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WormBase Tree Display for Gene: WBGene00008591

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Name Class

WBGene00008591SMapS_parentSequenceF08H9
IdentityVersion1
NameSequence_nameF08H9.3
Molecular_nameF08H9.3
F08H9.3.1
CE09267
Other_nameCELE_F08H9.3Accession_evidenceNDBBX284605
Public_nameF08H9.3
DB_infoDatabaseAceViewgene5O942
WormQTLgeneWBGene00008591
WormFluxgeneWBGene00008591
NDBlocus_tagCELE_F08H9.3
PanthergeneCAEEL|WormBase=WBGene00008591|UniProtKB=Q19227
familyPTHR45640
NCBIgene184214
RefSeqproteinNM_074184.4
TrEMBLUniProtAccQ19227
UniProt_GCRPUniProtAccQ19227
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:49WBPerson1971EventImportedInitial conversion from CDS class of WS125
StatusLive
Gene_infoBiotypeSO:0001217
Allele (28)
RNASeq_FPKM (74)
GO_annotation00063980
00063981
00063982
00063983
00063984
Ortholog (55)
Paralog (17)
Structured_descriptionConcise_descriptionF08H9.3 encodes a heat shock protein (HSP) of the HSP16 class; unlike most HSP16s in C. elegans, it is specifically expressed in a particular tissue (the larval pharynx and the anterior adult pharynx), and its expression is not strongly induced by heat shock; however, F08H9.3 expression is increased by heat shock (with adult expression in the full pharynx) and probably aids heat shock resistance, since F08H9.3(RNAi) animals have sensitivity to heat shock that is sporadically higher than normal; in general, HSP16 proteins are thought to act as passive ligands for unfolded proteins that keep them safe from aggregation until the proteins can be refolded by a large (ATP-consuming) HSP.Paper_evidenceWBPaper00005740
WBPaper00013029
WBPaper00013239
WBPaper00013280
WBPaper00013579
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable unfolded protein binding activity. Predicted to be involved in protein refolding and response to heat. Predicted to be located in cytoplasm and nucleus. Expressed in intestinal cell and pharynx.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF08H9.3
Corresponding_transcriptF08H9.3.1
Associated_featureWBsf979021
WBsf234954
Experimental_infoRNAi_result (13)
Expr_patternExpr2457
Expr15511
Expr1010802
Expr1148027
Expr2002314
Expr2020533
Drives_constructWBCnstr00010845
WBCnstr00032848
WBCnstr00042202
Construct_productWBCnstr00032848
WBCnstr00042202
Microarray_results (17)
Expression_cluster (175)
Interaction (60)
Map_infoPositivePositive_cloneF08H9Inferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionV6.4131
ReferenceWBPaper00005740
WBPaper00013029
WBPaper00028419
WBPaper00031124
WBPaper00038491
WBPaper00044578
WBPaper00055090
WBPaper00060685
MethodGene