WormBase Tree Display for Gene: WBGene00008127
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| WBGene00008127 | SMap | S_parent | Sequence | C47A10 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | ddo-1 | Person_evidence | WBPerson11473 | |||||
| Sequence_name | C47A10.5 | ||||||||
| Molecular_name | C47A10.5a | ||||||||
| C47A10.5a.1 | |||||||||
| CE36691 | |||||||||
| C47A10.5b | |||||||||
| CE44074 | |||||||||
| C47A10.5b.1 | |||||||||
| Other_name | CELE_C47A10.5 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | ddo-1 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:48 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 29 Apr 2010 16:43:42 | WBPerson2970 | Name_change | CGC_name | ddo-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ddo | ||||||||
| Allele (180) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (20) | |||||||||
| Ortholog (36) | |||||||||
| Paralog | WBGene00022076 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00017648 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00017565 | Caenorhabditis elegans | From_analysis | Inparanoid_8 | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | ddo-1 encodes a D-aspartate oxidase (DASPO), paralogous to DDO-2 and DDO-3; recombinant DDO-1 has DASPO acvitity on acidic D-amino acid substrates (e.g., D-aspartate, D-glutamate, or N-methyl-D-aspartate/NMDA), with highest catalytic efficiency on D-glutamate; since the C-terminal residues of DDO-1 match the PTS1 consensus sequence, DDO-1 is predicted to be peroxisomal. | Paper_evidence | WBPaper00028859 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 25 May 2010 00:00:00 | ||||||||
| Automated_description | Enables D-aspartate oxidase activity; D-glutamate oxidase activity; and FAD binding activity. Involved in obsolete oxidation-reduction process. Predicted to be located in cytoplasm. Expressed in hypodermis and intestinal cell. Human ortholog(s) of this gene implicated in schizophrenia. Is an ortholog of human DAO (D-amino acid oxidase). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:5419 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2671) | ||||
| Molecular_info | Corresponding_CDS | C47A10.5a | |||||||
| C47A10.5b | |||||||||
| Corresponding_CDS_history | C47A10.5:wp125 | ||||||||
| Corresponding_transcript | C47A10.5a.1 | ||||||||
| C47A10.5b.1 | |||||||||
| Other_sequence (38) | |||||||||
| Associated_feature | WBsf1002742 | ||||||||
| WBsf235179 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00029887 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00042640 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00012056 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr9986 | ||||||||
| Expr1021227 | |||||||||
| Expr1146627 | |||||||||
| Expr2010828 | |||||||||
| Expr2029066 | |||||||||
| Drives_construct | WBCnstr00014990 | ||||||||
| WBCnstr00033218 | |||||||||
| Construct_product | WBCnstr00033218 | ||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (137) | |||||||||
| Interaction (15) | |||||||||
| Map_info | Map | V | Position | 13.2002 | Error | 0.000699 | |||
| Positive | Positive_clone | C47A10 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00028859 | ||||||||
| WBPaper00036387 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00040844 | |||||||||
| WBPaper00043127 | |||||||||
| WBPaper00046409 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00059638 | |||||||||
| WBPaper00065331 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
