WormBase Tree Display for Gene: WBGene00007698
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| WBGene00007698 | SMap | S_parent | Sequence | C24F3 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | qns-1 | Paper_evidence | WBPaper00037116 | |||||
| Sequence_name | C24F3.4 | ||||||||
| Molecular_name | C24F3.4a | ||||||||
| C24F3.4a.1 | |||||||||
| CE18521 | |||||||||
| C24F3.4b | |||||||||
| CE46056 | |||||||||
| C24F3.4c | |||||||||
| CE45996 | |||||||||
| C24F3.4b.1 | |||||||||
| C24F3.4c.1 | |||||||||
| Other_name | CELE_C24F3.4 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | qns-1 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:48 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 14 Sep 2010 16:06:52 | WBPerson2970 | Name_change | CGC_name | qns-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | qns | ||||||||
| Allele (53) | |||||||||
| Strain | WBStrain00051003 | ||||||||
| WBStrain00051228 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (22) | |||||||||
| Contained_in_operon | CEOP4364 | ||||||||
| Ortholog (51) | |||||||||
| Structured_description | Concise_description | qns-1 encodes an NAD+ synthase orthologous to human NAD synthetase 1 (HGNC:NADSYN1); by homology, QNS-1 is predicted to catalyze the final step in NAD+ synthesis; loss of qns-1 activity via RNAi results in reduced NAD+ levels and shortened adult lifespan. | Paper_evidence | WBPaper00043942 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson324 | |||||||||
| Date_last_updated | 14 Nov 2014 00:00:00 | ||||||||
| Automated_description | Enables NAD+ synthase activity. Involved in NAD biosynthetic process and determination of adult lifespan. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in high grade glioma. Is an ortholog of human NADSYN1 (NAD synthetase 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:3070 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:29832) | ||||
| EFO:MONDO:0020831 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:29832) | ||||||
| Molecular_info | Corresponding_CDS | C24F3.4a | |||||||
| C24F3.4b | |||||||||
| C24F3.4c | |||||||||
| Corresponding_transcript | C24F3.4a.1 | ||||||||
| C24F3.4b.1 | |||||||||
| C24F3.4c.1 | |||||||||
| Other_sequence (36) | |||||||||
| Associated_feature | WBsf230695 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00029149 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00069439 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00011113 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00062132 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00041094 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1017165 | ||||||||
| Expr1033329 | |||||||||
| Expr1145131 | |||||||||
| Expr2015210 | |||||||||
| Expr2033444 | |||||||||
| Microarray_results (23) | |||||||||
| Expression_cluster (84) | |||||||||
| Interaction (44) | |||||||||
| Map_info | Map | IV | Position | 4.56087 | |||||
| Positive | Positive_clone | C24F3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00036109 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00043942 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
