WormBase Tree Display for Gene: WBGene00006794

WBGene00006794 SMap: S_parent: Sequence: CHROMOSOME_V
  Identity: Version: 2
    Name: CGC_name: unc-60 Person_evidence: WBPerson77
      Sequence_name: C38C3.5
      Molecular_name: C38C3.5
        C38C3.5.1
        CE20549
      Other_name: unc-66
        C38C3.f Curator_confirmed: WBPerson1983
          Remark: Old cosmid naming mapped via unique overlapping PCR_product on CDSs
        CELE_C38C3.5 Accession_evidence: NDB BX284605
      Public_name: unc-60
    DB_info: Database: AceView gene 5B957
        WormQTL gene WBGene00006794
        WormFlux gene WBGene00006794
        NDB locus_tag CELE_C38C3.5
        Panther gene CAEEL|WormBase=WBGene00006794|UniProtKB=Q07750
          family PTHR11913
        NCBI gene 178640
        RefSeq protein NM_071026.11
        SwissProt UniProtAcc Q07749
        OMIM gene 601443
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:43 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 06 Mar 2018 14:39:08 WBPerson4025 Event: Split_into: WBGene00302980
      Split_into: WBGene00302980
    Status: Live
  Gene_info (13)
  Disease_info: Potential_model: DOID:4948 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1874)
      DOID:0110934 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1875)
      DOID:11457 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1874)
  Molecular_info: Corresponding_CDS: C38C3.5
    Corresponding_CDS_history: C38C3.5a:wp264
      C38C3.5b:wp86
      C38C3.5b:wp249
      C38C3.5c:wp264
    Corresponding_transcript: C38C3.5.1
    Other_sequence (212)
    Associated_feature (19)
  Experimental_info: RNAi_result (17)
    Expr_pattern (11)
    Drives_construct: WBCnstr00019150
      WBCnstr00034145
    Construct_product: WBCnstr00015454
      WBCnstr00015473
      WBCnstr00015475
      WBCnstr00015476
      WBCnstr00015477
      WBCnstr00015478
      WBCnstr00019150
      WBCnstr00019151
      WBCnstr00019152
      WBCnstr00034145
    Antibody: WBAntibody00000222
      WBAntibody00000223
      WBAntibody00002955
    Microarray_results (24)
    Expression_cluster: WBPaper00028360:Phospho-Sulfo-Modified_proteins
      WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00032031:DConiospora_downregulated_OligoArray_24h
      WBPaper00032425:up_in_alg-1
      WBPaper00032425:up_in_lin-35
      WBPaper00032425:up_in_zfp-1
      WBPaper00032528:L3_enriched
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00035926:A.hydrophila_regulated
      WBPaper00037047:aging_accelerated_insoluble_protein
      WBPaper00037047:insoluble_protein
      WBPaper00038118:aak-2(gt33)_upregulated
      WBPaper00038118:stress_upregulated_N2
      WBPaper00038237:age-1_upregulated_intestine_rescue
      WBPaper00038237:age-1_upregulated_neuron_rescue
      WBPaper00038237:age-1_upregulated_nontransgenic
      WBPaper00038289:oocyte_protein
      WBPaper00038357:atx-3_regulated_heat-shock
      WBPaper00038438:Harposporium_24hr_downregulated_RNAseq
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00040755:LRRK2(wt)-Tau_vs_N2_downregulated
      WBPaper00040755:LRRK2(wt)-Tau_vs_Tau_upregulated
      WBPaper00041072:UTX-1_interacting_protein
      WBPaper00041257:irradiation_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044746:aging_upregulated_Day5
      WBPaper00044746:aging_upregulated_HeatShock
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_downregulated
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045417:128Q-huntingtin_downreglated
      WBPaper00045417:128Q-huntingtin_upreglated
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_upregulated
      WBPaper00045861:wdr-5(ok1417)_downregulated
      WBPaper00046691:P1_enriched
      WBPaper00048810:CoQ-deficiency_downregulated
      WBPaper00048910:mRNA-interacting_protein
      WBPaper00048988:neuron_expressed
      WBPaper00049626:UNC-75_target
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050599:nicotine(0.01mM)_upregulated
      WBPaper00050599:nicotine(1mM)_upregulated
      WBPaper00050698:DEP-1_interacting
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:intestine_nucleus_expressed
      WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_24h_regulated
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_L1_SMARTseq
      WBPaper00053388:dauer_regulated_Cluster6
      WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_upregulated
      WBPaper00053615:SMO-1_target
      WBPaper00053810:isp-1(qm150)_downregulated
      WBPaper00053814:25C_downregulated_OP50
      WBPaper00054192:cold-shock_upregulated
      WBPaper00055049:S.gordonii_upregulated
      WBPaper00055648:germline_expressed
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056139:soil-microbiota_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00057041:spc-1(cas971)_upregulated
      WBPaper00057041:unc-70(cas983)_upregulated
      WBPaper00057136:yap-1(ys38)_upregulated
      WBPaper00057288:Cold_upregulated_transcript
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058691:CFP-1_interacting_protein
      WBPaper00059174:MEG-3_interacting
      WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059440:LAG-1_activated_4hr-auxin
      WBPaper00059471:EGL-43_interacting
      WBPaper00059605:MUT-16_interacting
      WBPaper00059763:neuron_expressed
      WBPaper00059987:Wounding_upregulated
      WBPaper00060084:cco-1(RNAi)_downregulated_N2
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:mu_sph
      WBPaper00061377:MYRF-1_interacting
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
      WBPaper00061478:SUMO-conjugated_protein
      WBPaper00061527:cids-2_2203-attf-2_2451
      WBPaper00061527:dld-1-skn-1_16701
      WBPaper00061527:gpb-1_3783-C48A7.2_22459
      WBPaper00061527:mup-2-unc-87_284
      WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062325:etr-1(lq61)_upregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062554:MAGU-2_interacting
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064055:trl-1(cas1077)_downregulated_starved
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064130:Beta-Amyloid_24h_upregulated_mRNA
      WBPaper00064315:mes-3(bn199)_downregulated_PGCs
      WBPaper00064505:tamoxifen_downregulated
      WBPaper00064933:E.coli-binding_secret_protein
      WBPaper00064992:Capsaicin_downregulated
      WBPaper00064992:Eugenol_downregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065835:Day5_vs_Day1_downregulated
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065841:1_1
      WBPaper00065841:7_2
      WBPaper00065841:7_3
      WBPaper00065841:7_4
      WBPaper00065841:38_3
      WBPaper00065841:143_0
      WBPaper00066093:E.coli-purE_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      cgc4386_cluster_3_5
      cgc4386_cluster_5_4
      WBPaper00024671:AFD_AWB_vs_unsorted_downregulated
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00030985:Enterococcus_faecalis_downregulated
      WBPaper00031003:0hr_muscle_enriched
      WBPaper00031003:24hr_muscle_enriched
      WBPaper00031003:hlh_1_enriched
      WBPaper00031003:total_muscle_enriched
      WBPaper00032948:FedUp
      WBPaper00033099:organophosphorus_pesticide_regulated
      WBPaper00035588:alg-1(-)_upregulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040823:alg-1(gk214)_upregulated
      WBPaper00040985:AIN-2_asynchronous_muscle
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(101_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_ME
      [cgc5767]:expression_class_SM
    Interaction (203)
    Anatomy_function: WBbtf0607
  Map_info: Map: V Position: -18.8768 Error: 0.017792
    Well_ordered
    Positive: Inside_rearr: sDf28
        rT1
      Positive_clone: C32E5
        C38C3 Inferred_automatically: From sequence, transcript, pseudogene data
        F53E2
    Mapping_data: 2_point (13)
      Multi_point (29)
      Pos_neg_data: 1793
        1799
        1805
        2166
        3092
        3257
        3096
        3105
        3582
        5182
    Landmark_gene
  Reference: WBPaper00000031
    WBPaper00000461
    WBPaper00000488
    WBPaper00000536
    WBPaper00000554
    WBPaper00000608
    WBPaper00000750
    WBPaper00000785
    WBPaper00000859
    WBPaper00001018
    WBPaper00001230
    WBPaper00001474
    WBPaper00001563
    WBPaper00001747
    WBPaper00001912
    WBPaper00002305
    WBPaper00003001
    WBPaper00003258
    WBPaper00003529
    WBPaper00003553
    WBPaper00003614
    WBPaper00004157
    WBPaper00004569
    WBPaper00004608
    WBPaper00004695
    WBPaper00004883
    WBPaper00005168
    WBPaper00005719
    WBPaper00005797
    WBPaper00005824
    WBPaper00005967
    WBPaper00006025
    WBPaper00006047
    WBPaper00006108
    WBPaper00006201
    WBPaper00011015
    WBPaper00011964
    WBPaper00013408
    WBPaper00013649
    WBPaper00013779
    WBPaper00013833
    WBPaper00014055
    WBPaper00014131
    WBPaper00014382
    WBPaper00014406
    WBPaper00014410
    WBPaper00014568
    WBPaper00014635
    WBPaper00014773
    WBPaper00015482
    WBPaper00015606
    WBPaper00015684
    WBPaper00015926
    WBPaper00015930
    WBPaper00016045
    WBPaper00016139
    WBPaper00016148
    WBPaper00016200
    WBPaper00016341
    WBPaper00016390
    WBPaper00016495
    WBPaper00016496
    WBPaper00016540
    WBPaper00016546
    WBPaper00017361
    WBPaper00017482
    WBPaper00019545
    WBPaper00019663
    WBPaper00021016
    WBPaper00022383
    WBPaper00022619
    WBPaper00023507
    WBPaper00024200
    WBPaper00024267
    WBPaper00024604
    WBPaper00025227
    WBPaper00025301
    WBPaper00026920
    WBPaper00027147
    WBPaper00027235
    WBPaper00027258
    WBPaper00028217
    WBPaper00028360
    WBPaper00028442
    WBPaper00028462
    WBPaper00029020
    WBPaper00030902
    WBPaper00031700
    WBPaper00032009
    WBPaper00032057
    WBPaper00032338
    WBPaper00032446
    WBPaper00032784
    WBPaper00032907
    WBPaper00033099
    WBPaper00035502
    WBPaper00036509
    WBPaper00037607
    WBPaper00038491
    WBPaper00040301
    WBPaper00041203
    WBPaper00041641
    WBPaper00042407
    WBPaper00043908
    WBPaper00043929
    WBPaper00045207
    WBPaper00045436
    WBPaper00045753
    WBPaper00046615
    WBPaper00049828
    WBPaper00052243
    WBPaper00054189
    WBPaper00055090
    WBPaper00056737
    WBPaper00058104
    WBPaper00058154
    WBPaper00059953
    WBPaper00064670
    WBPaper00064926
  Remark: [ Wakarchuck MF] dpy-18(e364)/eT1; unc-60(m35)/eT1 male was crossed to eT1(III;V); sEx9 [pRF4{rol-6(su1006)}+C32E5] hermaphrodite. F1 rollers segregated fertile Dpy non-Uncs among their progeny, indicating rescue of unc-60(m35).
  Method: Gene