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WormBase Tree Display for Gene: WBGene00008428

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Name Class

WBGene00008428SMapS_parentSequenceD2085
IdentityVersion2
NameCGC_nameeif-2BepsilonPerson_evidenceWBPerson2266
Sequence_nameD2085.3
Molecular_nameD2085.3
D2085.3.1
CE03107
Other_nameCELE_D2085.3Accession_evidenceNDBBX284602
Public_nameeif-2Bepsilon
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:49WBPerson1971EventImportedInitial conversion from CDS class of WS125
209 Jan 2017 15:00:31WBPerson2970Name_changeCGC_nameeif-2Bepsilon
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classeif
Allele (37)
RNASeq_FPKM (74)
GO_annotation00063172
00063173
00063174
00063175
00063176
00063177
00063178
Contained_in_operonCEOP2380
Ortholog (36)
ParalogWBGene00004090Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00016583Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00021628Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionD2085.3 encodes the C. elegans ortholog of the epsilon subunit of translation initiation factor eIF2B.Paper_evidenceWBPaper00032308
Curator_confirmedWBPerson1843
WBPerson1823
WBPerson567
Date_last_updated02 Dec 2010 00:00:00
Automated_descriptionPredicted to enable guanyl-nucleotide exchange factor activity; translation initiation factor activity; and translation initiation factor binding activity. Predicted to be involved in translational initiation. Predicted to be part of eukaryotic translation initiation factor 2B complex. Human ortholog(s) of this gene implicated in leukoencephalopathy with vanishing white matter 5. Is an ortholog of human EIF2B5 (eukaryotic translation initiation factor 2B subunit epsilon).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0070367Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3261)
DOID:0060868Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3261)
Molecular_infoCorresponding_CDSD2085.3
Corresponding_transcriptD2085.3.1
Other_sequence (23)
Associated_featureWBsf644495
WBsf644496
WBsf657988
WBsf221800
Experimental_infoRNAi_resultWBRNAi00008582Inferred_automaticallyRNAi_primary
WBRNAi00106684Inferred_automaticallyRNAi_primary
WBRNAi00024962Inferred_automaticallyRNAi_primary
WBRNAi00030418Inferred_automaticallyRNAi_primary
WBRNAi00043502Inferred_automaticallyRNAi_primary
WBRNAi00091062Inferred_automaticallyRNAi_primary
WBRNAi00064418Inferred_automaticallyRNAi_primary
Expr_patternExpr5630
Expr1024266
Expr1033660
Expr1147497
Expr2011246
Expr2029482
Drives_constructWBCnstr00002677
WBCnstr00032970
Construct_productWBCnstr00032970
Microarray_results (20)
Expression_cluster (108)
Interaction (98)
Map_infoMapIIPosition0.838548
PositivePositive_cloneD2085Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00027281
WBPaper00029435
WBPaper00032308
WBPaper00038491
WBPaper00055090
WBPaper00061547
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene