| WBGene00006824 | Evidence | Paper_evidence | WBPaper00019431 |
|---|
| SMap | S_parent | Sequence | Y105E8A |
| Identity | Version | 1 |
| | Name | CGC_name | unc-95 | Person_evidence | WBPerson261 |
| | | Sequence_name | Y105E8A.6 |
| | | Molecular_name | Y105E8A.6 |
| | | | Y105E8A.6.1 |
| | | | CE31857 |
| | | Other_name | Y105E8E.e | Curator_confirmed | WBPerson1983 |
| | | | | Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs |
| | | | CELE_Y105E8A.6 | Accession_evidence | NDB | BX284601 |
| | | Public_name | unc-95 |
| | DB_info | Database | AceView | gene | 1O974 |
| | | | WormQTL | gene | WBGene00006824 |
| | | | WormFlux | gene | WBGene00006824 |
| | | | NDB | locus_tag | CELE_Y105E8A.6 |
| | | | NCBI | gene | 173301 |
| | | | RefSeq | protein | NM_170938.7 |
| | | | SwissProt | UniProtAcc | Q9NEZ5 |
| | | | UniProt_GCRP | UniProtAcc | Q9NEZ5 |
| | Species | Caenorhabditis elegans |
| | History | Version_change | 1 | 07 Apr 2004 11:29:43 | WBPerson1971 | Event | Imported | Initial conversion from geneace |
| | Status | Live |
| Gene_info | Biotype | SO:0001217 |
| | Gene_class | unc |
| | Allele (65) |
| | Legacy_information | su106sd : very slow or paralysed Egl; abnormal variable muscle birefringence disorganized sarcomeres with collections of thin filaments. ES3. NA4 (su33amber (simialr phenotypes ME0) etc.). |
| | | [C.elegansII] su106sd : very slow or paralysed, Egl; abnormal variable muscle birefringence, disorganized sarcomeres with collections of thin filaments. ES3. OA3: su33amb (similar phenotypes, ME0), etc. [Zengel and Epstein 1980; HE] |
| | Strain (2) |
| | RNASeq_FPKM (74) |
| | GO_annotation (20) |
| | Ortholog (29) |
| | Paralog | WBGene00000438 | Caenorhabditis elegans | From_analysis | WormBase-Compara |
| | | WBGene00002987 | Caenorhabditis elegans | From_analysis | WormBase-Compara |
| | | WBGene00002988 | Caenorhabditis elegans | From_analysis | WormBase-Compara |
| | | WBGene00003000 | Caenorhabditis elegans | From_analysis | WormBase-Compara |
| | | WBGene00003167 | Caenorhabditis elegans | From_analysis | WormBase-Compara |
| | | WBGene00006654 | Caenorhabditis elegans | From_analysis | WormBase-Compara |
| | | WBGene00015216 | Caenorhabditis elegans | From_analysis | WormBase-Compara |
| | | WBGene00017644 | Caenorhabditis elegans | From_analysis | WormBase-Compara |
| | | WBGene00022518 | Caenorhabditis elegans | From_analysis | WormBase-Compara |
| | Structured_description | Concise_description | unc-95 encodes a LIM domain-containing protein related to Drosophila and vertebrate paxillins; UNC-95 is required for locomotion and organization of thick and thin filaments in body wall muscle; by homology, UNC-95 may function as an anchor protein that links signaling and cytoskeletal proteins at focal adhesions; in vitro, UNC-95 interacts with RNF-5, a RING finger protein that may function as an E3 ligase to regulate UNC-95 levels via ubiquitin-mediated degradation; UNC-95 is expressed in body-wall and vulval muscles, and co-localizes with RNF-5 to muscle dense bodies (focal adhesion-like attachment sites). | Paper_evidence | WBPaper00000488 |
| | | | | | WBPaper00013295 |
| | | | | | WBPaper00019431 |
| | | | | Curator_confirmed | WBPerson1843 |
| | | | | Date_last_updated | 17 Jun 2004 00:00:00 |
| | | Automated_description | Enables protein domain specific binding activity. Located in M band; nucleus; and striated muscle dense body. | Paper_evidence | WBPaper00065943 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | | WBPerson37462 |
| | | | | Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase |
| | | | | Date_last_updated | 29 Nov 2023 00:00:00 |
| Molecular_info | Corresponding_CDS | Y105E8A.6 |
| | Corresponding_CDS_history | Y105E8A.6:wp86 |
| | Corresponding_transcript | Y105E8A.6.1 |
| | Other_sequence (34) |
| | Associated_feature | WBsf649756 |
| | | WBsf665123 |
| | | WBsf979068 |
| | | WBsf986146 |
| | | WBsf986147 |
| | | WBsf1011238 |
| | | WBsf220605 |
| | | WBsf220606 |
| | | WBsf220607 |
| | | WBsf220608 |
| | Transcription_factor | WBTranscriptionFactor000438 |
| Experimental_info | RNAi_result (13) |
| | Expr_pattern | Expr2991 |
| | | Expr2992 |
| | | Expr8314 |
| | | Expr8542 |
| | | Expr1012404 |
| | | Expr1032888 |
| | | Expr1158771 |
| | | Expr2017921 |
| | | Expr2036057 |
| | Drives_construct | WBCnstr00006034 |
| | | WBCnstr00011070 |
| | | WBCnstr00011071 |
| | | WBCnstr00013356 |
| | | WBCnstr00034135 |
| | Construct_product | WBCnstr00006034 |
| | | WBCnstr00013356 |
| | | WBCnstr00034135 |
| | Regulate_expr_cluster | WBPaper00031097:unc-95(su33)_upregulated |
| | Antibody | WBAntibody00001286 |
| | Microarray_results (18) |
| | Expression_cluster | WBPaper00028451:Oogenic_protein |
| | | WBPaper00031040:TGF-beta_adult_upregulated |
| | | WBPaper00037047:aging_accelerated_insoluble_protein |
| | | WBPaper00037047:insoluble_protein |
| | | WBPaper00037950:bodywall-muscle_CoreEnriched |
| | | WBPaper00037950:bodywall-muscle_embryo_enriched |
| | | WBPaper00037950:bodywall-muscle_embryo_SelectivelyEnriched |
| | | WBPaper00037950:bodywall-muscle_larva_enriched |
| | | WBPaper00037950:bodywall-muscle_larva_SelectivelyEnriched |
| | | WBPaper00038168:lin-35_downregulated |
| | | WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq |
| | | WBPaper00044128:daf-2(e1370)_upregulated |
| | | WBPaper00044316:CH3HgCl_7.5uM_downregulated |
| | | WBPaper00044501:gld-1_let-7_regulated |
| | | WBPaper00044578:reduced-humidity_downregulated_microarray |
| | | WBPaper00044736:flat_dev_expression |
| | | WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated |
| | | WBPaper00045417:128Q-huntingtin_upreglated |
| | | WBPaper00045521:Spermatogenic |
| | | WBPaper00046121:mesoderm_unique |
| | | WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h |
| | | WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h |
| | | WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h |
| | | WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h |
| | | WBPaper00046499:AMPK_regulated |
| | | WBPaper00048952:glucose_induced |
| | | WBPaper00048988:neuron_expressed |
| | | WBPaper00049217:TCER-1_downregulated |
| | | WBPaper00049498:npr-1(ur89)_regulated_3 |
| | | WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031) |
| | | WBPaper00049920:Glucose-Diet_upregulated_N2 |
| | | WBPaper00049942:HeatShock_upregulated_hsf-1(+) |
| | | WBPaper00050053:muscle_enriched_Day4 |
| | | WBPaper00050053:muscle_enriched_Day12 |
| | | WBPaper00050163:let-418(RNAi)_downregulated_100-cell-embryo |
| | | WBPaper00050344:AFD-neuron_enriched |
| | | WBPaper00050344:PLM-neuron_enriched |
| | | WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C |
| | | WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_dauer_20C |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult |
| | | WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult |
| | | WBPaper00050990:arcade_intestinal-valve_expressed |
| | | WBPaper00050990:GABAergic-neuron_expressed |
| | | WBPaper00050990:hypodermis_expressed |
| | | WBPaper00051245:body-wall-muscle_cytoplasm_expressed |
| | | WBPaper00051245:body-wall-muscle_specific |
| | | WBPaper00051245:cytoplasm_specific |
| | | WBPaper00052884:emb-4(hc60)_upregulated |
| | | WBPaper00053184:sma-4(rax3)_upregulated |
| | | WBPaper00053302:stavudine_24h_regulated |
| | | WBPaper00053321:PGCs_depleted_NuGen |
| | | WBPaper00053388:dauer_regulated_Cluster5 |
| | | WBPaper00055354:eat-2(ad1116)_upregulated |
| | | WBPaper00055482:Tunicamycin_downregulated |
| | | WBPaper00055648:male-vas-deferens_expressed |
| | | WBPaper00055827:pfd-6(gk493446)_downregulated |
| | | WBPaper00055971:nhl-2(ok818)_20C_downregulated |
| | | WBPaper00055971:nhl-2(ok818)_25C_downregulated |
| | | WBPaper00056034:pals-22(jy3)_upregulated |
| | | WBPaper00056139:soil-microbiota_upregulated |
| | | WBPaper00056161:male_enriched_siRNA |
| | | WBPaper00056169:rrf-3(pk1426)_upregulated_embryo |
| | | WBPaper00056443:DietaryRestriction_downregulated |
| | | WBPaper00056471:S.aureus-4h_downregulated_N2 |
| | | WBPaper00056826:hmc_biased |
| | | WBPaper00056900:TOFU-6_interacting |
| | | WBPaper00057041:unc-70(cas983)_upregulated |
| | | WBPaper00057154:HeatShock_upregulated_mRNA |
| | | WBPaper00057288:Cold_downregulated_transcript |
| | | WBPaper00058598:mex-1(or286)_upregulated |
| | | WBPaper00058598:mex-3(eu149)_upregulated |
| | | WBPaper00058598:sin-3(tm1276)_downregulated |
| | | WBPaper00058958:100mGy-irradiation-72h_upregulated |
| | | WBPaper00059664:srbc-48(ac23)_upregulated |
| | | WBPaper00059895:wounding_downregulated |
| | | WBPaper00060014:set-2(tm1630)_downregulated |
| | | WBPaper00060358:B.thuringiensis_pathogen_regulated_N2 |
| | | WBPaper00060526:plp-1(ok2155)_upregulated |
| | | WBPaper00060683:hlh-11(ko1)_upregulated |
| | | WBPaper00060703:nas-38(ok3407)_downregulated |
| | | WBPaper00061203:sin-3(tm1276)_upregulated |
| | | WBPaper00061203:spr-1(ok2144)_upregulated |
| | | WBPaper00061340:BWM_anterior |
| | | WBPaper00061340:BWM_far_posterior |
| | | WBPaper00061340:mu_int_mu_anal |
| | | WBPaper00061340:mu_sph |
| | | WBPaper00061341:28C_24h_downregulated |
| | | WBPaper00061479:mep-1(ne4629)_upregulated |
| | | WBPaper00061527:myo-3-Y71G12B.11_22540 |
| | | WBPaper00061818:ELKS-1_interacting |
| | | WBPaper00062159:hda-2(ok1479)_upregulated |
| | | WBPaper00062325:muscle_enriched_coding-RNA |
| | | WBPaper00062498:PPM-1.D_interacting |
| | | WBPaper00064005:starvation_downregulated_aptf-1(gk794)_mRNA |
| | | WBPaper00064071:NHR-49_interacting |
| | | WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20) |
| | | WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141) |
| | | WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20) |
| | | WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141) |
| | | WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated |
| | | WBPaper00064306:Agaro-oligosaccharides_upregulated |
| | | WBPaper00064716:paraquat_downregulated |
| | | WBPaper00064727:daf-2(e1370)_upregulated |
| | | WBPaper00065032:PAO1_vs_Delt.Pf4-infection_downregulated |
| | | WBPaper00065096:Day10_vs_Day1_downregulated |
| | | WBPaper00065373:Cisplatin_upregulated_WT |
| | | WBPaper00065373:sek-1(km4)_upregulated_Ref |
| | | WBPaper00065835:Day5_vs_Day1_downregulated |
| | | WBPaper00065835:Day11_vs_Day1_downregulated |
| | | WBPaper00065841:1_1 |
| | | WBPaper00065841:7_3 |
| | | WBPaper00065841:7_4 |
| | | WBPaper00065841:15_0 |
| | | WBPaper00065841:96_0 |
| | | WBPaper00065841:143_0 |
| | | WBPaper00065975:P-body_vs_oocyte_depleted |
| | | WBPaper00065975:P-body_vs_WholeAnimal_depleted |
| | | WBPaper00065993:glp-1(e2141)_upregulated |
| | | WBPaper00065995:M.humicola-extract_upregulated_old-1(ok1273) |
| | | WBPaper00066085:sin-3(tm1276)_upregulated |
| | | WBPaper00066110:Doxorubicin_upregulated_diploid |
| | | WBPaper00066110:tetraploid_vs_diploid_upregulated |
| | | WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14 |
| | | cgc4386_cluster_6_6 |
| | | cgc4489_group_8 |
| | | WBPaper00005124:cholesterol_10-9M_regulated |
| | | WBPaper00025141:N2_Expressed_Genes |
| | | WBPaper00031003:0hr_muscle_enriched |
| | | WBPaper00031003:24hr_muscle_enriched |
| | | WBPaper00031003:hlh_1_enriched |
| | | WBPaper00031003:total_muscle_enriched |
| | | WBPaper00032948:FedUp |
| | | WBPaper00035873:dpy-9_regulated |
| | | WBPaper00035873:dpy-10_regulated |
| | | WBPaper00036286:Pattern_C |
| | | WBPaper00038231:Cry5B_1.5-fold_downregulated |
| | | WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated |
| | | WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2 |
| | | WBPaper00040876:mir-35_downregulated |
| | | WBPaper00040963:Q100_down |
| | | WBPaper00040963:Q200_down |
| | | WBPaper00040963:TA300_up |
| | | WBPaper00041002:HF_3d_0.2mM_Up |
| | | WBPaper00041002:HF_3d_2.0mM_Up |
| | | WBPaper00041606:CE_X.nematophila_regulated |
| | | WBPaper00041939:control_vs_EtBr-exposed_48h |
| | | WBPaper00041939:control_vs_UVC-EtBr-exposed_48h |
| | | WBPaper00041939:control_vs_UVC-EtBr-exposed_51h |
| | | WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h |
| | | WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_51h |
| | | WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h |
| | | WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h |
| | | WBPaper00045263:isp-1(qm150)_upregulated |
| | | WBPaper00048989:eat-2(ad465)_rapamycin_upregulated |
| | | [cgc6390]:Cluster_C |
| | Interaction (56) |
| | WBProcess | WBbiopr:00000006 |
| Map_info | Map | I | Position | 24.674 | Error | 0.00615 |
| | Well_ordered |
| | Positive | Positive_clone | Y105E8A | Inferred_automatically | From sequence, transcript, pseudogene data |
| | Mapping_data | 2_point | 392 |
| | | | 393 |
| | | | 394 |
| | | | 3684 |
| | | | 3685 |
| | | | 7080 |
| | | Multi_point | 2332 |
| | | | 4894 |
| | | Pos_neg_data | 5109 |
| | | | 5110 |
| | | | 5111 |
| | | | 5112 |
| | | | 5113 |
| | | | 5114 |
| | | | 5115 |
| Reference (31) |
| Method | Gene |
