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WormBase Tree Display for Gene: WBGene00008592

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Name Class

WBGene00008592SMapS_parentSequenceF08H9
IdentityVersion1
NameSequence_nameF08H9.4
Molecular_nameF08H9.4a
F08H9.4a.1
CE09268
F08H9.4b
CE48344
F08H9.4b.1
Other_nameCELE_F08H9.4Accession_evidenceNDBBX284605
Public_nameF08H9.4
DB_infoDatabaseAceViewgene5O946
WormQTLgeneWBGene00008592
WormFluxgeneWBGene00008592
NDBlocus_tagCELE_F08H9.4
PanthergeneCAEEL|WormBase=WBGene00008592|UniProtKB=Q19228
familyPTHR45640
NCBIgene184215
RefSeqproteinNM_001307766.1
NM_074185.5
TrEMBLUniProtAccN1NV13
Q19228
UniProt_GCRPUniProtAccQ19228
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:49WBPerson1971EventImportedInitial conversion from CDS class of WS125
StatusLive
Gene_infoBiotypeSO:0001217
Allele (33)
StrainWBStrain00032299
RNASeq_FPKM (74)
GO_annotation00024384
00024385
00024386
00024387
00024388
00063985
Ortholog (54)
Paralog (17)
Structured_descriptionConcise_descriptionF08H9.4 encodes a heat shock protein (HSP) of the HSP16 class; unlike most HSP16s in C. elegans, it is specifically expressed in a particular tissue (the excretory canal and ventral nerve-cord neurons), and its expression is only mildly induced by heat shock; however, F08H9.4 expression is increased by heat shock, is induced in a new tissue type (intestine) by heat shock, and probably aids heat shock resistance, since F08H9.4(RNAi) animals die as embryos in heat shock at a higher rate than normal; in general, HSP16 proteins are thought to act as passive ligands for unfolded proteins that keep them safe from aggregation until the proteins can be refolded by a large (ATP-consuming) HSP.Paper_evidenceWBPaper00004424
WBPaper00005740
WBPaper00013029
WBPaper00013239
WBPaper00013280
WBPaper00013579
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable unfolded protein binding activity. Involved in response to topologically incorrect protein. Predicted to be located in cytoplasm and nucleus. Expressed in excretory canal; head neurons; and ventral cord neurons.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF08H9.4a
F08H9.4b
Corresponding_transcriptF08H9.4a.1
F08H9.4b.1
Associated_featureWBsf234955
Experimental_infoRNAi_result (11)
Expr_patternExpr2458
Expr15520
Expr1027128
Expr1148028
Expr2002315
Expr2020534
Drives_constructWBCnstr00010846
WBCnstr00032847
WBCnstr00042211
Construct_productWBCnstr00032847
WBCnstr00042211
Microarray_results (18)
Expression_cluster (138)
Interaction (54)
Map_infoPositivePositive_cloneF08H9Inferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionV6.41359
ReferenceWBPaper00005740
WBPaper00013029
WBPaper00028419
WBPaper00031124
WBPaper00034765
WBPaper00038491
WBPaper00055090
WBPaper00060685
WBPaper00061938
WBPaper00065158
MethodGene