WormBase Tree Display for Gene: WBGene00006743
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| WBGene00006743 | SMap | S_parent | Sequence | CHROMOSOME_X | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | unc-3 | Person_evidence | WBPerson261 | |||||
| Sequence_name | Y16B4A.1 | ||||||||
| Molecular_name | Y16B4A.1 | ||||||||
| Y16B4A.1.1 | |||||||||
| CE29366 | |||||||||
| Other_name | CELE_Y16B4A.1 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | unc-3 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:41 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | unc | ||||||||
| Reference_allele | WBVar00142996 | ||||||||
| Allele (232) | |||||||||
| Legacy_information | e151 : weak coiler tends to coil tail active; very disorganized ventral nerve cord; mutant focus in ABp descendants; ES3 ME1. Similar phenotype in e151/Df. NA4 (e54 (weaker allele) e95 etc.). | ||||||||
| [C.elegansII] e151 : weak coiler tends to coil, tail active, good head movement; very disorganized ventral nerve cord; mosaic analysis indicates mutant focus in ventral cord motor neurons. Similar phenotype ine151/Df. ES3 ME1.OA>5: e54 (weaker allele), e95, mn419, p1001 etc. Cloned: polymorphisms identified in mn419 and derivatives (cosmid F42D1). [Brenner 1974; Herman and Kari 1987; NG; SP] | |||||||||
| Strain | WBStrain00023812 | ||||||||
| WBStrain00023947 | |||||||||
| WBStrain00026971 | |||||||||
| WBStrain00027004 | |||||||||
| WBStrain00027373 | |||||||||
| WBStrain00027376 | |||||||||
| WBStrain00029078 | |||||||||
| WBStrain00029632 | |||||||||
| WBStrain00029635 | |||||||||
| WBStrain00029636 | |||||||||
| WBStrain00029770 | |||||||||
| WBStrain00030773 | |||||||||
| WBStrain00030774 | |||||||||
| WBStrain00030800 | |||||||||
| WBStrain00030840 | |||||||||
| WBStrain00031247 | |||||||||
| WBStrain00033501 | |||||||||
| WBStrain00034123 | |||||||||
| WBStrain00034124 | |||||||||
| WBStrain00034129 | |||||||||
| WBStrain00034130 | |||||||||
| WBStrain00034131 | |||||||||
| WBStrain00034132 | |||||||||
| WBStrain00034133 | |||||||||
| WBStrain00034135 | |||||||||
| WBStrain00034136 | |||||||||
| WBStrain00034137 | |||||||||
| WBStrain00034138 | |||||||||
| WBStrain00034157 | |||||||||
| WBStrain00034158 | |||||||||
| WBStrain00034159 | |||||||||
| WBStrain00034160 | |||||||||
| WBStrain00034161 | |||||||||
| WBStrain00034162 | |||||||||
| WBStrain00034163 | |||||||||
| WBStrain00034164 | |||||||||
| WBStrain00034165 | |||||||||
| WBStrain00034166 | |||||||||
| WBStrain00034167 | |||||||||
| WBStrain00034168 | |||||||||
| WBStrain00034169 | |||||||||
| WBStrain00034170 | |||||||||
| WBStrain00034171 | |||||||||
| WBStrain00034172 | |||||||||
| WBStrain00034173 | |||||||||
| WBStrain00034174 | |||||||||
| WBStrain00034175 | |||||||||
| WBStrain00034176 | |||||||||
| WBStrain00034177 | |||||||||
| WBStrain00034178 | |||||||||
| WBStrain00034179 | |||||||||
| WBStrain00034180 | |||||||||
| WBStrain00034200 | |||||||||
| WBStrain00034217 | |||||||||
| WBStrain00034218 | |||||||||
| WBStrain00034222 | |||||||||
| WBStrain00034223 | |||||||||
| WBStrain00034225 | |||||||||
| WBStrain00034230 | |||||||||
| WBStrain00034255 | |||||||||
| WBStrain00034309 | |||||||||
| WBStrain00034327 | |||||||||
| WBStrain00034333 | |||||||||
| WBStrain00034390 | |||||||||
| WBStrain00034395 | |||||||||
| WBStrain00034396 | |||||||||
| WBStrain00034473 | |||||||||
| WBStrain00000060 | |||||||||
| WBStrain00000292 | |||||||||
| WBStrain00004111 | |||||||||
| WBStrain00004959 | |||||||||
| WBStrain00004966 | |||||||||
| WBStrain00004967 | |||||||||
| WBStrain00004968 | |||||||||
| WBStrain00004971 | |||||||||
| WBStrain00004972 | |||||||||
| WBStrain00004973 | |||||||||
| WBStrain00004977 | |||||||||
| WBStrain00004981 | |||||||||
| WBStrain00005008 | |||||||||
| WBStrain00005829 | |||||||||
| WBStrain00006190 | |||||||||
| WBStrain00006361 | |||||||||
| WBStrain00007936 | |||||||||
| WBStrain00008056 | |||||||||
| WBStrain00005019 | |||||||||
| WBStrain00005025 | |||||||||
| WBStrain00047343 | |||||||||
| WBStrain00047344 | |||||||||
| WBStrain00047339 | |||||||||
| WBStrain00047342 | |||||||||
| WBStrain00051010 | |||||||||
| WBStrain00051965 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (27) | |||||||||
| Ortholog (46) | |||||||||
| Structured_description | Automated_description | Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; histone acetyltransferase binding activity; and identical protein binding activity. Involved in several processes, including dauer larval development; neuron differentiation; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in ABalappaap; ABalappaapp; and neurons. Human ortholog(s) of this gene implicated in hypotonia, ataxia, and delayed development syndrome. Is an ortholog of several human genes including EBF1 (EBF transcription factor 1); EBF2 (EBF transcription factor 2); and EBF4 (EBF family member 4). | Paper_evidence | WBPaper00065943 | |||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0081176 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:19087) | ||||
| Molecular_info | Corresponding_CDS | Y16B4A.1 | |||||||
| Corresponding_CDS_history | Y16B4A.1:wp62 | ||||||||
| Corresponding_transcript | Y16B4A.1.1 | ||||||||
| Other_sequence (23) | |||||||||
| Associated_feature | WBsf648757 | ||||||||
| WBsf648758 | |||||||||
| WBsf663592 | |||||||||
| WBsf663593 | |||||||||
| WBsf663594 | |||||||||
| WBsf663595 | |||||||||
| WBsf663596 | |||||||||
| WBsf978939 | |||||||||
| WBsf1008002 | |||||||||
| WBsf1008003 | |||||||||
| WBsf1008004 | |||||||||
| WBsf1008005 | |||||||||
| WBsf1008006 | |||||||||
| WBsf1008007 | |||||||||
| WBsf1024459 | |||||||||
| WBsf1024460 | |||||||||
| WBsf1024461 | |||||||||
| WBsf1024462 | |||||||||
| WBsf236718 | |||||||||
| Transcription_factor | WBTranscriptionFactor000217 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00115872 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00090173 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00090014 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00027739 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00020068 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00055554 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00062789 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00008787 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00090332 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00089778 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern (13) | |||||||||
| Drives_construct (11) | |||||||||
| Construct_product (14) | |||||||||
| Antibody | WBAntibody00000177 | ||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (188) | |||||||||
| Interaction (195) | |||||||||
| Map_info | Map | X | Position | 21.3208 | Error | 0.014822 | |||
| Well_ordered | |||||||||
| Positive | Positive_clone | F42D1 | |||||||
| Y16B4A | Inferred_automatically | From sequence, transcript, pseudogene data | |||||||
| Negative | Negative_clone | K01B4 | |||||||
| Mapping_data | 2_point (52) | ||||||||
| Multi_point (53) | |||||||||
| Pos_neg_data (39) | |||||||||
| Landmark_gene | |||||||||
| Reference (217) | |||||||||
| Remark | [Eddy SR] EcoRV RFLP correlated with unc-3. 3.8 kb EcoRV band in N2, 2.3 kb in unc-3 (mn419), 3.8 kb again in revertants unc-3 (mn419 mn422) and unc-3 (mn419 mn426), 3.7 kb in revertant unc-3 (mn419 mn431). | ||||||||
| Polymorphism detection method = Southern hybridisation krb 04/03/02 | |||||||||
| Method | Gene |
