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WormBase Tree Display for Gene: WBGene00011502

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Name Class

WBGene00011502SMapS_parentSequenceT05G5
IdentityVersion2
NameCGC_namevps-53Person_evidenceWBPerson3132
Sequence_nameT05G5.8
Molecular_nameT05G5.8a
T05G5.8a.1
CE47826
T05G5.8b
CE47898
T05G5.8b.1
Other_nameCELE_T05G5.8Accession_evidenceNDBBX284603
Public_namevps-53
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:52WBPerson1971EventImportedInitial conversion from CDS class of WS125
204 Jan 2010 16:36:04WBPerson2970Name_changeCGC_namevps-53
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classvps
Allele (53)
StrainWBStrain00037162
RNASeq_FPKM (74)
GO_annotation (32)
Contained_in_operonCEOP3616
Ortholog (40)
Structured_descriptionConcise_descriptionvps-53 encodes the C. elegans ortholog of the yeast Vps53p GARP (Golgi associated retrograde protein) complex subunit; in C. elegans, VPS-53 forms a GARP complex with VPS-51, VPS-52, and VPS-54; vps-53 is ubiquitously expressed, with particularly strong expression seen in neurons.Paper_evidenceWBPaper00038455
Curator_confirmedWBPerson1843
Date_last_updated13 Jan 2012 00:00:00
Automated_descriptionInvolved in positive regulation of locomotion involved in locomotory behavior; regulation of brood size; and regulation of dense core granule transport. Located in perikaryon and perinuclear region of cytoplasm. Part of GARP complex. Expressed in body wall musculature; intestine; and pharynx. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 2E. Is an ortholog of human VPS53 (VPS53 subunit of GARP complex).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0060271Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:25608)
Molecular_infoCorresponding_CDST05G5.8a
T05G5.8b
Corresponding_CDS_historyT05G5.8:wp179
Corresponding_transcriptT05G5.8a.1
T05G5.8b.1
Other_sequence (45)
Associated_featureWBsf667324
WBsf667325
WBsf667326
WBsf227363
WBsf227364
Experimental_infoRNAi_resultWBRNAi00006073Inferred_automaticallyRNAi_primary
WBRNAi00035231Inferred_automaticallyRNAi_primary
WBRNAi00002405Inferred_automaticallyRNAi_primary
WBRNAi00099101Inferred_automaticallyRNAi_primary
WBRNAi00052570Inferred_automaticallyRNAi_primary
Expr_patternExpr9334
Expr9335
Expr12991
Expr1017059
Expr1035065
Expr1156186
Expr2018036
Expr2036173
Drives_constructWBCnstr00013910
WBCnstr00022994
WBCnstr00030606
WBCnstr00038383
Construct_productWBCnstr00022994
WBCnstr00030606
Microarray_results (21)
Expression_cluster (87)
Interaction (41)
Map_infoMapIIIPosition0.982702Error0.003167
PositivePositive_cloneT05G5Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00038455
WBPaper00038491
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene