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WormBase Tree Display for Gene: WBGene00006475

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Name Class

WBGene00006475SMapS_parentSequenceM03F4
IdentityVersion2
NameCGC_nametyra-3Person_evidenceWBPerson3043
WBPerson2375
Sequence_nameM03F4.3
Molecular_nameM03F4.3a
M03F4.3a.1
CE31203
M03F4.3b
CE12360
M03F4.3c
CE39602
M03F4.3b.1
M03F4.3c.1
Other_nametag-126Person_evidenceWBPerson201
CELE_M03F4.3Accession_evidenceNDBBX284606
Public_nametyra-3
DB_infoDatabaseAceViewgeneXF573
WormQTLgeneWBGene00006475
WormFluxgeneWBGene00006475
NDBlocus_tagCELE_M03F4.3
PanthergeneCAEEL|WormBase=WBGene00006475|UniProtKB=Q7JNP9
familyPTHR24247
NCBIgene187427
RefSeqproteinNM_001047810.5
NM_001029634.3
NM_001029633.5
TREEFAMTREEFAM_IDTF351748
TrEMBLUniProtAccQ2L6V9
Q23013
Q7JNP9
UniProt_GCRPUniProtAccQ7JNP9
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:40WBPerson1971EventImportedInitial conversion from geneace
203 Nov 2006 15:23:23WBPerson1847Name_changeCGC_nametyra-3
Other_nametag-126
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classtyra
Allele (98)
StrainWBStrain00001190
WBStrain00035522
WBStrain00005317
Component_of_genotypeWBGenotype00000147
RNASeq_FPKM (74)
GO_annotation (19)
Ortholog (29)
Paralog (20)
Structured_descriptionConcise_descriptiontyra-3 encodes a homolog of octopamine or tyramine receptors that isexpressed in head neurons (anterior deirid and cephalic sensilla), tailneurons, and vulva; TYRA-3 is required for normal inhibition ofmovement by 5-HT, with tyra-3(RNAi) animals being hyperactive;heterologously expressed TYRA-3 has no effect on adenylate cyclaseactivity.Paper_evidenceWBPaper00024527
WBPaper00028762
Curator_confirmedWBPerson567
Date_last_updated20 Dec 2006 00:00:00
Automated_descriptionPredicted to enable G protein-coupled serotonin receptor activity; neurotransmitter receptor activity; and octopamine receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger and chemical synaptic transmission. Predicted to be located in dendrite. Expressed in SDQ; gonad; head neurons; and vulva. Used to study Parkinson's disease.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:14330Homo sapiensPaper_evidenceWBPaper00061246
Curator_confirmedWBPerson324
Date_last_updated15 Feb 2023 00:00:00
Models_disease_assertedWBDOannot00001373
Molecular_infoCorresponding_CDSM03F4.3a
M03F4.3b
M03F4.3c
Corresponding_transcriptM03F4.3a.1
M03F4.3b.1
M03F4.3c.1
Other_sequence (24)
Associated_feature (13)
Experimental_infoRNAi_result (12)
Expr_pattern (14)
Drives_construct (14)
Construct_productWBCnstr00009423
WBCnstr00009424
WBCnstr00009425
WBCnstr00009426
WBCnstr00020384
WBCnstr00034342
WBCnstr00041563
WBCnstr00041564
Microarray_results (27)
Expression_cluster (110)
Interaction (40)
Anatomy_functionWBbtf0436
WBbtf0437
WBbtf0438
WBbtf0439
Map_infoMapXPosition-6.20064Error0.003957
PositivePositive_cloneM03F4Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4925
5635
Pseudo_map_position
Reference (34)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene