WormBase Tree Display for Gene: WBGene00010685
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| WBGene00010685 | SMap | S_parent | Sequence | K08F9 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | aipl-1 | Person_evidence | WBPerson463 | |||||
| Sequence_name | K08F9.2 | ||||||||
| Molecular_name | K08F9.2 | ||||||||
| K08F9.2.1 | |||||||||
| CE11944 | |||||||||
| Other_name | tag-216 | Person_evidence | WBPerson201 | ||||||
| CELE_K08F9.2 | Accession_evidence | NDB | BX284605 | ||||||
| Public_name | aipl-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:51 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 23 Dec 2004 08:51:14 | WBPerson2970 | Name_change | CGC_name | tag-216 | ||||
| 3 | 16 Feb 2009 11:49:54 | WBPerson2970 | Name_change | CGC_name | aipl-1 | ||||
| Other_name | tag-216 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | aipl | ||||||||
| Allele (43) | |||||||||
| Strain | WBStrain00035992 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00031100 | ||||||||
| 00031101 | |||||||||
| 00031102 | |||||||||
| 00031103 | |||||||||
| 00031104 | |||||||||
| 00031105 | |||||||||
| 00031106 | |||||||||
| Ortholog (44) | |||||||||
| Paralog | WBGene00006810 | Caenorhabditis elegans | From_analysis | Inparanoid_8 | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | aipl-1 encodes a conserved WD-repeat protein that cooperates with ADF/cofilin and is highly homologous to AIP-1; the sequence of the encoded protein is 66% identical to UNC-78; aipl-1 and unc-78 have redundant and overlapping functions in organized assembly of actin filaments in embryonic muscle and the unc-78 and aipl-1 double mutant is embryonic lethal; both AIPL-1 isoforms preferentially cooperate with UNC-60B, a muscle-specific ADF/cofilin for actin filament disassembly in embryonic muscle; AIPL-1 affects localization of only F-actin-bound UNC-60B; AIPL-1 is expressed in the embryonic neurons, the intestine and the body wall muscle, in adult spermatheca and body wall muscles; AIPL-1 majorly functions in early embryonic muscle and can compensate for the function of UNC-78 in the body wall muscle. | Paper_evidence | WBPaper00038403 | |||||
| Curator_confirmed | WBPerson12884 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 14 Jun 2011 00:00:00 | ||||||||
| Automated_description | Predicted to enable actin filament binding activity. Involved in actin filament organization and regulation of protein localization. Predicted to be located in cortical actin cytoskeleton. Expressed in body wall musculature; head neurons; intestine; and spermatheca. Is an ortholog of human WDR1 (WD repeat domain 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | K08F9.2 | |||||||
| Corresponding_transcript | K08F9.2.1 | ||||||||
| Other_sequence (28) | |||||||||
| Associated_feature | WBsf669770 | ||||||||
| WBsf977371 | |||||||||
| WBsf977372 | |||||||||
| WBsf1002246 | |||||||||
| WBsf235034 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00008100 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00034159 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00050334 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00086429 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00086428 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00016840 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr9298 | ||||||||
| Expr1024053 | |||||||||
| Expr1034675 | |||||||||
| Expr1154037 | |||||||||
| Expr2009275 | |||||||||
| Expr2027512 | |||||||||
| Drives_construct | WBCnstr00013882 | ||||||||
| WBCnstr00037851 | |||||||||
| Construct_product | WBCnstr00037851 | ||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (155) | |||||||||
| Interaction (111) | |||||||||
| Map_info | Map | V | Position | 7.46301 | Error | 0.004489 | |||
| Positive | Positive_clone | K08F9 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4917 | |||||||
| 5379 | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00028381 | ||||||||
| WBPaper00038403 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00040301 | |||||||||
| WBPaper00049094 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00061290 | |||||||||
| WBPaper00066112 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
