WormBase Tree Display for Gene: WBGene00006764
expand all nodes | collapse all nodes | view schema
| WBGene00006764 | Evidence | CGC_data_submission | |||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | ZK721 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | unc-27 | Person_evidence | WBPerson261 | |||||
| Sequence_name | ZK721.2 | ||||||||
| Molecular_name | ZK721.2 | ||||||||
| ZK721.2.1 | |||||||||
| CE40008 | |||||||||
| Other_name | unc-99 | ||||||||
| tni-2 | |||||||||
| CELE_ZK721.2 | Accession_evidence | NDB | BX284606 | ||||||
| Public_name | unc-27 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:42 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | unc | ||||||||
| Reference_allele | WBVar00142999 | ||||||||
| Allele (25) | |||||||||
| Legacy_information | e155 : sluggish poor backing slightly dumpy; abnormal body muscle; ES3 ME2. NA1. | ||||||||
| [C.elegansII] e155 : sluggish, poor backing, slightly dumpy; abnormal body muscle; some neuroanatomical defects. ES3 ME2. NA1. Also sd alleles:su142sd (pka unc-99, very slow, almost paralysed; can lay eggs; abnormal faint muscle birefringence and ultrastructure, collections of thick or thin filaments. ES3 ME1). OA3 (sd):su195 (forms thin filament paracrystals), su215 etc. [Brenner 1974; Zengel and Epstein 1980;SQ] | |||||||||
| [C.elegansII] NMK. Encodes predicted protein with similarity to troponin I.tni-2:lacZ expressed in body wall muscle. | |||||||||
| Strain | WBStrain00004113 | ||||||||
| WBStrain00006356 | |||||||||
| WBStrain00008392 | |||||||||
| WBStrain00008395 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00092604 | ||||||||
| 00092605 | |||||||||
| 00092606 | |||||||||
| 00092607 | |||||||||
| 00092608 | |||||||||
| 00092609 | |||||||||
| 00092610 | |||||||||
| 00092611 | |||||||||
| 00114771 | |||||||||
| Ortholog (58) | |||||||||
| Paralog | WBGene00006584 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00006585 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00006586 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | unc-27 encodes a troponin I isoform; unc-27 is required for coordinated motility and normal muscle morphology; structural analyses indicate that unc-27 is required for proper sarcomeric organization; unc-27/troponin I interacts with the body wall and pharynx types of troponin C; expression studies show that unc-27 is expressed in body wall, vulval and anal muscles. | Paper_evidence | WBPaper00006358 | |||||
| WBPaper00025009 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 29 Jan 2007 00:00:00 | ||||||||
| Automated_description | Enables troponin C binding activity. Involved in locomotion and sarcomere organization. Located in sarcomere. Expressed in body wall musculature; non-striated muscle; and rectal muscle. Human ortholog(s) of this gene implicated in several diseases, including arthrogryposis multiplex congenita; distal arthrogryposis type 2B1; and intrinsic cardiomyopathy (multiple). Is an ortholog of human TNNI1 (troponin I1, slow skeletal type); TNNI2 (troponin I2, fast skeletal type); and TNNI3 (troponin I3, cardiac type). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:397 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11947) | ||||
| DOID:0110313 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11947) | ||||||
| DOID:0111600 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11946) | ||||||
| DOID:11984 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11947) | ||||||
| DOID:0111425 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11947) | ||||||
| DOID:0110459 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11947) | ||||||
| DOID:0080954 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11946) | ||||||
| DOID:0110460 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11947) | ||||||
| DOID:12930 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11947) | ||||||
| DOID:3393 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11947) | ||||||
| Molecular_info | Corresponding_CDS | ZK721.2 | |||||||
| Corresponding_CDS_history | ZK721.2:wp155 | ||||||||
| Corresponding_transcript | ZK721.2.1 | ||||||||
| Other_sequence (139) | |||||||||
| Associated_feature | WBsf047563 | ||||||||
| WBsf663058 | |||||||||
| WBsf1006242 | |||||||||
| WBsf1006243 | |||||||||
| WBsf1006244 | |||||||||
| WBsf1006245 | |||||||||
| WBsf1023461 | |||||||||
| WBsf1023462 | |||||||||
| WBsf1023463 | |||||||||
| WBsf1023464 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00059692 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00022149 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00078122 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00078124 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00089780 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00066653 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00089997 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00090315 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00090156 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr2837 | ||||||||
| Expr4559 | |||||||||
| Expr4736 | |||||||||
| Expr4739 | |||||||||
| Expr4740 | |||||||||
| Expr4741 | |||||||||
| Expr4742 | |||||||||
| Expr10614 | |||||||||
| Expr12660 | |||||||||
| Expr1022908 | |||||||||
| Expr1032837 | |||||||||
| Expr1163107 | |||||||||
| Expr2017860 | |||||||||
| Expr2035996 | |||||||||
| Drives_construct | WBCnstr00000172 | ||||||||
| WBCnstr00012211 | |||||||||
| WBCnstr00012215 | |||||||||
| WBCnstr00034165 | |||||||||
| Construct_product | WBCnstr00000172 | ||||||||
| WBCnstr00034165 | |||||||||
| Antibody | WBAntibody00001011 | ||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (223) | |||||||||
| Interaction (105) | |||||||||
| Map_info | Map | X | Position | 0.395061 | Error | 0.010063 | |||
| Well_ordered | |||||||||
| Positive | Positive_clone | ZK721 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | 2_point (12) | ||||||||
| Multi_point (25) | |||||||||
| Pos_neg_data (12) | |||||||||
| Reference (38) | |||||||||
| Remark | Sequence connection from [Priest J, Allen T] | ||||||||
| old_name tni-2 becomes new_name unc-27 from [Priest J, Allen T]. | |||||||||
| Method | Gene |
