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WormBase Tree Display for Gene: WBGene00010732

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Name Class

WBGene00010732SMapS_parentSequenceK10C3
IdentityVersion1
NameSequence_nameK10C3.5
Molecular_nameK10C3.5a
K10C3.5a.1
CE32469
K10C3.5b
CE38396
K10C3.5b.1
Other_nameCELE_K10C3.5Accession_evidenceNDBBX284601
Public_nameK10C3.5
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:51WBPerson1971EventImportedInitial conversion from CDS class of WS125
StatusLive
Gene_infoBiotypeSO:0001217
Allele (80)
RNASeq_FPKM (74)
GO_annotation00031107
00031108
00031109
00031110
00031111
00031112
00118075
00118076
Contained_in_operonCEOP1566
Ortholog (35)
Paralog (17)
Structured_descriptionConcise_descriptionK10C3.5 encodes, by alternative splicing, two isoforms of an ortholog of budding yeast Ria1p/Efl1p and human EFTUD1; by orthology with Ria1p, K10C3.5 is predicted to act in concert with W06E11.4 to recycle EIF-6 during during maturation of 60S ribosomal subunits; however, K10C3.5 has no obvious phenotype in mass RNAi assays.Paper_evidenceWBPaper00032020
Curator_confirmedWBPerson567
Date_last_updated24 Jul 2008 00:00:00
Automated_descriptionPredicted to enable GTPase activity and ribosome binding activity. Predicted to be involved in cytosolic ribosome assembly. Predicted to be located in cytosol. Predicted to be part of ribonucleoprotein complex. Human ortholog(s) of this gene implicated in Shwachman-Diamond syndrome. Is an ortholog of human EFL1 (elongation factor like GTPase 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0060479Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:25789)
Molecular_infoCorresponding_CDSK10C3.5a
K10C3.5b
Corresponding_CDS_historyK10C3.5:wp90
Corresponding_transcriptK10C3.5a.1
K10C3.5b.1
Other_sequence (52)
Associated_featureWBsf656803
WBsf656804
WBsf656805
WBsf716669
WBsf218362
Experimental_infoRNAi_resultWBRNAi00034244Inferred_automaticallyRNAi_primary
WBRNAi00050501Inferred_automaticallyRNAi_primary
WBRNAi00062531Inferred_automaticallyRNAi_primary
Expr_patternExpr1019428
Expr1034699
Expr1154212
Expr2005019
Expr2023238
Drives_constructWBCnstr00031187
Construct_productWBCnstr00031187
Microarray_results (23)
Expression_cluster (104)
Interaction (133)
Map_infoPositivePositive_cloneK10C3Inferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionI3.95948
ReferenceWBPaper00038491
WBPaper00055090
MethodGene