WormBase Tree Display for Gene: WBGene00006790
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| WBGene00006790 | SMap | S_parent | Sequence | F55D12 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | unc-55 | Person_evidence | WBPerson261 | |||||
| Sequence_name | F55D12.4 | ||||||||
| Molecular_name | F55D12.4a | ||||||||
| F55D12.4a.1 | |||||||||
| CE43454 | |||||||||
| F55D12.4b | |||||||||
| CE43459 | |||||||||
| F55D12.4b.1 | |||||||||
| Other_name | CELE_F55D12.4 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | unc-55 | ||||||||
| DB_info | Database | WormQTL | gene | WBGene00006790 | |||||
| WormFlux | gene | WBGene00006790 | |||||||
| NDB | locus_tag | CELE_F55D12.4 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00006790|UniProtKB=G5ECR9 | |||||||
| family | PTHR24082 | ||||||||
| NCBI | gene | 192082 | |||||||
| RefSeq | protein | NM_001129010.3 | |||||||
| NM_001129011.4 | |||||||||
| SwissProt | UniProtAcc | G5ECR9 | |||||||
| TREEFAM | TREEFAM_ID | TF315716 | |||||||
| UniProt_GCRP | UniProtAcc | G5ECR9 | |||||||
| OMIM | gene | 107773 | |||||||
| 132890 | |||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:43 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | unc | ||||||||
| Reference_allele | WBVar00143181 | ||||||||
| Allele (76) | |||||||||
| Legacy_information | e402 : slow very poor backing tends to coil healthy; abnormal VD neurons. ES3 ME0. NA2 (e523). | ||||||||
| [C.elegansII] e402 : slow, very poor backing, tends to coil ventrally; healthy; abnormal VD neurons (adopt DD synaptic pattern). Mosaic analysis indicates focus in VD neurons.ES3 ME0. OA>11: e523 etc. [Walthall and Plunkett 1995; ER] | |||||||||
| Strain | WBStrain00034109 | ||||||||
| WBStrain00036833 | |||||||||
| WBStrain00037233 | |||||||||
| WBStrain00040603 | |||||||||
| WBStrain00004259 | |||||||||
| WBStrain00004160 | |||||||||
| WBStrain00006182 | |||||||||
| WBStrain00007564 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (17) | |||||||||
| Ortholog (42) | |||||||||
| Paralog (223) | |||||||||
| Structured_description | Concise_description | unc-55 encodes a nuclear receptor that is most closely related to Drosophila Seven-up and the vertebrate COUP (chicken ovalbumin upstream promoter) transcription factors; unc-55 activity is required for the VD motor neurons to adopt their normal synaptic pattern; unc-55 is expressed in a number of neurons, including the VD motor neurons. | Paper_evidence | WBPaper00003317 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 May 2007 00:00:00 | ||||||||
| Automated_description | Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Involved in cell fate specification and negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in motor neurons; somatic nervous system; and spicule muscle. Human ortholog(s) of this gene implicated in 46,XX sex reversal 5 and Bosch-Boonstra-Schaaf optic atrophy syndrome. Is an ortholog of human NR2F1 (nuclear receptor subfamily 2 group F member 1) and NR2F2 (nuclear receptor subfamily 2 group F member 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model (2) | ||||||||
| Molecular_info | Corresponding_CDS | F55D12.4a | |||||||
| F55D12.4b | |||||||||
| Corresponding_CDS_history | F55D12.4:wp183 | ||||||||
| F55D12.4a:wp199 | |||||||||
| F55D12.4b:wp199 | |||||||||
| Corresponding_transcript | F55D12.4a.1 | ||||||||
| F55D12.4b.1 | |||||||||
| Other_sequence | CBC06960_1 | ||||||||
| CD203056.1 | |||||||||
| LSC01304_1 | |||||||||
| CJC05575_1 | |||||||||
| Associated_feature | WBsf984306 | ||||||||
| WBsf984307 | |||||||||
| WBsf984308 | |||||||||
| WBsf984309 | |||||||||
| WBsf984310 | |||||||||
| WBsf1010164 | |||||||||
| WBsf1010165 | |||||||||
| WBsf1010166 | |||||||||
| Gene_product_binds (375) | |||||||||
| Transcription_factor | WBTranscriptionFactor000220 | ||||||||
| Experimental_info | RNAi_result (16) | ||||||||
| Expr_pattern | Expr1289 | ||||||||
| Expr8357 | |||||||||
| Expr10750 | |||||||||
| Expr14544 | |||||||||
| Expr15096 | |||||||||
| Expr1015404 | |||||||||
| Expr1152291 | |||||||||
| Expr2017888 | |||||||||
| Expr2036024 | |||||||||
| Drives_construct | WBCnstr00000675 | ||||||||
| WBCnstr00000676 | |||||||||
| WBCnstr00005423 | |||||||||
| WBCnstr00005424 | |||||||||
| WBCnstr00005425 | |||||||||
| WBCnstr00009985 | |||||||||
| WBCnstr00010194 | |||||||||
| WBCnstr00014484 | |||||||||
| WBCnstr00015840 | |||||||||
| WBCnstr00034148 | |||||||||
| Construct_product | WBCnstr00005423 | ||||||||
| WBCnstr00005424 | |||||||||
| WBCnstr00005425 | |||||||||
| WBCnstr00034148 | |||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (82) | |||||||||
| Interaction (103) | |||||||||
| Product_binds_matrix | WBPmat00005573 | ||||||||
| Map_info | Map | I | Position | 2.38878 | Error | 0.002346 | |||
| Well_ordered | |||||||||
| Positive | Positive_clone | F55D12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | 2_point | 17 | |||||||
| 7148 | |||||||||
| Multi_point (11) | |||||||||
| Pos_neg_data | 5103 | ||||||||
| 5104 | |||||||||
| 5105 | |||||||||
| 5848 | |||||||||
| 5955 | |||||||||
| 3745 | |||||||||
| Reference (70) | |||||||||
| Method | Gene |
