WormBase Tree Display for Gene: WBGene00008999
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| WBGene00008999 | SMap | S_parent | Sequence | CHROMOSOME_X | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | myrf-2 | Person_evidence | WBPerson7150 | |||||
| Sequence_name | F21A10.2 | ||||||||
| Molecular_name (21) | |||||||||
| Other_name | CELE_F21A10.2 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | myrf-2 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:49 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 09 Dec 2014 15:51:18 | WBPerson2970 | Name_change | CGC_name | myrf-2 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | myrf | ||||||||
| Allele (227) | |||||||||
| Strain | WBStrain00036617 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (26) | |||||||||
| Ortholog (51) | |||||||||
| Paralog | WBGene00004134 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | myrf-2 encodes a protein with a glutamine/asparagine-rich domain, homologous to human MYRF (myelin regulatory factor); MYRF-2 contains a well-conserved paralog in the C. elegans genome, MYRF-1, encoded by F59B10.1. | Paper_evidence | WBPaper00040293 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 19 Dec 2014 00:00:00 | ||||||||
| Automated_description | Predicted to enable DNA-binding transcription factor activity and sequence-specific DNA binding activity. Predicted to be involved in positive regulation of DNA-templated transcription and protein autoprocessing. Predicted to be located in endoplasmic reticulum membrane and nucleus. Human ortholog(s) of this gene implicated in cerebral infarction; congenital diaphragmatic hernia; and eye disease (multiple). Is an ortholog of human MYRF (myelin regulatory factor) and MYRFL (myelin regulatory factor like). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0080634 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1181) | ||||
| DOID:3827 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1181) | ||||||
| DOID:9834 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1181) | ||||||
| DOID:1405 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1181) | ||||||
| DOID:3526 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1181) | ||||||
| Molecular_info | Corresponding_CDS | F21A10.2a | |||||||
| F21A10.2b | |||||||||
| F21A10.2c | |||||||||
| F21A10.2d | |||||||||
| F21A10.2e | |||||||||
| Corresponding_CDS_history | F21A10.2:wp83 | ||||||||
| Corresponding_transcript (11) | |||||||||
| Other_sequence (20) | |||||||||
| Associated_feature (21) | |||||||||
| Transcription_factor | WBTranscriptionFactor000671 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00013650 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00045155 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00031194 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00013649 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00045156 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr10306 | ||||||||
| Expr10307 | |||||||||
| Expr13355 | |||||||||
| Expr13356 | |||||||||
| Expr15840 | |||||||||
| Expr1017279 | |||||||||
| Expr1033918 | |||||||||
| Expr1149095 | |||||||||
| Expr2013847 | |||||||||
| Expr2032087 | |||||||||
| Drives_construct | WBCnstr00015242 | ||||||||
| WBCnstr00015243 | |||||||||
| WBCnstr00032536 | |||||||||
| Construct_product | WBCnstr00032536 | ||||||||
| WBCnstr00038841 | |||||||||
| Regulate_expr_cluster | WBPaper00061377:MYRF-2_interacting | ||||||||
| Microarray_results (43) | |||||||||
| Expression_cluster (150) | |||||||||
| Interaction (308) | |||||||||
| Anatomy_function | WBbtf1098 | ||||||||
| Map_info | Map | X | Position | 1.87196 | |||||
| Positive | Positive_clone | F21A10 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00038491 | ||||||||
| WBPaper00040293 | |||||||||
| WBPaper00051143 | |||||||||
| WBPaper00052297 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00058394 | |||||||||
| WBPaper00062590 | |||||||||
| WBPaper00065331 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
