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WormBase Tree Display for Gene: WBGene00006435

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Name Class

WBGene00006435EvidenceCGC_data_submission
SMapS_parentSequenceF25G6
IdentityVersion2
NameCGC_namestdh-4
Sequence_nameF25G6.5
Molecular_nameF25G6.5a
F25G6.5a.1
CE47137
F25G6.5b
CE52769
F25G6.5b.1
Other_nametag-57Person_evidenceWBPerson201
CELE_F25G6.5Accession_evidenceNDBBX284605
Public_namestdh-4
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:40WBPerson1971EventImportedInitial conversion from geneace
227 Nov 2007 15:17:26WBPerson2970Name_changeCGC_namestdh-4
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classstdh
Allele (28)
StrainWBStrain00002288
WBStrain00035663
RNASeq_FPKM (74)
GO_annotation00003241
00003242
00003243
00003244
00028932
00028933
Ortholog (67)
Paralog (38)
Structured_descriptionConcise_descriptionstdh-4 encodes a putative steroid dehydrogenase expressed in larval and adult pharynx; STDH-4 is orthologous to human HSD17B3 (OMIM:605573, mutated in pseudohermaphroditism), HSD17B12 (OMIM:609574), and HSDL1, and paralogous to LET-767 and STDH-1/-3; STDH-4 has no obvious function in mass RNAi assays.Paper_evidenceWBPaper00006204
WBPaper00006525
WBPaper00031006
Curator_confirmedWBPerson567
Date_last_updated26 Nov 2007 00:00:00
Automated_descriptionPredicted to enable oxidoreductase activity. Predicted to be involved in fatty acid elongation. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in 17-beta hydroxysteroid dehydrogenase 3 deficiency and Alzheimer's disease. Is an ortholog of human HSD17B12 (hydroxysteroid 17-beta dehydrogenase 12).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:10652Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5212)
DOID:1923Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5212)
DOID:0112248Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5212)
Molecular_infoCorresponding_CDSF25G6.5a
F25G6.5b
Corresponding_CDS_historyF25G6.5:wp230
Corresponding_transcriptF25G6.5a.1
F25G6.5b.1
Other_sequence (11)
Associated_featureWBsf718354
WBsf1000690
WBsf1000691
WBsf1000692
WBsf1020052
Experimental_infoRNAi_resultWBRNAi00045527Inferred_automaticallyRNAi_primary
WBRNAi00013885Inferred_automaticallyRNAi_primary
Expr_patternChronogram1449
Chronogram1662
Expr5858
Expr1012380
Expr1149442
Expr2016959
Expr2035107
Drives_constructWBCnstr00002988
WBCnstr00004487
WBCnstr00037909
Construct_productWBCnstr00037909
Microarray_results (18)
Expression_cluster (40)
Interaction (90)
Map_infoMapVPosition1.4451Error0.002002
PositivePositive_cloneF25G6Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4869
Pseudo_map_position
ReferenceWBPaper00018598
WBPaper00038491
WBPaper00042257
WBPaper00055090
RemarkGene name created from parsing 'genotype' field from CGC strain informationCGC_data_submission
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene