WormBase Tree Display for Gene: WBGene00006794

WBGene00006794 SMap: S_parent: Sequence: CHROMOSOME_V
  Identity: Version: 2
    Name: CGC_name: unc-60 Person_evidence: WBPerson77
      Sequence_name: C38C3.5
      Molecular_name: C38C3.5
        C38C3.5.1
        CE20549
      Other_name: unc-66
        C38C3.f Curator_confirmed: WBPerson1983
          Remark: Old cosmid naming mapped via unique overlapping PCR_product on CDSs
        CELE_C38C3.5 Accession_evidence: NDB BX284605
      Public_name: unc-60
    DB_info: Database: AceView gene 5B957
        WormQTL gene WBGene00006794
        WormFlux gene WBGene00006794
        NDB locus_tag CELE_C38C3.5
        Panther gene CAEEL|WormBase=WBGene00006794|UniProtKB=Q07750
          family PTHR11913
        NCBI gene 178640
        RefSeq protein NM_071026.11
        SwissProt UniProtAcc Q07749
        OMIM gene 601443
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:43 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 06 Mar 2018 14:39:08 WBPerson4025 Event: Split_into: WBGene00302980
      Split_into: WBGene00302980
    Status: Live
  Gene_info (13)
  Disease_info: Potential_model: DOID:4948 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1874)
      DOID:0110934 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1875)
      DOID:11457 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1874)
  Molecular_info: Corresponding_CDS: C38C3.5
    Corresponding_CDS_history: C38C3.5a:wp264
      C38C3.5b:wp86
      C38C3.5b:wp249
      C38C3.5c:wp264
    Corresponding_transcript: C38C3.5.1
    Other_sequence (212)
    Associated_feature (19)
  Experimental_info: RNAi_result (17)
    Expr_pattern (11)
    Drives_construct: WBCnstr00019150
      WBCnstr00034145
    Construct_product: WBCnstr00015454
      WBCnstr00015473
      WBCnstr00015475
      WBCnstr00015476
      WBCnstr00015477
      WBCnstr00015478
      WBCnstr00019150
      WBCnstr00019151
      WBCnstr00019152
      WBCnstr00034145
    Antibody: WBAntibody00000222
      WBAntibody00000223
      WBAntibody00002955
    Microarray_results (24)
    Expression_cluster: WBPaper00028360:Phospho-Sulfo-Modified_proteins
      WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00032031:DConiospora_downregulated_OligoArray_24h
      WBPaper00032425:up_in_alg-1
      WBPaper00032425:up_in_lin-35
      WBPaper00032425:up_in_zfp-1
      WBPaper00032528:L3_enriched
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00035926:A.hydrophila_regulated
      WBPaper00037047:aging_accelerated_insoluble_protein
      WBPaper00037047:insoluble_protein
      WBPaper00038118:aak-2(gt33)_upregulated
      WBPaper00038118:stress_upregulated_N2
      WBPaper00038237:age-1_upregulated_intestine_rescue
      WBPaper00038237:age-1_upregulated_neuron_rescue
      WBPaper00038237:age-1_upregulated_nontransgenic
      WBPaper00038289:oocyte_protein
      WBPaper00038357:atx-3_regulated_heat-shock
      WBPaper00038438:Harposporium_24hr_downregulated_RNAseq
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00040755:LRRK2(wt)-Tau_vs_N2_downregulated
      WBPaper00040755:LRRK2(wt)-Tau_vs_Tau_upregulated
      WBPaper00041072:UTX-1_interacting_protein
      WBPaper00041257:irradiation_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044746:aging_upregulated_Day5
      WBPaper00044746:aging_upregulated_HeatShock
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_downregulated
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045417:128Q-huntingtin_downreglated
      WBPaper00045417:128Q-huntingtin_upreglated
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_upregulated
      WBPaper00045861:wdr-5(ok1417)_downregulated
      WBPaper00046691:P1_enriched
      WBPaper00048810:CoQ-deficiency_downregulated
      WBPaper00048910:mRNA-interacting_protein
      WBPaper00048988:neuron_expressed
      WBPaper00049626:UNC-75_target
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050599:nicotine(0.01mM)_upregulated
      WBPaper00050599:nicotine(1mM)_upregulated
      WBPaper00050698:DEP-1_interacting
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:intestine_nucleus_expressed
      WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_24h_regulated
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_L1_SMARTseq
      WBPaper00053388:dauer_regulated_Cluster6
      WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_upregulated
      WBPaper00053615:SMO-1_target
      WBPaper00053810:isp-1(qm150)_downregulated
      WBPaper00053814:25C_downregulated_OP50
      WBPaper00054192:cold-shock_upregulated
      WBPaper00055049:S.gordonii_upregulated
      WBPaper00055648:germline_expressed
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056139:soil-microbiota_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00057041:spc-1(cas971)_upregulated
      WBPaper00057041:unc-70(cas983)_upregulated
      WBPaper00057136:yap-1(ys38)_upregulated
      WBPaper00057288:Cold_upregulated_transcript
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058691:CFP-1_interacting_protein
      WBPaper00059174:MEG-3_interacting
      WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059440:LAG-1_activated_4hr-auxin
      WBPaper00059471:EGL-43_interacting
      WBPaper00059605:MUT-16_interacting
      WBPaper00059763:neuron_expressed
      WBPaper00059987:Wounding_upregulated
      WBPaper00060084:cco-1(RNAi)_downregulated_N2
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:mu_sph
      WBPaper00061377:MYRF-1_interacting
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
      WBPaper00061478:SUMO-conjugated_protein
      WBPaper00061527:cids-2_2203-attf-2_2451
      WBPaper00061527:dld-1-skn-1_16701
      WBPaper00061527:gpb-1_3783-C48A7.2_22459
      WBPaper00061527:mup-2-unc-87_284
      WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062325:etr-1(lq61)_upregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062554:MAGU-2_interacting
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064055:trl-1(cas1077)_downregulated_starved
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064130:Beta-Amyloid_24h_upregulated_mRNA
      WBPaper00064315:mes-3(bn199)_downregulated_PGCs
      WBPaper00064505:tamoxifen_downregulated
      WBPaper00064933:E.coli-binding_secret_protein
      WBPaper00064992:Capsaicin_downregulated
      WBPaper00064992:Eugenol_downregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065835:Day5_vs_Day1_downregulated
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065841:1_1
      WBPaper00065841:7_2
      WBPaper00065841:7_3
      WBPaper00065841:7_4
      WBPaper00065841:38_3
      WBPaper00065841:143_0
      WBPaper00066093:E.coli-purE_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      cgc4386_cluster_3_5
      cgc4386_cluster_5_4
      WBPaper00024671:AFD_AWB_vs_unsorted_downregulated
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00030985:Enterococcus_faecalis_downregulated
      WBPaper00031003:0hr_muscle_enriched
      WBPaper00031003:24hr_muscle_enriched
      WBPaper00031003:hlh_1_enriched
      WBPaper00031003:total_muscle_enriched
      WBPaper00032948:FedUp
      WBPaper00033099:organophosphorus_pesticide_regulated
      WBPaper00035588:alg-1(-)_upregulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040823:alg-1(gk214)_upregulated
      WBPaper00040985:AIN-2_asynchronous_muscle
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(101_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_ME
      [cgc5767]:expression_class_SM
    Interaction (203)
    Anatomy_function: WBbtf0607
  Map_info: Map: V Position: -18.8768 Error: 0.017792
    Well_ordered
    Positive (2)
    Mapping_data: 2_point (13)
      Multi_point (29)
      Pos_neg_data: 1793
        1799
        1805
        2166
        3092
        3257
        3096
        3105
        3582
        5182
    Landmark_gene
  Reference (119)
  Remark: [ Wakarchuck MF] dpy-18(e364)/eT1; unc-60(m35)/eT1 male was crossed to eT1(III;V); sEx9 [pRF4{rol-6(su1006)}+C32E5] hermaphrodite. F1 rollers segregated fertile Dpy non-Uncs among their progeny, indicating rescue of unc-60(m35).
  Method: Gene