WormBase Tree Display for Gene: WBGene00007059
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| WBGene00007059 | SMap | S_parent | Sequence | F08C6 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | vps-52 | Person_evidence | WBPerson3132 | |||||
| Sequence_name | F08C6.3 | ||||||||
| Molecular_name | F08C6.3 | ||||||||
| F08C6.3.1 | |||||||||
| CE47824 | |||||||||
| Other_name | tag-197 | Person_evidence | WBPerson201 | ||||||
| CELE_F08C6.3 | Accession_evidence | NDB | BX284606 | ||||||
| Public_name | vps-52 | ||||||||
| DB_info | Database | AceView | gene | XI185 | |||||
| WormQTL | gene | WBGene00007059 | |||||||
| WormFlux | gene | WBGene00007059 | |||||||
| NDB | locus_tag | CELE_F08C6.3 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00007059|UniProtKB=G5EFV8 | |||||||
| family | PTHR14190 | ||||||||
| NCBI | gene | 181018 | |||||||
| RefSeq | protein | NM_076881.9 | |||||||
| SwissProt | UniProtAcc | G5EFV8 | |||||||
| TREEFAM | TREEFAM_ID | TF314937 | |||||||
| UniProt_GCRP | UniProtAcc | G5EFV8 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 13:09:06 | WBPerson1845 | Event | Created | |||
| 2 | 05 Oct 2005 17:16:53 | WBPerson2970 | Event | Acquires_merge | WBGene00017242 | ||||
| Name_change | Sequence_name | F08C6.3 | |||||||
| 3 | 04 Jan 2010 16:36:04 | WBPerson2970 | Name_change | CGC_name | vps-52 | ||||
| Acquires_merge | WBGene00017242 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | vps | ||||||||
| Allele (40) | |||||||||
| Strain | WBStrain00003171 | ||||||||
| WBStrain00026563 | |||||||||
| WBStrain00035929 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (35) | |||||||||
| Ortholog (41) | |||||||||
| Structured_description | Concise_description | vps-52 encodes the C. elegans ortholog of the yeast Vps52p GARP (Golgi associated retrograde protein) complex subunit; in C. elegans, VPS-52 forms a GARP complex with VPS-51, VPS-53, and VPS-54; vps-52 is ubiquitously expressed, with particularly strong expression seen in neurons; a VPS-52::GFP fusion protein localizes to the medial Golgi and trans-Golgi network; VPS-52 physically interacts with the RAB-6.1 and RAB-6.2 Golgi-associated GTPases in vivo. | Paper_evidence | WBPaper00038455 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 13 Jan 2012 00:00:00 | ||||||||
| Automated_description | Enables small GTPase binding activity and syntaxin binding activity. Involved in negative regulation of dense core granule transport; positive regulation of dense core granule transport; and positive regulation of locomotion involved in locomotory behavior. Located in Golgi cisterna; perikaryon; and perinuclear region of cytoplasm. Part of GARP complex. Expressed in distal tip cell; neurons; somatic cell; and somatic gonad. Is an ortholog of human VPS52 (VPS52 subunit of GARP complex). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F08C6.3 | |||||||
| Corresponding_CDS_history | F08C6.3:wp223 | ||||||||
| Corresponding_transcript | F08C6.3.1 | ||||||||
| Other_sequence (13) | |||||||||
| Associated_feature | WBsf648317 | ||||||||
| WBsf662982 | |||||||||
| WBsf662983 | |||||||||
| WBsf235952 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00043979 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00012870 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00030639 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00007966 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00099100 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00076275 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern (11) | |||||||||
| Drives_construct | WBCnstr00003647 | ||||||||
| WBCnstr00013909 | |||||||||
| WBCnstr00018566 | |||||||||
| WBCnstr00022995 | |||||||||
| WBCnstr00037871 | |||||||||
| WBCnstr00038384 | |||||||||
| Construct_product | WBCnstr00018566 | ||||||||
| WBCnstr00022995 | |||||||||
| WBCnstr00037871 | |||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (95) | |||||||||
| Interaction (63) | |||||||||
| Map_info | Map | X | Position | -1.54821 | Error | 0.013575 | |||
| Positive | Positive_clone | F08C6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 5567 | |||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00038455 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00044484 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00058219 | |||||||||
| Remark | tag-197 is parsed from CGC strain VC625 | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
