta dehydrogenase 12). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:10652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:5212) | ||||
DOID:1923 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:5212) | ||||||
DOID:0112248 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:5212) | ||||||
Molecular_info | Corresponding_CDS | F25G6.5a | |||||||
F25G6.5b | |||||||||
Corresponding_CDS_history | F25G6.5:wp230 | ||||||||
Corresponding_transcript | F25G6.5a.1 | ||||||||
F25G6.5b.1 | |||||||||
Other_sequence (11) | |||||||||
Associated_feature | WBsf718354 | ||||||||
WBsf1000690 | |||||||||
WBsf1000691 | |||||||||
WBsf1000692 | |||||||||
WBsf1020052 | |||||||||
Experimental_info | RNAi_result | WBRNAi00045527 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00013885 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Chronogram1449 | ||||||||
Chronogram1662 | |||||||||
Expr5858 | |||||||||
Expr1012380 | |||||||||
Expr1149442 | |||||||||
Expr2016959 | |||||||||
Expr2035107 | |||||||||
Drives_construct | WBCnstr00002988 | ||||||||
WBCnstr00004487 | |||||||||
WBCnstr00037909 | |||||||||
Construct_product | WBCnstr00037909 | ||||||||
Microarray_results (18) | |||||||||
Expression_cluster (40) | |||||||||
Interaction (90) | |||||||||
Map_info | Map | V | Position | 1.4451 | Error | 0.002002 | |||
Positive | Positive_clone | F25G6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Mapping_data | Multi_point | 4869 | |||||||
Pseudo_map_position | |||||||||
Reference | WBPaper00018598 | ||||||||
WBPaper00038491 | |||||||||
WBPaper00042257 | |||||||||
WBPaper00055090 | |||||||||
Remark | Gene name created from parsing 'genotype' field from CGC strain information | CGC_data_submission | |||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
Method | Gene |