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WormBase Tree Display for Gene: WBGene00007364

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Name Class

WBGene00007364SMapS_parentSequenceC06B3
IdentityVersion2
NameCGC_namestdh-3
Sequence_nameC06B3.5
Molecular_nameC06B3.5
C06B3.5.1
CE43017
Other_nameCELE_C06B3.5Accession_evidenceNDBBX284605
Public_namestdh-3
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:47WBPerson1971EventImportedInitial conversion from CDS class of WS125
227 Nov 2007 15:15:52WBPerson2970Name_changeCGC_namestdh-3
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classstdh
Allele (30)
RNASeq_FPKM (74)
GO_annotation00058978
00058979
00058980
00058981
00058982
Contained_in_operonCEOP5519
Ortholog (67)
Paralog (38)
Structured_descriptionConcise_descriptionstdh-3 encodes a putative steroid dehydrogenase orthologous to human HSD17B3 (OMIM:605573, mutated in pseudohermaphroditism), HSD17B12 (OMIM:609574), and HSDL1, and paralogous to LET-767, STDH-1/-2, and STDH-4; STDH-3 has no obvious function in mass RNAi assays.Paper_evidenceWBPaper00006204
Curator_confirmedWBPerson567
Date_last_updated26 Nov 2007 00:00:00
Automated_descriptionPredicted to enable oxidoreductase activity. Predicted to be involved in fatty acid elongation. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in 17-beta hydroxysteroid dehydrogenase 3 deficiency and Alzheimer's disease. Is an ortholog of human HSD17B12 (hydroxysteroid 17-beta dehydrogenase 12).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:10652Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5212)
DOID:1923Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5212)
DOID:0112248Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5212)
Molecular_infoCorresponding_CDSC06B3.5
Corresponding_CDS_historyC06B3.5:wp194
Corresponding_transcriptC06B3.5.1
Other_sequenceJI167301.1
BXC04734_1
PPC11312_1
Associated_featureWBsf232848
Experimental_infoRNAi_resultWBRNAi00039851Inferred_automaticallyRNAi_primary
WBRNAi00028553Inferred_automaticallyRNAi_primary
WBRNAi00010277Inferred_automaticallyRNAi_primary
Expr_patternExpr1010421
Expr1143933
Expr2016958
Expr2035106
Microarray_results (11)
Expression_cluster (31)
SAGE_tagSAGE:aagcaccagccttctttStrandAntisense
Interaction (59)
Map_infoMapVPosition5.75578Error0.004356
PositivePositive_cloneC06B3Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00018598
WBPaper00038491
WBPaper00042257
WBPaper00055090
WBPaper00061413
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene