WormBase Tree Display for Gene: WBGene00006822

WBGene00006822 SMap: S_parent: Sequence: C46F11
  Identity: Version: 1
    Name: CGC_name: unc-93 Person_evidence: WBPerson261
      Sequence_name: C46F11.1
      Molecular_name: C46F11.1a
        C46F11.1a.1
        CE30906
        C46F11.1b
        CE37957
        C46F11.1b.1
      Other_name: CELE_C46F11.1 Accession_evidence: NDB BX284603
      Public_name: unc-93
    DB_info: Database: WormQTL gene WBGene00006822
        WormFlux gene WBGene00006822
        NDB locus_tag CELE_C46F11.1
        Panther gene CAEEL|WormBase=WBGene00006822|UniProtKB=Q93380
          family PTHR19444
        NCBI gene 175466
        RefSeq protein NM_001026047.5
            NM_001381807.1
        SwissProt UniProtAcc Q93380
        TREEFAM TREEFAM_ID TF314905
        UniProt_GCRP UniProtAcc Q93380
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:43 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: unc
    Reference_allele: WBVar00144047
    Allele (189)
    Legacy_information (4)
    Strain (31)
    RNASeq_FPKM (74)
    GO_annotation (16)
    Ortholog: WBGene00054840 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00031294 Caenorhabditis briggsae From_analysis: OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00134386 Caenorhabditis japonica From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00192027 Caenorhabditis brenneri From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00110862 Pristionchus pacificus From_analysis: Inparanoid_8
      WBGene00232469 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g6684 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g15155 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g3790 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g71 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g962 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g25680 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g1286 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g18834 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g1730 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g8154 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00243.g7744 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-unc-93 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Cnig_chr_III.g10500 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold629.g9500 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00081.g3655 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_10288 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_009704 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g02194 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g15210 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_30220500 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIII_pilon.g7286 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00248237 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00273770 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00266883 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00286260 Trichuris muris From_analysis: WormBase-Compara
      WBGene00300193 Trichuris muris From_analysis: WormBase-Compara
      FB:FBgn0027556 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      FB:FBgn0033289 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-041014-304 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:12570 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1933250 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:3712668 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1583290 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Structured_description: Concise_description: unc-93 encodes a novel transmembrane protein that affects muscle contraction and egg laying; UNC-93 is predicted to be a component of a multi-protein complex containing the SUP-9 two-pore potassium channel and the SUP-10 transmembrane protein; an UNC-93::GFP fusion protein is expressed in body wall muscle membranes and dense bodies as well as in the vulval and intestinal muscles; neuronal UNC-93::GFP expression is found in the four SIA neurons that originate in the head, receive some synapses in the nerve ring, and extend posteriorly directed processes; in muscle cells, UNC-93::GFP colocalizes with SUP-9 to dense bodies and membranes. Paper_evidence: WBPaper00000486
            WBPaper00000564
            WBPaper00001525
            WBPaper00001800
            WBPaper00006135
          Curator_confirmed: WBPerson1843
            WBPerson324
          Date_last_updated: 26 Jun 2008 00:00:00
      Automated_description: Enables potassium channel regulator activity. Involved in regulation of muscle contraction and regulation of potassium ion transport. Located in plasma membrane and striated muscle dense body. Expressed in SIA; body wall musculature; and non-striated muscle. Is an ortholog of human UNC93A (unc-93 homolog A). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C46F11.1a
      C46F11.1b
    Corresponding_CDS_history: C46F11.1:wp80
      C46F11.1:wp138
      C46F11.1:wp140
    Corresponding_transcript: C46F11.1a.1
      C46F11.1b.1
    Other_sequence: FE914682.1
      FE913923.1
      Dviv_isotig29800
      ASC31488_1
      JI167429.1
    Associated_feature: WBsf991851
      WBsf991852
      WBsf991853
      WBsf991854
      WBsf224634
  Experimental_info: RNAi_result (12)
    Expr_pattern: Expr2773
      Expr2775
      Expr1019911
      Expr1032886
      Expr1146588
      Expr2017919
      Expr2036055
    Drives_construct (19)
    Construct_product (23)
    Microarray_results (23)
    Expression_cluster (85)
    Interaction (54)
  Map_info: Map: III Position: -5.0882 Error: 0.020586
    Well_ordered
    Positive: Inside_rearr: nDf6
        nDf7
        nDf8
        nDf10
        nDf11
        nDf12
        nDf13
        nDf14
        nDf15
      Positive_clone: C46F11 Inferred_automatically: From sequence, transcript, pseudogene data
        MT#JL932
    Mapping_data: 2_point: 402
        403
        6037
        6039
        6040
      Multi_point (46)
      Pos_neg_data (11)
    Landmark_gene
  Reference (114)
  Method: Gene