WormBase Tree Display for Gene: WBGene00006780
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| WBGene00006780 | SMap | S_parent | Sequence | B0350 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name (5) | |||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:42 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 10 Jun 2014 12:12:12 | WBPerson1983 | Event | Acquires_merge | WBGene00043083 | ||||
| Acquires_merge | WBGene00043083 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | unc | ||||||||
| Reference_allele | WBVar00143148 | ||||||||
| Allele (348) | |||||||||
| Possibly_affected_by | WBVar02153168 | ||||||||
| WBVar02156988 | |||||||||
| Legacy_information | e362 : paralysed coiler dumpy tends to curl; weak FITC uptake; amphid phasmid and PDE axons abnormal. ES3 ME0. NA11 (e427 e638 etc.). | ||||||||
| See also e638, e688, e715, e781, e783, e975, e1133, e1197, e1211, e1260 | |||||||||
| [C.elegansII] e362 : paralysed coiler, dumpy, tends to curl; weak FITC uptake; amphid, phasmid,PVP, PDE and other axons abnormal. ES3 ME0. NA11: e427, e638, e1197 (multiple defects in axonal elongation, fasciculation etc.), e1260,q331:Tc1, rh1013::Tc1, st200::Tc5, etc. Cloned: multiple transcripts up to 14 kb in length, encoding proteins related to mammalian ankyrin, up to 23 repeats of 33 aa ANK repeat [McIntire et al. 1992; Otsuka et al. 1995; DD] | |||||||||
| Strain (13) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (20) | |||||||||
| Ortholog (57) | |||||||||
| Paralog | WBGene00002069 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WBGene00009064 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| WBGene00012124 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00011240 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00007252 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00021304 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Automated_description | Enables cell adhesion molecule binding activity. Involved in several processes, including axon guidance; establishment or maintenance of cytoskeleton polarity; and regulation of cellular component organization. Located in lateral plasma membrane. Expressed in hermaphrodite gonad; hypodermis; intestinal cell; and vulval cell. Human ortholog(s) of this gene implicated in several diseases, including ankyrin-B-related cardiac arrhythmia; autosomal recessive intellectual developmental disorder 37; and heart conduction disease (multiple). Is an ortholog of human ANK2 (ankyrin 2) and ANK3 (ankyrin 3). | Paper_evidence | WBPaper00065943 | |||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:3312 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:494) | ||||
| DOID:0111700 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:493) | ||||||
| DOID:12971 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:492) | ||||||
| DOID:2843 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:493) | ||||||
| DOID:13884 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:493) | ||||||
| DOID:0081202 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:494) | ||||||
| DOID:2355 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:492) | ||||||
| DOID:0110916 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:492) | ||||||
| DOID:0060224 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:493) | ||||||
| DOID:5419 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:494) | ||||||
| Molecular_info | Corresponding_CDS | B0350.2a | |||||||
| B0350.2b | |||||||||
| B0350.2c | |||||||||
| B0350.2d | |||||||||
| B0350.2e | |||||||||
| B0350.2f | |||||||||
| B0350.2h | |||||||||
| B0350.2i | |||||||||
| B0350.2j | |||||||||
| Corresponding_CDS_history | B0350.2a:wp246 | ||||||||
| B0350.2b:wp134 | |||||||||
| B0350.2d:wp134 | |||||||||
| B0350.2g:wp262 | |||||||||
| Corresponding_transcript | B0350.2a.1 | ||||||||
| B0350.2b.1 | |||||||||
| B0350.2c.1 | |||||||||
| B0350.2d.1 | |||||||||
| B0350.2e.1 | |||||||||
| B0350.2f.1 | |||||||||
| B0350.2h.1 | |||||||||
| B0350.2i.1 | |||||||||
| B0350.2j.1 | |||||||||
| Other_sequence (158) | |||||||||
| Associated_feature (63) | |||||||||
| Experimental_info | RNAi_result (17) | ||||||||
| Expr_pattern (11) | |||||||||
| Drives_construct | WBCnstr00003400 | ||||||||
| Antibody | WBAntibody00000280 | ||||||||
| WBAntibody00000461 | |||||||||
| Microarray_results (82) | |||||||||
| Expression_cluster (272) | |||||||||
| Interaction (55) | |||||||||
| Map_info | Map | IV | Position | 2.88585 | |||||
| Well_ordered | |||||||||
| Positive | Inside_rearr | nDp5 | |||||||
| Positive_clone | B0350 | Inferred_automatically | From sequence, transcript, pseudogene data | ||||||
| DD#LRF1 | |||||||||
| Mapping_data | 2_point | 110 | |||||||
| 825 | |||||||||
| Multi_point (34) | |||||||||
| Pos_neg_data | 9034 | ||||||||
| Reference (149) | |||||||||
| Remark | [140610 pad] Gene was missing Acquires_merge Event history data so inferred from Acquires_merge tag. | ||||||||
| Method | Gene |
