WormBase Tree Display for Gene: WBGene00006698

WBGene00006698 Evidence: Person_evidence: WBPerson71
  SMap: S_parent: Sequence: Y116A8C
  Identity: Version: 1
    Name: CGC_name: uaf-2 Person_evidence: WBPerson71
      Sequence_name: Y116A8C.35
      Molecular_name: Y116A8C.35a
        Y116A8C.35a.1
        CE23341
        Y116A8C.35b
        CE50583
        Y116A8C.35a.2
        Y116A8C.35b.1
      Other_name: CELE_Y116A8C.35 Accession_evidence: NDB BX284604
      Public_name: uaf-2
    DB_info: Database: AceView gene 4S62
        WormQTL gene WBGene00006698
        WormFlux gene WBGene00006698
        NDB locus_tag CELE_Y116A8C.35
        Panther gene CAEEL|EnsemblGenome=WBGene00006698|UniProtKB=Q9U2U0
          family PTHR12620
        NCBI gene 178489
        RefSeq protein NM_001313048.3
            NM_070635.6
        TrEMBL UniProtAcc Q9U2U0
            A0A0K3AXF6
        UniProt_GCRP UniProtAcc Q9U2U0
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:41 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: uaf
    Allele (47)
    Strain: WBStrain00037620
      WBStrain00051006
    RNASeq_FPKM (74)
    GO_annotation (13)
    Contained_in_operon: CEOP4596
    Ortholog (38)
    Structured_description: Concise_description: uaf-2 encodes an essential U2AF35 homolog clustered in an operon with cyp-13 (RRM/cyclophilin); UAF-2's sequence is somewhat atypical for U2AF proteins (it lacks an identifiable N-terminal RNA-binding RS domain, while having an glycine-rich C-terminal region). Paper_evidence: WBPaper00003463
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Enables pre-mRNA 3'-splice site binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be part of U2AF complex and spliceosomal complex. Is an ortholog of human U2AF1 (U2 small nuclear RNA auxiliary factor 1) and U2AF1L4 (U2 small nuclear RNA auxiliary factor 1 like 4). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: Y116A8C.35a
      Y116A8C.35b
    Corresponding_transcript: Y116A8C.35a.1
      Y116A8C.35a.2
      Y116A8C.35b.1
    Other_sequence (126)
    Associated_feature: WBsf652414
      WBsf981870
      WBsf998975
      WBsf998976
      WBsf998977
      WBsf1018949
      WBsf1018950
      WBsf1018951
    Gene_product_binds: WBsf034320
    Transcription_factor: WBTranscriptionFactor000121
  Experimental_info: RNAi_result (28)
    Expr_pattern: Expr6892
      Expr1019162
      Expr1032781
      Expr1158964
      Expr2017694
      Expr2035832
    Drives_construct: WBCnstr00004191
    Microarray_results (17)
    Expression_cluster: WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00037047:insoluble_protein
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00038289:oocyte_protein
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045521:Gender_Neutral
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00050234:lin-28(RNAi)_upregulated
      WBPaper00050743:elli-1(sam-3)_downregulated
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051245:body-wall-muscle_cytoplasm_expressed
      WBPaper00051245:body-wall-muscle_nucleus_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:intestine_nucleus_expressed
      WBPaper00051245:nucleus_specific
      WBPaper00052987:UV_upregulated_xpc-1;csb-1
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053302:alovudine_72h_regulated
      WBPaper00053321:embryo-to-L1_upregulated_WT_SMARTseq
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_downregulated_L1_SMARTseq
      WBPaper00053388:dauer_regulated_Cluster6
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00053810:isp-1(qm150)_downregulated
      WBPaper00053810:nuo-6(qm200)_downregulated
      WBPaper00054571:BPA_F3_germline_upregulated
      WBPaper00055354:Rapamycin-Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Psora_downregulated
      WBPaper00055354:Rifampicin-Psora_downregulated
      WBPaper00055648:germline_expressed
      WBPaper00055827:daf-2(e1370)_downregulated
      WBPaper00055827:pfd-6(gk493446)_downregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_downregulated_N2
      WBPaper00056165:MINA-1_interacting_mRNA
      WBPaper00056275:P.aeruginosa_upregulated
      WBPaper00056275:P.aeruginosa_upregulated_atf-7(qd22qd130)_dependent
      WBPaper00058691:CFP-1_interacting_protein
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059471:EGL-43_interacting
      WBPaper00059605:MUT-16_interacting
      WBPaper00059664:srbc-48(ac23)_downregulated
      WBPaper00059763:neuron_expressed
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00060014:set-2(tm1630)_upregulated
      WBPaper00060459:bcat-1(RNAi)_downregulated
      WBPaper00061527:tub-2_4713-daf-2_5288
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062498:PPM-1.D_interacting
      WBPaper00062554:MAGU-2_interacting
      WBPaper00064071:NHR-49_interacting
      WBPaper00064716:paraquat_upregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065158:AFD_enriched
      WBPaper00065975:P-body_vs_oocyte_enriched
      WBPaper00065975:P-body_vs_WholeAnimal_enriched
      WBPaper00065993:glp-1(e2141)_downregulated
      cgc4489_group_8
      WBPaper00025032:cluster_48
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00031003:24hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00032165:differentially_expressed_with_age_medoid_1
      WBPaper00035905:FBF-1_Associated
      WBPaper00036123:Atrazine_regulated
      WBPaper00038231:Cry5B_1.5-fold_downregulated
      WBPaper00040876:mir-35_downregulated
      WBPaper00041207:CE_dauer_down
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      [cgc5976]:class_2
    Interaction (208)
  Map_info: Map: IV Position: 16.1894 Error: 0.007025
    Positive: Positive_clone: Y116A8C Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (15)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene