WormBase Tree Display for Gene: WBGene00007753
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| WBGene00007753 | SMap | S_parent | Sequence | C27A7 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | enpp-1 | Person_evidence | WBPerson44 | |||||
| WBPerson55385 | |||||||||
| Sequence_name | C27A7.1 | ||||||||
| Molecular_name (12) | |||||||||
| Other_name | CELE_C27A7.1 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | enpp-1 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:48 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 09 Dec 2021 11:50:30 | WBPerson1983 | Name_change | CGC_name | enpp-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | enpp | ||||||||
| Allele (100) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00008083 | ||||||||
| 00048966 | |||||||||
| 00048967 | |||||||||
| 00048968 | |||||||||
| 00048969 | |||||||||
| Ortholog (39) | |||||||||
| Paralog | WBGene00007755 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00008776 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00015283 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00020195 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | C27A7.1 is orthologous to the human gene NPPASE (ENPP1; OMIM:173335), which when mutated leads to disease. | Curator_confirmed | WBPerson1823 | |||||
| WBPerson567 | |||||||||
| Date_last_updated | 06 Aug 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable hydrolase activity. Predicted to be located in I band and striated muscle dense body. Expressed in ciliated neurons; pharynx; and vas deferens cuboidal cell. Human ortholog(s) of this gene implicated in several diseases, including arterial calcification of infancy; end stage renal disease; and ossification of the posterior longitudinal ligament of spine. Is an ortholog of human ENPP1 (ectonucleotide pyrophosphatase/phosphodiesterase 1); ENPP2 (ectonucleotide pyrophosphatase/phosphodiesterase 2); and ENPP3 (ectonucleotide pyrophosphatase/phosphodiesterase 3). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0050644 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3356) | ||||
| DOID:9352 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3356) | ||||||
| EFO:MONDO:0000044 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3356) | ||||||
| DOID:783 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3356) | ||||||
| DOID:3068 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3356) | ||||||
| DOID:13207 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3357) | ||||||
| DOID:0060887 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3356) | ||||||
| DOID:1287 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3356) | ||||||
| DOID:9970 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3356) | ||||||
| Molecular_info | Corresponding_CDS | C27A7.1a | |||||||
| C27A7.1b | |||||||||
| C27A7.1c | |||||||||
| C27A7.1d | |||||||||
| Corresponding_transcript | C27A7.1a.1 | ||||||||
| C27A7.1b.1 | |||||||||
| C27A7.1c.1 | |||||||||
| C27A7.1d.1 | |||||||||
| Other_sequence | EX014395.1 | ||||||||
| AI581477.1 | |||||||||
| JI245909.1 | |||||||||
| OVC00626_1 | |||||||||
| JI165437.1 | |||||||||
| CBC15576_1 | |||||||||
| HBC20340_1 | |||||||||
| Associated_feature | WBsf1001523 | ||||||||
| WBsf1020536 | |||||||||
| WBsf232608 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00029253 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00041308 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00056472 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00108542 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00011234 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00108617 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr15981 | ||||||||
| Expr15982 | |||||||||
| Expr15983 | |||||||||
| Expr1013891 | |||||||||
| Expr1033357 | |||||||||
| Expr1145350 | |||||||||
| Expr2001153 | |||||||||
| Expr2019374 | |||||||||
| Drives_construct | WBCnstr00033508 | ||||||||
| WBCnstr00042633 | |||||||||
| Construct_product | WBCnstr00033508 | ||||||||
| WBCnstr00042633 | |||||||||
| Microarray_results (26) | |||||||||
| Expression_cluster (152) | |||||||||
| Interaction (14) | |||||||||
| Map_info | Positive | Positive_clone | C27A7 | Inferred_automatically | From sequence, transcript, pseudogene data | ||||
| Interpolated_map_position | V | 3.66987 | |||||||
| Reference | WBPaper00038491 | ||||||||
| WBPaper00042257 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00062669 | |||||||||
| WBPaper00065330 | |||||||||
| Method | Gene |
