WormBase Tree Display for Gene: WBGene00006729
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| WBGene00006729 | Evidence | Person_evidence | WBPerson696 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | K07B1 | ||||||
| Identity | Version | 2 | |||||||
| Name | CGC_name | ucp-4 | Person_evidence | WBPerson696 | |||||
| Sequence_name | K07B1.3 | ||||||||
| Molecular_name | K07B1.3 | ||||||||
| K07B1.3.1 | |||||||||
| CE28591 | |||||||||
| K07B1.3.2 | |||||||||
| Other_name | slc-25A27 | Person_evidence | WBPerson555 | ||||||
| CELE_K07B1.3 | Accession_evidence | NDB | BX284605 | ||||||
| Public_name | ucp-4 | ||||||||
| DB_info | Database | AceView | gene | 5J815 | |||||
| WormQTL | gene | WBGene00006729 | |||||||
| WormFlux | gene | WBGene00006729 | |||||||
| NDB | locus_tag | CELE_K07B1.3 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00006729|UniProtKB=O01883 | |||||||
| family | PTHR45618 | ||||||||
| NCBI | gene | 179315 | |||||||
| RefSeq | protein | NM_073013.8 | |||||||
| TREEFAM | TREEFAM_ID | TF354328 | |||||||
| TrEMBL | UniProtAcc | O01883 | |||||||
| UniProt_GCRP | UniProtAcc | O01883 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:41 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 27 Apr 2016 13:43:44 | WBPerson2970 | Name_change | Other_name | slc-25A27 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ucp | ||||||||
| Allele (35) | |||||||||
| Strain | WBStrain00031433 | ||||||||
| WBStrain00005332 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00026043 | ||||||||
| 00026044 | |||||||||
| 00026045 | |||||||||
| 00026046 | |||||||||
| 00026047 | |||||||||
| 00026048 | |||||||||
| 00026049 | |||||||||
| Contained_in_operon | CEOP5224 | ||||||||
| Ortholog (39) | |||||||||
| Paralog (35) | |||||||||
| Structured_description | Concise_description | ucp-4 encodes an uncoupling protein related to mammalian mitochondrial uncoupling protein 4 (UCP4) also known as solute carrier family 25, member 27 (SLC25A27); UCP-4 is predicted to function to uncouple ATP production from electron transport and, consistent with this, ucp-4 mutant animals contain elevated ATP levels; ucp-4 activity is also required for normal rates of survival in response to cold treatment; a ucp-4::gfp promoter fusion is expressed in head and body wall muscles and in the pharynx. | Paper_evidence | WBPaper00025191 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 26 Oct 2011 00:00:00 | ||||||||
| Automated_description | Predicted to enable transmembrane transporter activity. Involved in response to cold. Predicted to be located in membrane. Expressed in head muscle; head neurons; hypodermis; pharyngeal muscle cell; and pharynx. Human ortholog(s) of this gene implicated in schizophrenia. Is an ortholog of human SLC25A27 (solute carrier family 25 member 27). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:5419 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:21065) | ||||
| Molecular_info | Corresponding_CDS | K07B1.3 | |||||||
| Corresponding_transcript | K07B1.3.1 | ||||||||
| K07B1.3.2 | |||||||||
| Other_sequence (19) | |||||||||
| Associated_feature | WBsf232240 | ||||||||
| Experimental_info | RNAi_result (12) | ||||||||
| Expr_pattern | Expr3239 | ||||||||
| Expr13140 | |||||||||
| Expr1018423 | |||||||||
| Expr1032805 | |||||||||
| Expr1153813 | |||||||||
| Expr2017735 | |||||||||
| Expr2035874 | |||||||||
| Drives_construct | WBCnstr00011244 | ||||||||
| WBCnstr00015681 | |||||||||
| WBCnstr00015682 | |||||||||
| WBCnstr00015923 | |||||||||
| WBCnstr00015925 | |||||||||
| WBCnstr00015927 | |||||||||
| WBCnstr00015929 | |||||||||
| WBCnstr00034190 | |||||||||
| WBCnstr00038589 | |||||||||
| WBCnstr00038590 | |||||||||
| Construct_product | WBCnstr00034190 | ||||||||
| WBCnstr00038590 | |||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (89) | |||||||||
| Interaction (17) | |||||||||
| Map_info | Map | V | Position | 1.99099 | Error | 0.001988 | |||
| Positive | Positive_clone | K07B1 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4426 | |||||||
| 5091 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (18) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
