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WormBase Tree Display for Gene: WBGene00006839

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Name Class

WBGene00006839SMapS_parentSequenceF09B9
IdentityVersion1
NameCGC_nameunc-115Person_evidenceWBPerson261
Sequence_nameF09B9.2
Molecular_nameF09B9.2a
F09B9.2a.1
CE15759
F09B9.2b
CE02176
F09B9.2b.1
Other_nameCELE_F09B9.2Accession_evidenceNDBBX284606
Public_nameunc-115
DB_infoDatabaseAceViewgeneXK771
WormQTLgeneWBGene00006839
WormFluxgeneWBGene00006839
NDBlocus_tagCELE_F09B9.2
PanthergeneCAEEL|WormBase=WBGene00006839|UniProtKB=Q95QM5
familyPTHR24213
NCBIgene181227
RefSeqproteinNM_077301.9
NM_001029371.8
TREEFAMTREEFAM_IDTF318042
TrEMBLUniProtAccQ95QM5
Q19240
UniProt_GCRPUniProtAccQ95QM5
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:43WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classunc
Allele (111)
Legacy_informationSee also e2225
[C.elegansII] e2225mut : uncoordinated movement, severe kinker. Muscle structure appears normal. OA1: mn481. Cloned: predicted protein has N-term LIMb domain, C-term villin headpiece similarity. [FF; SP]
StrainWBStrain00003646
WBStrain00027092
WBStrain00030542
WBStrain00034392
WBStrain00034399
WBStrain00037520
WBStrain00005032
WBStrain00005254
RNASeq_FPKM (74)
GO_annotation (16)
Ortholog (39)
Structured_descriptionConcise_descriptionunc-115 encodes a protein that binds actin filaments and that is required for RAS signalling and UNC-40/netrin activity during axon pathfinding.Paper_evidenceWBPaper00005607
WBPaper00005719
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionEnables actin filament binding activity. Involved in neuron projection morphogenesis; regulation of filopodium assembly; and regulation of lamellipodium assembly. Located in basal plasma membrane and cytoplasm. Expressed in several structures, including PDE; excretory cell; pharynx; somatic nervous system; and vulva. Is an ortholog of human ABLIM2 (actin binding LIM protein family member 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF09B9.2a
F09B9.2b
Corresponding_transcriptF09B9.2a.1
F09B9.2b.1
Other_sequence (45)
Associated_feature (16)
Transcription_factorWBTranscriptionFactor000712
Experimental_infoRNAi_result (17)
Expr_pattern (11)
Drives_construct (12)
Construct_productWBCnstr00007698
WBCnstr00018995
WBCnstr00020818
WBCnstr00034126
AntibodyWBAntibody00001164
Microarray_results (29)
Expression_clusterWBPaper00029359_1142
WBPaper00029359_1217
WBPaper00029359_1280
WBPaper00029359_1444
WBPaper00029359_1504
WBPaper00029359_1604
WBPaper00031040:TGF-beta_adult_upregulated
WBPaper00032528:L3_enriched
WBPaper00032976:dosage_compensated_genes
WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
WBPaper00037950:BAG-neuron_blastula-embryo_expressed
WBPaper00037950:bodywall-muscle_L1-larva_expressed
WBPaper00037950:coelomocytes_L2-larva_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
WBPaper00040221:DAF-12_target_ALF4
WBPaper00041222:hlh-1(cc561)_upregulated
WBPaper00041222:unc-120(st364)_downregulated
WBPaper00044736:flat_dev_expression
WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
WBPaper00045420:fertilization_downregulated_transcript
WBPaper00045521:Gender_Neutral
WBPaper00045974:NSM_enriched_totalRNA_RNAseq
WBPaper00048988:neuron_enriched
WBPaper00048988:neuron_expressed
WBPaper00049498:npr-1(ur89)_regulated_3
WBPaper00049545:cco-1(RNAi)_upregulated
WBPaper00049545:jmjd-3.1(+)_upregulated
WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
WBPaper00049626:UNC-75_target
WBPaper00050344:AFD-neuron_enriched
WBPaper00050344:ASER-neuron_enriched
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050859:upregulated_glh-1(gk100)_vs_control_day1-adult
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
WBPaper00050990:arcade_intestinal-valve_expressed
WBPaper00050990:body-muscle_expressed
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00050990:intestine_expressed
WBPaper00050990:NMDA-neuron_expressed
WBPaper00050990:pharynx_expressed
WBPaper00050990:seam_expressed
WBPaper00051039:ash-2(RNAi)_regulated_intestine
WBPaper00051245:body-wall-muscle_cytoplasm_expressed
WBPaper00051245:body-wall-muscle_nucleus_expressed
WBPaper00051245:cytoplasm_specific
WBPaper00051245:epidermis_cytoplasm_expressed
WBPaper00051245:epidermis_nucleus_expressed
WBPaper00051245:intestine_cytoplasm_expressed
WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed
WBPaper00051352:Long-Term-Association-Memory_upregulated
WBPaper00051404:alg-1(gk214)_upregulated
WBPaper00052884:emb-4(hc60)_upregulated
WBPaper00053184:sma-4(rax3)_upregulated
WBPaper00053295:lin-22(icb38)_upregulated
WBPaper00053302:zidovudine_72h_regulated
WBPaper00053321:embryo-to-L1_downregulated_WT_SMARTseq
WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_L1_SMARTseq
WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_starved-L1_Truseq
WBPaper00053321:PGCs_depleted_NuGen
WBPaper00053388:dauer_regulated_Cluster1
WBPaper00053599:oocyte_vs_mitosis_downregulated
WBPaper00053810:isp-1(qm150)_downregulated
WBPaper00054758:alg-1(gk204)_upregulated
WBPaper00055334:DLC-1_interacting
WBPaper00055354:Psora-Allantoin_downregulated
WBPaper00055354:Rapamycin-Allantoin_downregulated
WBPaper00055354:Rapamycin-Metformin_downregulated
WBPaper00055354:Rifampicin-Allantoin_downregulated
WBPaper00055565:AVK_enriched
WBPaper00056034:pals-22(jy3)_upregulated
WBPaper00056443:DietaryRestriction_downregulated
WBPaper00056443:sek-1(km4)_upregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
WBPaper00056826:hmc_biased
WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
WBPaper00058598:mex-3(eu149)_upregulated
WBPaper00058598:sin-3(tm1276)_downregulated
WBPaper00058725:sftb-1(cer6)_downregulated
WBPaper00058958:100mGy-irradiation-72h_upregulated
WBPaper00059027:neuron-synapses_depleted
WBPaper00059356:BAZ-2_SET-6_interacting
WBPaper00059471:EGL-43_interacting
WBPaper00059664:srbc-48(ac23)_upregulated
WBPaper00059763:neuron_expressed
WBPaper00059824:rnp-6(dh1127)_regulated_OP50
WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
WBPaper00060014:set-2(tm1630)_downregulated
WBPaper00060661:sensory-neuron_enriched
WBPaper00060683:hlh-11(ko1)_upregulated
WBPaper00060811:L1_vs_adult_upregulated_neural
WBPaper00060909:atfs-1(cmh15)_downregulated
WBPaper00061007:HB101_upregulated
WBPaper00061203:sin-3(tm1276)_upregulated
WBPaper00061203:spr-1(ok2144)_upregulated
WBPaper00061340:ALN
WBPaper00061340:AVB
WBPaper00061340:AVK
WBPaper00061340:AVL
WBPaper00061340:DA
WBPaper00061340:DB
WBPaper00061340:DD
WBPaper00061340:Intestinal_and_rectal_muscle
WBPaper00061340:RIV
WBPaper00061340:SIA
WBPaper00061340:SIB
WBPaper00061340:SMB
WBPaper00061340:SMD
WBPaper00061478:pie-1(ne4433)_upregulated
WBPaper00061478:SUMO-conjugated_protein
WBPaper00061527:hlh-30_18579-unc-43_21739
WBPaper00061527:kin-29_2839-unc-9_3883
WBPaper00061651:AVA_enriched
WBPaper00061651:AVF_enriched
WBPaper00061651:AVG_enriched
WBPaper00061651:AVJ_enriched
WBPaper00061651:AVK_enriched
WBPaper00061651:DA_enriched
WBPaper00061651:DB01_enriched
WBPaper00061651:DB_enriched
WBPaper00061651:DVA_enriched
WBPaper00061651:DVC_enriched
WBPaper00061651:FLP_enriched
WBPaper00061651:HSN_enriched
WBPaper00061651:I4_enriched
WBPaper00061651:NSM_enriched
WBPaper00061651:PDB_enriched
WBPaper00061651:PLN_enriched
WBPaper00061651:PVR_enriched
WBPaper00061651:SAB_enriched
WBPaper00061651:SIA_enriched
WBPaper00061651:SIB_enriched
WBPaper00061651:SMB_enriched
WBPaper00061651:VA_enriched
WBPaper00061651:VC_4_5_enriched
WBPaper00061651:VC_enriched
WBPaper00061651:VD_DD_enriched
WBPaper00061902:camt-1(ok515)_regulated_RMG
WBPaper00062103:neuron_enriched
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062554:MAGU-2_interacting
WBPaper00064071:NHR-49_interacting
WBPaper00064306:Agaro-oligosaccharides_upregulated
WBPaper00064315:mes-3(bn199)_upregulated_EGCs
WBPaper00064315:mes-4(bn73)_upregulated_EGCs
WBPaper00064315:mrg-1(qa6200)_upregulated_PGCs
WBPaper00064716:paraquat_downregulated
WBPaper00065096:25C_vs_20C_downregulated
WBPaper00065096:Day10_vs_Day1_downregulated
WBPaper00065373:sek-1(km4)_downregulated_cisplatin
WBPaper00065993:glp-1(e2141)_upregulated
WBPaper00066085:sin-3(tm1276)_upregulated
WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
cgc4386_cluster_5_5
cgc4489_group_8
WBPaper00025032:cluster_18
WBPaper00025141:unc-4::GFP_Enriched_Genes
WBPaper00025141:unc-4::GFP_Expressed_Genes
WBPaper00029437:dcr-1_upregulated
WBPaper00030839:Embryo_A_Class
WBPaper00030839:Embryo_Pan_Neuronal
WBPaper00030839:Larval_Pan_Neuronal
WBPaper00031003:hlh_1_enriched
WBPaper00031252:AIN-2_IP_enriched
WBPaper00031832:slr-2_regulated
WBPaper00035873:dpy-9_regulated
WBPaper00035873:dpy-10_regulated
WBPaper00037113:Chlorpyrifos_Diazinon_16C_regulated
WBPaper00037695:WC_5-day
WBPaper00040963:TA200_up
WBPaper00040963:TA300_up
WBPaper00041174:environmental
WBPaper00041174:genotypic
WBPaper00041174:genotypic_and_environmental
WBPaper00045263:isp-1(qm150)_downregulated
WBPaper00045960:L1-L4-lethargus_upregulated
WBPaper00045960:L4-lethargus_upregulated
WBPaper00048989:eat-2(ad465)_upregulated_in-DMSO
WBPaper00053236:Starvation_regulated_GR1307
[cgc5767]:expression_class_M
[cgc5767]:expression_class_SM
[cgc6390]:Cluster_C
Interaction (85)
Anatomy_functionWBbtf0223
Map_infoMapXPosition1.86244Error0.006291
Well_ordered
PositivePositive_cloneF09B9Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_data2_point3647
3648
3654
3657
3660
3662
3666
6011
7020
7022
Multi_point1339
1340
1343
1345
1348
1350
1352
1919
2010
2011
2213
2258
2275
2295
2314
2315
2316
3189
3190
3210
3274
3275
3630
3793
3819
3989
4018
4022
4023
4076
4494
Pos_neg_data3650
3665
6695
Reference (76)
MethodGene