WormBase Tree Display for Gene: WBGene00006449
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| WBGene00006449 | SMap | S_parent | Sequence | CHROMOSOME_III | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | alg-4 | Paper_evidence | WBPaper00035890 | |||||
| Person_evidence | WBPerson419 | ||||||||
| Sequence_name | ZK757.3 | ||||||||
| Molecular_name | ZK757.3a | ||||||||
| ZK757.3a.1 | |||||||||
| CE01117 | |||||||||
| ZK757.3b | |||||||||
| CE24737 | |||||||||
| ZK757.3c | |||||||||
| CE24738 | |||||||||
| ZK757.3a.2 | |||||||||
| ZK757.3b.1 | |||||||||
| ZK757.3c.1 | |||||||||
| Other_name | tag-76 | Person_evidence | WBPerson201 | ||||||
| CELE_ZK757.3 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | alg-4 | ||||||||
| DB_info | Database | AceView | gene | 3K978 | |||||
| WormQTL | gene | WBGene00006449 | |||||||
| WormFlux | gene | WBGene00006449 | |||||||
| NDB | locus_tag | CELE_ZK757.3 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00006449|UniProtKB=P34681 | |||||||
| family | PTHR22891 | ||||||||
| NCBI | gene | 176400 | |||||||
| RefSeq | protein | NM_066791.6 | |||||||
| NM_066790.5 | |||||||||
| NM_066792.4 | |||||||||
| SwissProt | UniProtAcc | P34681 | |||||||
| TREEFAM | TREEFAM_ID | TF101510 | |||||||
| UniProt_GCRP | UniProtAcc | P34681 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:40 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 23 Dec 2013 11:02:34 | WBPerson2970 | Name_change | CGC_name | alg-4 | ||||
| Other_name | tag-76 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | alg | ||||||||
| Allele (54) | |||||||||
| Possibly_affected_by | WBVar02158851 | ||||||||
| Strain | WBStrain00031783 | ||||||||
| WBStrain00035704 | |||||||||
| WBStrain00040479 | |||||||||
| WBStrain00054823 | |||||||||
| WBStrain00054838 | |||||||||
| In_cluster | conserved_RDE-1_cluster | ||||||||
| conserved_miRNA_siRNA_cluster | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00043933 | ||||||||
| 00043934 | |||||||||
| 00043935 | |||||||||
| 00043936 | |||||||||
| 00043937 | |||||||||
| 00043938 | |||||||||
| 00114090 | |||||||||
| 00114091 | |||||||||
| Ortholog (49) | |||||||||
| Paralog (22) | |||||||||
| Structured_description | Concise_description | alg-4 encodes an Argonaute (AGO) protein that is a member of the AGO clade of Argonaute small RNA-binding proteins; together with its paralog, alg-3, alg-4 is required for normal brood sizes at elevated temperatures, specifically for the process of spermiogenesis in which spermatids are converted to mobile ameboid sperm; alg-3/4 is also required for accumulation of male germline-specific 26G-RNAs, suggesting that alg-3/4 mediate thermotolerant fertility via a 26G-RNA-mediated pathway. | Paper_evidence | WBPaper00035890 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 11 Feb 2010 00:00:00 | ||||||||
| Automated_description | Predicted to enable RNA endonuclease activity and single-stranded RNA binding activity. Involved in spermatogenesis. Predicted to be located in P granule. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | ZK757.3a | |||||||
| ZK757.3b | |||||||||
| ZK757.3c | |||||||||
| Corresponding_transcript | ZK757.3a.1 | ||||||||
| ZK757.3a.2 | |||||||||
| ZK757.3b.1 | |||||||||
| ZK757.3c.1 | |||||||||
| Other_sequence (59) | |||||||||
| Associated_feature | WBsf993838 | ||||||||
| WBsf993839 | |||||||||
| WBsf227384 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00024280 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00022160 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00006098 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00024193 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00023908 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00059707 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00038437 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00023393 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr16404 | ||||||||
| Expr1163123 | |||||||||
| Expr2009291 | |||||||||
| Expr2027528 | |||||||||
| Drives_construct | WBCnstr00037904 | ||||||||
| Construct_product | WBCnstr00037904 | ||||||||
| Regulate_expr_cluster | WBPaper00044616:alg-3-4_downregulated_gene | ||||||||
| WBPaper00044616:alg-3-4_downregulated_protein | |||||||||
| WBPaper00044616:alg-3-4_upregulated_gene | |||||||||
| WBPaper00044616:alg-3-4_upregulated_protein | |||||||||
| Microarray_results (34) | |||||||||
| Expression_cluster (213) | |||||||||
| Interaction (17) | |||||||||
| Map_info | Map | III | Position | 1.14143 | Error | 0.003871 | |||
| Positive | Positive_clone | ZK757 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (25) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
