| WBGene00006797 | SMap | S_parent | Sequence | Y110A7A |
|---|
| Identity | Version | 1 |
| | Name | CGC_name | unc-63 | Person_evidence | WBPerson261 |
| | | Sequence_name | Y110A7A.3 |
| | | Molecular_name | Y110A7A.3 |
| | | | Y110A7A.3.1 |
| | | | CE30706 |
| | | Other_name | lev-7 |
| | | | tmr-3 |
| | | | CELE_Y110A7A.3 | Accession_evidence | NDB | BX284601 |
| | | Public_name | unc-63 |
| | DB_info | Database | AceView | gene | 1F717 |
| | | | WormQTL | gene | WBGene00006797 |
| | | | WormFlux | gene | WBGene00006797 |
| | | | NDB | locus_tag | CELE_Y110A7A.3 |
| | | | Panther | gene | CAEEL|WormBase=WBGene00006797|UniProtKB=Q9N587 |
| | | | | family | PTHR18945 |
| | | | NCBI | gene | 172150 |
| | | | RefSeq | protein | NM_059132.5 |
| | | | SwissProt | UniProtAcc | Q9N587 |
| | | | UniProt_GCRP | UniProtAcc | Q9N587 |
| | | | OMIM | gene | 100690 |
| | | | | | 100710 |
| | | | | | 100720 |
| | | | | | 100725 |
| | | | | | 100730 |
| | | | | | 118502 |
| | | | | | 118503 |
| | | | | | 118504 |
| | | | | | 118507 |
| | Species | Caenorhabditis elegans |
| | History | Version_change | 1 | 07 Apr 2004 11:29:43 | WBPerson1971 | Event | Imported | Initial conversion from geneace |
| | Status | Live |
| Gene_info | Biotype | SO:0001217 |
| | Gene_class | unc |
| | Allele (119) |
| | Legacy_information | e384 : weak kinker thin inactive resistant to 1 mM levamisole sensitive to hypoosmotic shock. ES3 ME2. NA > 50 (x18 etc. : most alleles resemble e384). Also rare exceptional alleles x26 (almost normal movement slight levamisole resistance); b404 (resistant to cholinesterase inhibitor trichlorforn slightly uncoordinated slight levamisole resistance); x33 (more resistant in body than in head). |
| | | See also e214, e215, e384 |
| | | [C.elegansII] e214 : weak kinker, slow, inactive, resistant to 1 mM levamisole, sensitive to hypoosmotic shock; elevated acetylcholine levels. ES3 ME2. OA>50: x13 (pka lev-7, Lev,Ric, poor backing; ES3 ME3), x18, x37 etc. (most alleles resemble e214). Also rare exceptional alleles: x26 (almost normal movement, slight levamisole resistance), b404 (Ric, trichlorfon resistant, slight Lev, slight Unc), x33 (more resistant in body than in head). Previous reference allele "e384" is double with unc-11. [Lewis et al. 1980; Nguyen et al. 1995; AL; RM; TN; ZZ] |
| | Strain (11) |
| | RNASeq_FPKM | WBls:0000002 (78) |
| | | WBls:0000003 (11) |
| | | WBls:0000004 (42) |
| | | WBls:0000006 | 0.674855 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000006.Hermaphrodite.WBbt:0007833.SRP042619.SRX559705 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000006.Hermaphrodite.WBbt:0007833.SRP042619.SRX559706 |
| | | WBls:0000007 | 0.083184 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0006770.SRP045110.SRX666564 |
| | | | 0.202477 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0004015.SRP045110.SRX666563 |
| | | | 0.27589 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0004015.SRP029448.SRX343218 |
| | | | 0.316026 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0004015.SRP045110.SRX666565 |
| | | | 0.329547 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0004015.SRP045110.SRX666567 |
| | | | 0.351723 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0006770.SRP045110.SRX666568 |
| | | | 0.538661 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0006770.SRP045110.SRX666566 |
| | | | 0.561247 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0007833.SRP042619.SRX559707 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0007833.SRP042619.SRX559708 |
| | | | 1.51983 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0004015.SRP029448.SRX343219 |
| | | | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0007833.SRP029448.SRX343215 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0007833.SRP029448.SRX343216 |
| | | WBls:0000008 | 0.334552 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000008.Hermaphrodite.WBbt:0007833.SRP000401.SRX085219 |
| | | | 1.67692 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000008.Hermaphrodite.WBbt:0007833.SRP000401.SRX145480 |
| | | | 1.73592 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000008.Hermaphrodite.WBbt:0007833.SRP000401.SRX085220 |
| | | WBls:0000010 (15) |
| | | WBls:0000013 | 0.165216 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000013.Hermaphrodite.WBbt:0007833.SRP000401.SRX099986 |
| | | | 0.19309 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000013.Hermaphrodite.WBbt:0007833.SRP000401.SRX103652 |
| | | | 0.569526 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000013.Hermaphrodite.WBbt:0007833.SRP000401.SRX1022570 |
| | | | 0.655299 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000013.Hermaphrodite.WBbt:0007833.SRP000401.SRX099996 |
| | | | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000013.Hermaphrodite.WBbt:0007833.SRP000401.SRX099987 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000013.Hermaphrodite.WBbt:0007833.SRP000401.SRX099997 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000013.Hermaphrodite.WBbt:0007833.SRP000401.SRX099998 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000013.Hermaphrodite.WBbt:0007833.SRP000401.SRX1022571 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000013.Hermaphrodite.WBbt:0007833.SRP000401.SRX103653 |
| | | | 3.97835 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000013.Hermaphrodite.WBbt:0007833.SRP000401.SRX1022604 |
| | | | 4.15123 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000013.Hermaphrodite.WBbt:0007833.SRP000401.SRX1022648 |
| | | WBls:0000014 (17) |
| | | WBls:0000015 (24) |
| | | WBls:0000017 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0003810.SRP029448.SRX343324 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0003810.SRP029448.SRX343325 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0004015.SRP029448.SRX343304 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0004015.SRP029448.SRX343305 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0004458.SRP029448.SRX343277 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0004458.SRP029448.SRX343278 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0004804.SRP029448.SRX343252 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0004804.SRP029448.SRX343253 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0004804.SRP029448.SRX343254 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0008115.SRP029448.SRX343342 |
| | | WBls:0000020 (16) |
| | | WBls:0000021 (19) |
| | | WBls:0000023 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000023.Hermaphrodite.WBbt:0007833.SRP015688.SRX185639 |
| | | WBls:0000024 (69) |
| | | WBls:0000027 (15) |
| | | WBls:0000031 | 14.3055 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000031.Hermaphrodite.WBbt:0007833.SRP000401.SRX103273 |
| | | | 14.5614 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000031.Hermaphrodite.WBbt:0007833.SRP000401.SRX103275 |
| | | | 14.7536 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000031.Hermaphrodite.WBbt:0007833.SRP000401.SRX103276 |
| | | | 16.7225 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000031.Hermaphrodite.WBbt:0007833.SRP000401.SRX103274 |
| | | | 20.0079 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000031.Hermaphrodite.WBbt:0007833.SRP000401.SRX103277 |
| | | | 7.74222 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000031.Hermaphrodite.WBbt:0007833.SRP000401.SRX047470 |
| | | | 7.98532 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000031.Hermaphrodite.WBbt:0007833.SRP000401.SRX008139 |
| | | WBls:0000032 | 10.4437 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000032.Hermaphrodite.WBbt:0007833.SRP000401.SRX103983 |
| | | | 10.7554 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000032.Hermaphrodite.WBbt:0007833.SRP000401.SRX103984 |
| | | | 2.9349 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000032.Hermaphrodite.WBbt:0007833.SRP058023.SRX1019179 |
| | | | 3.58621 | From_analysis | RNASeq.elegans.WBls:0000032.control_mean |
| | | | | | RNASeq.elegans.WBls:0000032.control_median |
| | | | 4.23752 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000032.Hermaphrodite.WBbt:0007833.SRP058023.SRX1019178 |
| | | | 4.82496 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000032.Hermaphrodite.WBbt:0007833.SRP000401.SRX008138 |
| | | | 7.11347 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000032.Hermaphrodite.WBbt:0007833.SRP000401.SRX103985 |
| | | WBls:0000035 (26) |
| | | WBls:0000038 (76) |
| | | WBls:0000041 (28) |
| | | WBls:0000052 | 0.34607 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX008140 |
| | | | 11.0615 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX103270 |
| | | | 11.3369 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX103280 |
| | | | 11.4134 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX103272 |
| | | | 11.4969 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX103278 |
| | | | 12.0583 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX103269 |
| | | | 12.1126 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX103281 |
| | | | 13.9862 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX103279 |
| | | | 6.14985 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX037199 |
| | | | 9.03092 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX103271 |
| | | WBls:0000063 (103) |
| | | WBls:0000064 (14) |
| | | WBls:0000065 (16) |
| | | WBls:0000068 | 1.9836 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000068.Hermaphrodite.WBbt:0007833.SRP021083.SRX265364 |
| | | | 2.03621 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000068.Hermaphrodite.WBbt:0007833.SRP021083.SRX265361 |
| | | | 2.29364 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000068.Hermaphrodite.WBbt:0007833.SRP021083.SRX265365 |
| | | | 2.3906 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000068.Hermaphrodite.WBbt:0007833.SRP021083.SRX265360 |
| | | | 2.48624 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000068.Hermaphrodite.WBbt:0007833.SRP021083.SRX265363 |
| | | | 2.62127 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000068.Hermaphrodite.WBbt:0007833.SRP021083.SRX265362 |
| | | WBls:0000131 | 0.844695 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000131.Hermaphrodite.WBbt:0004015.SRP029448.SRX343220 |
| | | | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000131.Hermaphrodite.WBbt:0004015.SRP029448.SRX343227 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000131.Hermaphrodite.WBbt:0004015.SRP029448.SRX343228 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000131.Hermaphrodite.WBbt:0004015.SRP029448.SRX343229 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000131.Hermaphrodite.WBbt:0006771.SRP029448.SRX343225 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000131.Hermaphrodite.WBbt:0006771.SRP029448.SRX343226 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000131.Hermaphrodite.WBbt:0006876.SRP029448.SRX343221 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000131.Hermaphrodite.WBbt:0006876.SRP029448.SRX343222 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000131.Hermaphrodite.WBbt:0006876.SRP029448.SRX343223 |
| | | WBls:0000141 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000141.Hermaphrodite.WBbt:0007833.SRP029448.SRX343161 |
| | | WBls:0000151 | 0.138338 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000151.Hermaphrodite.WBbt:0007833.SRP029448.SRX343162 |
| | | | 1.16904 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000151.Hermaphrodite.WBbt:0004015.SRP029448.SRX343282 |
| | | | 1e-10 | From_analysis (11) |
| | | | 4.4916 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000151.Hermaphrodite.WBbt:0008115.SRP029448.SRX343326 |
| | | WBls:0000171 | 0.280136 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000171.Hermaphrodite.WBbt:0007833.SRP029448.SRX343163 |
| | | | 1e-10 | From_analysis (14) |
| | | WBls:0000181 | 0.418385 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000181.Hermaphrodite.WBbt:0007833.SRP029448.SRX343164 |
| | | WBls:0000191 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000191.Hermaphrodite.WBbt:0007833.SRP029448.SRX343165 |
| | | WBls:0000201 | 1e-10 | From_analysis (12) |
| | | WBls:0000221 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0003810.SRP029448.SRX343314 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0003810.SRP029448.SRX343315 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0004015.SRP029448.SRX343290 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0004015.SRP029448.SRX343291 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0004458.SRP029448.SRX343264 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0004458.SRP029448.SRX343265 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0004458.SRP029448.SRX343266 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0004804.SRP029448.SRX343241 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0008115.SRP029448.SRX343333 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0008115.SRP029448.SRX343334 |
| | | WBls:0000231 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000231.Hermaphrodite.WBbt:0007833.SRP029448.SRX343167 |
| | | WBls:0000251 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0003810.SRP029448.SRX343317 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0004015.SRP029448.SRX343292 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0004458.SRP029448.SRX343268 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0004804.SRP029448.SRX343242 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0004804.SRP029448.SRX343243 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0004804.SRP029448.SRX343244 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0007833.SRP029448.SRX343168 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0008115.SRP029448.SRX343335 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0008115.SRP029448.SRX343336 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0008115.SRP029448.SRX343337 |
| | | WBls:0000261 | 0.482615 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000261.Hermaphrodite.WBbt:0007833.SRP029448.SRX343169 |
| | | WBls:0000281 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000281.Hermaphrodite.WBbt:0007833.SRP029448.SRX343170 |
| | | WBls:0000291 | 1e-10 | From_analysis (12) |
| | | | 5.20712 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0004458.SRP029448.SRX343271 |
| | | WBls:0000301 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000301.Hermaphrodite.WBbt:0007833.SRP029448.SRX343172 |
| | | WBls:0000311 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000311.Hermaphrodite.WBbt:0007833.SRP029448.SRX343173 |
| | | WBls:0000321 | 0.993798 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000321.Hermaphrodite.WBbt:0007833.SRP029448.SRX343174 |
| | | WBls:0000331 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000331.Hermaphrodite.WBbt:0007833.SRP029448.SRX343175 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000331.Hermaphrodite.WBbt:0007833.SRP029448.SRX343176 |
| | | WBls:0000351 | 1.42056 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000351.Hermaphrodite.WBbt:0007833.SRP029448.SRX343178 |
| | | | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000351.Hermaphrodite.WBbt:0007833.SRP029448.SRX343179 |
| | | WBls:0000361 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000361.Hermaphrodite.WBbt:0007833.SRP029448.SRX343180 |
| | | WBls:0000381 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000381.Hermaphrodite.WBbt:0003810.SRP029448.SRX343320 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000381.Hermaphrodite.WBbt:0004015.SRP029448.SRX343297 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000381.Hermaphrodite.WBbt:0004015.SRP029448.SRX343299 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000381.Hermaphrodite.WBbt:0004458.SRP029448.SRX343274 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000381.Hermaphrodite.WBbt:0004458.SRP029448.SRX343275 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000381.Hermaphrodite.WBbt:0004804.SRP029448.SRX343248 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000381.Hermaphrodite.WBbt:0004804.SRP029448.SRX343249 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000381.Hermaphrodite.WBbt:0004804.SRP029448.SRX343250 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000381.Hermaphrodite.WBbt:0008115.SRP029448.SRX343340 |
| | | WBls:0000391 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000391.Hermaphrodite.WBbt:0007833.SRP029448.SRX343181 |
| | | WBls:0000401 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000401.Hermaphrodite.WBbt:0007833.SRP029448.SRX343182 |
| | | WBls:0000421 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000421.Hermaphrodite.WBbt:0007833.SRP029448.SRX343184 |
| | | WBls:0000431 | 0.458385 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000431.Hermaphrodite.WBbt:0007833.SRP029448.SRX343185 |
| | | WBls:0000451 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000451.Hermaphrodite.WBbt:0007833.SRP029448.SRX343186 |
| | | WBls:0000461 | 0.248373 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000461.Hermaphrodite.WBbt:0007833.SRP029448.SRX343187 |
| | | WBls:0000471 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000471.Hermaphrodite.WBbt:0004015.SRP029448.SRX343300 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000471.Hermaphrodite.WBbt:0004015.SRP029448.SRX343301 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000471.Hermaphrodite.WBbt:0004015.SRP029448.SRX343302 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000471.Hermaphrodite.WBbt:0004458.SRP029448.SRX343276 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000471.Hermaphrodite.WBbt:0004804.SRP029448.SRX343251 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000471.Hermaphrodite.WBbt:0007833.SRP029448.SRX343189 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000471.Hermaphrodite.WBbt:0008115.SRP029448.SRX343341 |
| | | WBls:0000491 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000491.Hermaphrodite.WBbt:0007833.SRP029448.SRX343191 |
| | | WBls:0000501 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000501.Hermaphrodite.WBbt:0007833.SRP029448.SRX343192 |
| | | WBls:0000511 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000511.Hermaphrodite.WBbt:0007833.SRP029448.SRX343194 |
| | | WBls:0000521 | 1.22303 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000521.Hermaphrodite.WBbt:0007833.SRP029448.SRX343195 |
| | | WBls:0000531 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000531.Hermaphrodite.WBbt:0007833.SRP029448.SRX343196 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000531.Hermaphrodite.WBbt:0007833.SRP029448.SRX343197 |
| | | WBls:0000541 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000541.Hermaphrodite.WBbt:0007833.SRP029448.SRX343198 |
| | | | 3.42268 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000541.Hermaphrodite.WBbt:0007833.SRP029448.SRX343199 |
| | | WBls:0000551 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000551.Hermaphrodite.WBbt:0007833.SRP029448.SRX343200 |
| | | WBls:0000561 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000561.Hermaphrodite.WBbt:0007833.SRP029448.SRX343201 |
| | | WBls:0000581 | 0.631441 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000581.Hermaphrodite.WBbt:0007833.SRP029448.SRX343202 |
| | | WBls:0000621 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000621.Hermaphrodite.WBbt:0007833.SRP029448.SRX343203 |
| | | WBls:0000674 | 0.772419 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000674.Hermaphrodite.WBbt:0007833.SRP021083.SRX265366 |
| | | | 1.7327 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000674.Hermaphrodite.WBbt:0007833.SRP021083.SRX265369 |
| | | | 1.99701 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000674.Hermaphrodite.WBbt:0007833.SRP021083.SRX265371 |
| | | | 2.47558 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000674.Hermaphrodite.WBbt:0007833.SRP021083.SRX265370 |
| | | | 2.65746 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000674.Hermaphrodite.WBbt:0007833.SRP021083.SRX265368 |
| | | | 2.68632 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000674.Hermaphrodite.WBbt:0007833.SRP021083.SRX265367 |
| | | WBls:0000676 | 2.1431 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000676.Hermaphrodite.WBbt:0007833.SRP021083.SRX265372 |
| | | | 3.06307 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000676.Hermaphrodite.WBbt:0007833.SRP021083.SRX265374 |
| | | | 3.34784 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000676.Hermaphrodite.WBbt:0007833.SRP021083.SRX265375 |
| | | | 3.38451 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000676.Hermaphrodite.WBbt:0007833.SRP021083.SRX265373 |
| | | WBls:0000694 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000694.Hermaphrodite.WBbt:0007833.SRP029448.SRX343205 |
| | | WBls:0000695 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000695.Hermaphrodite.WBbt:0007833.SRP029448.SRX343206 |
| | | WBls:0000696 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000696.Hermaphrodite.WBbt:0007833.SRP029448.SRX343207 |
| | | WBls:0000697 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000697.Hermaphrodite.WBbt:0007833.SRP029448.SRX343208 |
| | | WBls:0000699 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000699.Hermaphrodite.WBbt:0007833.SRP029448.SRX343210 |
| | | WBls:0000700 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000700.Hermaphrodite.WBbt:0007833.SRP029448.SRX343211 |
| | | WBls:0000701 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000701.Hermaphrodite.WBbt:0007833.SRP029448.SRX343212 |
| | | WBls:0000702 | 4.41319 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000702.Hermaphrodite.WBbt:0007833.SRP029448.SRX343213 |
| | | WBls:0000703 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000703.Hermaphrodite.WBbt:0007833.SRP029448.SRX343214 |
| | GO_annotation (42) |
| | Ortholog (59) |
| | Paralog (100) |
| | Structured_description | Concise_description | unc-63 encodes an alpha subunit of a levamisole-sensitive nicotinic acetylcholine receptor (L-nAChR); UNC-63 is required for normal locomotion and regulation of egg-laying behavior, and functions as a subunit of a ligand-gated ion channel that likely mediates fast actions of acetylcholine at neuromuscular junctions and in the nervous system; when coexpressed with UNC-29 and LEV-1, non-alpha L-nAChR subunits, the resulting multimer can form levamisole-gated channels; UNC-63 is expressed in body wall muscles, vulval muscles, and a large number of ventral cord neurons; UNC-63 is a member of the UNC-38-like group of nAChR subunits. | Paper_evidence | WBPaper00000031 |
| | | | | | WBPaper00004660 |
| | | | | | WBPaper00005223 |
| | | | | | WBPaper00005594 |
| | | | | | WBPaper00024530 |
| | | | | | WBPaper00037697 |
| | | | | Curator_confirmed | WBPerson1843 |
| | | | | Date_last_updated | 07 Dec 2011 00:00:00 |
| | | Automated_description | Enables acetylcholine-gated monoatomic cation-selective channel activity. Involved in several processes, including calcium ion import across plasma membrane; cholinergic synaptic transmission; and regulation of multicellular organismal process. Located in neuromuscular junction and postsynaptic membrane. Expressed in ganglia; head muscle; motor neurons; non-striated muscle; and ventral nerve cord. Used to study alcohol use disorder and congenital myasthenic syndrome. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; autosomal dominant nocturnal frontal lobe epilepsy (multiple); congenital myasthenic syndrome (multiple); and lung disease (multiple). Is an ortholog of human CHRNA2 (cholinergic receptor nicotinic alpha 2 subunit); CHRNA3 (cholinergic receptor nicotinic alpha 3 subunit); and CHRNA6 (cholinergic receptor nicotinic alpha 6 subunit). | Paper_evidence | WBPaper00065943 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | | WBPerson37462 |
| | | | | Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase |
| | | | | Date_last_updated | 29 Nov 2023 00:00:00 |
| Disease_info | Experimental_model | DOID:1574 | Homo sapiens | Paper_evidence | WBPaper00045914 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | Date_last_updated | 06 Jun 2019 00:00:00 |
| | | DOID:3635 | Homo sapiens | Paper_evidence | WBPaper00037697 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | Date_last_updated | 23 Feb 2021 00:00:00 |
| | Potential_model (29) |
| Models_disease_asserted | WBDOannot00000705 |
| | WBDOannot00000706 |
| | WBDOannot00000869 |
| | WBDOannot00000870 |
| | WBDOannot00000871 |
| | WBDOannot00000872 |
| | WBDOannot00000873 |
| | WBDOannot00000874 |
| | WBDOannot00000875 |
| Molecular_info | Corresponding_CDS | Y110A7A.3 |
| | Corresponding_transcript | Y110A7A.3.1 |
| | Other_sequence (49) |
| | Associated_feature | WBsf983609 |
| | | WBsf983610 |
| | | WBsf983611 |
| | | WBsf983612 |
| | | WBsf1009773 |
| | | WBsf1009774 |
| | | WBsf1009775 |
| | | WBsf217630 |
| Experimental_info | RNAi_result | WBRNAi00004530 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00066522 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00089742 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00066395 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00090027 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00090345 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00055324 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00090186 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00036556 | Inferred_automatically | RNAi_primary |
| | Expr_pattern | Chronogram2008 |
| | | Expr3394 |
| | | Expr3926 |
| | | Expr6882 |
| | | Expr10821 |
| | | Expr1018874 |
| | | Expr1032867 |
| | | Expr1158864 |
| | | Expr2017896 |
| | | Expr2036032 |
| | Drives_construct | WBCnstr00000877 |
| | | WBCnstr00003643 |
| | | WBCnstr00006476 |
| | | WBCnstr00006477 |
| | | WBCnstr00008276 |
| | | WBCnstr00009871 |
| | | WBCnstr00011375 |
| | | WBCnstr00011753 |
| | | WBCnstr00017749 |
| | Construct_product | WBCnstr00000877 |
| | | WBCnstr00006476 |
| | | WBCnstr00006477 |
| | | WBCnstr00006571 |
| | | WBCnstr00007478 |
| | | WBCnstr00008274 |
| | | WBCnstr00008275 |
| | | WBCnstr00008276 |
| | | WBCnstr00008277 |
| | | WBCnstr00008278 |
| | | WBCnstr00011753 |
| | | WBCnstr00018657 |
| | Antibody | WBAntibody00001429 |
| | | WBAntibody00002210 |
| | Microarray_results (18) |
| | Expression_cluster (112) |
| | Interaction | WBInteraction000164160 |
| | | WBInteraction000503664 |
| | | WBInteraction000518472 |
| | | WBInteraction000518495 |
| | | WBInteraction000536782 |
| | | WBInteraction000540194 |
| | | WBInteraction000541906 |
| | | WBInteraction000541922 |
| | | WBInteraction000543440 |
| Map_info | Map | I | Position | -0.35206 |
| | Well_ordered |
| | Positive | Positive_clone | Y72E2 |
| | | | Y110A7A | Inferred_automatically | From sequence, transcript, pseudogene data |
| | Mapping_data | 2_point | 9 |
| | | | 209 |
| | | | 210 |
| | | | 245 |
| | | | 246 |
| | | | 410 |
| | | | 614 |
| | | | 2501 |
| | | Multi_point (11) |
| | | Pos_neg_data (16) |
| Reference (119) |
| Remark | Sequence connection from [Culetto E, Sattelle DB] (via JAH) |
| | [140923 pad] Modified Map position as it was a reverse physical that could not be fixed by automated methods. |
| Method | Gene |
