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WormBase Tree Display for Gene: WBGene00006676

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Name Class

WBGene00006676EvidencePerson_evidenceWBPerson655
SMapS_parentSequenceF19D8
IdentityVersion1
NameCGC_nametwk-23Person_evidenceWBPerson655
Sequence_nameF19D8.1
Molecular_nameF19D8.1a
F19D8.1a.1
CE47571
F19D8.1b
CE47637
F19D8.1c
CE47671
F19D8.1b.1
F19D8.1c.1
Other_nametwk-6Person_evidenceWBPerson655
CELE_F19D8.1Accession_evidenceNDBBX284606
Public_nametwk-23
DB_infoDatabaseAceViewgeneXO436
WormQTLgeneWBGene00006676
WormFluxgeneWBGene00006676
NDBlocus_tagCELE_F19D8.1
PanthergeneCAEEL|WormBase=WBGene00006676|UniProtKB=I2HAD3
familyPTHR11003
NCBIgene192071
RefSeqproteinNM_001270300.3
NM_001270302.3
NM_001270301.4
TrEMBLUniProtAccI2HAD3
I2HAD2
I2HAD1
UniProt_GCRPUniProtAccI2HAD3
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:41WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classtwk
Allele (105)
RNASeq_FPKM (74)
GO_annotation (11)
Ortholog (39)
Paralog (47)
Structured_descriptionConcise_descriptiontwk-23 encodes one of 44 C. elegans TWK (two-P domain K+) potassium channel subunits that contain two pore-forming domains and four transmembrane domains; the precise role of TWK-23 in C. elegans development and/or behavior is not yet known, however TWK-23 may function redundantly with other TWK channels; TWK-23 is expressed in neurons, muscle, the posterior intestine, and diffusely in many other tissues.Paper_evidenceWBPaper00004644
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Expressed in intestine; muscle cell; and neurons. Is an ortholog of human KCNK2 (potassium two pore domain channel subfamily K member 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF19D8.1a
F19D8.1b
F19D8.1c
Corresponding_CDS_historyF19D8.1:wp231
Corresponding_transcriptF19D8.1a.1
F19D8.1b.1
F19D8.1c.1
Other_sequenceDAC00342_1
JI235292.1
DA02518
Associated_featureWBsf671216
WBsf1007735
WBsf1007736
WBsf1024303
WBsf1024304
WBsf1024305
Experimental_infoRNAi_resultWBRNAi00045016Inferred_automaticallyRNAi_primary
Expr_patternExpr1372
Expr1012881
Expr1148980
Expr2017650
Expr2035790
Drives_constructWBCnstr00010246
WBCnstr00034221
Construct_productWBCnstr00010246
WBCnstr00034221
Microarray_results (20)
Expression_cluster (73)
Interaction (96)
Map_infoMapXPosition14.994Error0.019321
PositivePositive_cloneF19D8Inferred_automaticallyFrom sequence, transcript, pseudogene data
F34D6
Pseudo_map_position
ReferenceWBPaper00006402
WBPaper00026748
WBPaper00038491
WBPaper00055090
Remarktwk-23 was connected to F34D6.3Person_evidenceWBPerson655
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene