WormBase Tree Display for Gene: WBGene00009594
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| WBGene00009594 | SMap | S_parent | Sequence | F40F12 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | cyld-1 | |||||||
| Sequence_name | F40F12.5 | ||||||||
| Molecular_name | F40F12.5a | ||||||||
| F40F12.5a.1 | |||||||||
| CE36647 | |||||||||
| F40F12.5b | |||||||||
| CE46609 | |||||||||
| F40F12.5c | |||||||||
| CE46674 | |||||||||
| F40F12.5b.1 | |||||||||
| F40F12.5c.1 | |||||||||
| Other_name | CELE_F40F12.5 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | cyld-1 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:50 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 07 Jan 2008 15:11:50 | WBPerson2970 | Name_change | CGC_name | cyld-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cyld | ||||||||
| Allele (245) | |||||||||
| Strain | WBStrain00033285 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00023340 | ||||||||
| 00023341 | |||||||||
| 00023342 | |||||||||
| 00023343 | |||||||||
| 00023344 | |||||||||
| 00023345 | |||||||||
| 00023346 | |||||||||
| 00023347 | |||||||||
| 00117236 | |||||||||
| 00117237 | |||||||||
| Ortholog (43) | |||||||||
| Paralog | WBGene00004470 | Caenorhabditis elegans | From_analysis | Panther | |||||
| Structured_description | Concise_description | F40F12.5 encodes an ortholog of human CYLD1 (OMIM:605018, mutated incylindromatosis); CYLD1 binds several members of the NF-kappaBsignalling pathway, and can deubiquitinate target proteins. | Paper_evidence | WBPaper00028837 | |||||
| Curator_confirmed | WBPerson1823 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 11 Dec 2006 00:00:00 | ||||||||
| Automated_description | Predicted to enable K63-linked deubiquitinase activity and cysteine-type deubiquitinase activity. Predicted to be located in cytosol. Expressed in several structures, including arcade cell; pharyngeal cell; pharyngeal-intestinal valve; rectal gland cell; and spermatheca. Human ortholog(s) of this gene implicated in Brooke-Spiegler syndrome. Is an ortholog of human CYLD (CYLD lysine 63 deubiquitinase). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | EFO:MONDO:0017161 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2584) | ||||
| DOID:0050693 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2584) | ||||||
| Molecular_info | Corresponding_CDS | F40F12.5a | |||||||
| F40F12.5b | |||||||||
| F40F12.5c | |||||||||
| Corresponding_CDS_history | F40F12.5:wp124 | ||||||||
| F40F12.5a:wp119 | |||||||||
| F40F12.5b:wp119 | |||||||||
| Corresponding_transcript | F40F12.5a.1 | ||||||||
| F40F12.5b.1 | |||||||||
| F40F12.5c.1 | |||||||||
| Other_sequence (41) | |||||||||
| Associated_feature (16) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00094870 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00046860 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00014654 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00046861 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00114323 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00006406 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00032028 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00112453 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00014653 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00006396 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr11304 | ||||||||
| Expr1027638 | |||||||||
| Expr1034199 | |||||||||
| Expr1150727 | |||||||||
| Expr2010661 | |||||||||
| Expr2028901 | |||||||||
| Drives_construct | WBCnstr00032074 | ||||||||
| Construct_product | WBCnstr00032074 | ||||||||
| Microarray_results (29) | |||||||||
| Expression_cluster (145) | |||||||||
| Interaction (45) | |||||||||
| Map_info | Map | III | Position | 1.1561 | Error | 0.00606 | |||
| Positive | Positive_clone | F40F12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00038491 | ||||||||
| WBPaper00041771 | |||||||||
| WBPaper00050049 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00061750 | |||||||||
| WBPaper00063875 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
