WormBase Tree Display for Gene: WBGene00007117

WBGene00007117 SMap: S_parent: Sequence: B0240
  Identity: Version: 2
    Name: CGC_name: spe-42 Person_evidence: WBPerson725
      Sequence_name: B0240.2
      Molecular_name: B0240.2
        B0240.2.1
        CE39310
      Other_name: CELE_B0240.2 Accession_evidence: NDB BX284605
      Public_name: spe-42
    DB_info: Database: AceView gene 5M214
        WormQTL gene WBGene00007117
        WormFlux gene WBGene00007117
        NDB locus_tag CELE_B0240.2
        Panther gene CAEEL|WormBase=WBGene00007117|UniProtKB=Q17461
          family PTHR21041
        NCBI gene 353452
        RefSeq protein NM_182413.6
        TREEFAM TREEFAM_ID TF318655
        TrEMBL UniProtAcc Q17461
        UniProt_GCRP UniProtAcc Q17461
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:47 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 19 Sep 2005 11:52:10 WBPerson2970 Name_change: CGC_name: spe-24
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: spe
    Allele (55)
    Strain: WBStrain00034099
      WBStrain00034101
    RNASeq_FPKM (74)
    GO_annotation: 00058238
      00058239
      00058240
      00115334
    Ortholog (35)
    Paralog: WBGene00007118
      WBGene00019667 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: spe-42 encodes a novel sperm-specific seven-pass transmembrane protein with many metazoan homologs; SPE-42 has two functional domains, the DC-STAMP (dendritic cell-specific transmembrane protein) which is known to play a role in cell-cell fusion and the C4C4-type RING finger; the presumed Drosophila spe-42 orthologous gene, sneaky, is involved in sperm plasma membrane breakdown after sperm entry; spe-42 sperm exhibit normal morphology, migration and contact with oocytes but are fertilization-defective suggesting that spe-42 is required for sperm-egg interaction and thus for fertility; spe-42 is expressed only in male germ cells. Paper_evidence: WBPaper00026766
            WBPaper00036251
          Curator_confirmed: WBPerson324
          Date_last_updated: 13 Aug 2010 00:00:00
      Automated_description: Involved in single fertilization. Predicted to be located in membrane. Expressed in sperm. Is an ortholog of human DCST2 (DC-STAMP domain containing 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: B0240.2
    Corresponding_CDS_history: B0240.2:wp87
      B0240.2:wp140
      B0240.2:wp149
      B0240.2:wp151
    Corresponding_transcript: B0240.2.1
    Other_sequence: CJC05353_1
  Experimental_info: RNAi_result: WBRNAi00038786 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr3678
      Expr1028190
      Expr1142992
      Expr2016041
      Expr2034276
    Drives_construct: WBCnstr00033983
    Construct_product: WBCnstr00033983
    Microarray_results (14)
    Expression_cluster (96)
    Interaction (119)
    WBProcess: WBbiopr:00000067
  Map_info: Map: V Position: 3.32562 Error: 0.002448
    Positive: Positive_clone: B0240 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 5619
        4636
        4808
        4844
    Pseudo_map_position
  Reference (13)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene