WormBase Tree Display for Gene: WBGene00009178

WBGene00009178 SMap: S_parent: Sequence: CHROMOSOME_I
  Identity: Version: 2
    Name: CGC_name: uggt-2 Paper_evidence: WBPaper00040397
          Person_evidence: WBPerson12962
      Sequence_name: F26H9.8
      Molecular_name: F26H9.8
        F26H9.8.1
        CE42103
      Other_name: CELE_F26H9.8 Accession_evidence: NDB BX284601
      Public_name: uggt-2
    DB_info: Database: AceView gene 1J903
        WormQTL gene WBGene00009178
        WormFlux gene WBGene00009178
        NDB locus_tag CELE_F26H9.8
        Panther gene CAEEL|WormBase=WBGene00009178|UniProtKB=G5EF14
          family PTHR11226
        NCBI gene 172758
        RefSeq protein NM_060083.5
        TREEFAM TREEFAM_ID TF300320
        TrEMBL UniProtAcc G5EF14
        UniProt_GCRP UniProtAcc G5EF14
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:49 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 11 Nov 2011 16:17:07 WBPerson2970 Name_change: CGC_name: uggt-2
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: uggt
    Allele (96)
    Strain: WBStrain00036995
    RNASeq_FPKM (74)
    GO_annotation (19)
    Ortholog (56)
    Paralog: WBGene00018604 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
    Structured_description: Concise_description: uggt-2 encodes one of two C. elegans homologs of UDP-Glc:glycoprotein glucosyltransferase (UGGT), an endoplasmic reticulum enzyme involved in quality control of glycoprotein folding; loss of uggt-2 activity via RNAi indicates that uggt-2 is an essential embryonic gene that is also required for regulating the rate of larval developmental; uggt-2 interacts genetically with ire-1 with respect to basal unfolded protein response during larval development; uggt-2 is expressed throughout larval development, with peak levels seen at the L2/L3 stages. Paper_evidence: WBPaper00040397
          Curator_confirmed: WBPerson1843
          Date_last_updated: 14 Nov 2011 00:00:00
      Automated_description: Predicted to enable UDP-glucose:glycoprotein glucosyltransferase activity and unfolded protein binding activity. Involved in IRE1-mediated unfolded protein response; regulation of embryonic development; and regulation of nematode larval development. Predicted to be located in endoplasmic reticulum. Is an ortholog of human UGGT1 (UDP-glucose glycoprotein glucosyltransferase 1) and UGGT2 (UDP-glucose glycoprotein glucosyltransferase 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F26H9.8
    Corresponding_CDS_history: F26H9.8:wp187
    Corresponding_transcript: F26H9.8.1
    Other_sequence: MAC00138_2
      Name_isotig04816
      MA00557
      MIC03277_1
    Associated_feature: WBsf656708
      WBsf218269
  Experimental_info: RNAi_result (14)
    Expr_pattern: Expr9682
      Expr1010326
      Expr1149623
      Expr2017753
      Expr2035892
    Drives_construct: WBCnstr00032396
    Construct_product: WBCnstr00032396
    Microarray_results (19)
    Expression_cluster (137)
    Interaction (20)
  Map_info: Map: I Position: 3.74311
    Positive: Positive_clone: F26H9 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00029024
    WBPaper00038491
    WBPaper00039794
    WBPaper00040397
    WBPaper00042697
    WBPaper00055090
    WBPaper00060116
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene