set-6 encodes a putative histone H3 lysine-9 methyltransferase; SET-6 has no non-nematode orthologs, but several paralogs (SET-13, SET-15, SET-19, SET-20, SET-21, and SET-32); neither set-6(tm1611) nor set-6(RNAi) have any obvious phenotypes.
Enables histone H3K9 dimethyltransferase activity and histone H3K9 trimethyltransferase activity. Involved in epigenetic regulation of gene expression. Part of chromatin. Expressed in embryonic cell; gonad; muscle cell; nervous system; and sperm. Is an ortholog of human SUV39H2 (SUV39H2 histone lysine methyltransferase).
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.