WormBase Tree Display for Gene: WBGene00012497

WBGene00012497 SMap: S_parent: Sequence: CHROMOSOME_IV
  Identity: Version: 2
    Name: CGC_name: ragc-1 Person_evidence: WBPerson187
      Sequence_name: Y24F12A.2
      Molecular_name: Y24F12A.2a
        Y24F12A.2a.1
        CE24193
        Y24F12A.2b
        CE49755
        Y24F12A.2b.1
      Other_name: CELE_Y24F12A.2 Accession_evidence: NDB BX284604
      Public_name: ragc-1
    DB_info: Database: AceView gene 4M368
        WormQTL gene WBGene00012497
        WormFlux gene WBGene00012497
        NDB locus_tag CELE_Y24F12A.2
        Panther gene CAEEL|WormBase=WBGene00012497|UniProtKB=G5EGB3
          family PTHR11259
        NCBI gene 178084
        RefSeq protein NM_001306958.3
            NM_069786.6
        TrEMBL UniProtAcc G5EGB3
            A0A061ACG4
        UniProt_GCRP UniProtAcc G5EGB3
        OMIM gene 608268
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:53 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 20 May 2009 11:51:30 WBPerson9133 Name_change: CGC_name: ragc-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: ragc
    Allele (24)
    Strain: WBStrain00001910
    RNASeq_FPKM (74)
    GO_annotation (13)
    Ortholog (42)
    Paralog: WBGene00006414 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Automated_description: Predicted to enable GTPase activity. Involved in determination of adult lifespan and regulation of autophagosome assembly. Predicted to be located in lysosome and nucleus. Predicted to be part of Gtr1-Gtr2 GTPase complex. Human ortholog(s) of this gene implicated in primary hypomagnesemia. Is an ortholog of human RRAGC (Ras related GTP binding C) and RRAGD (Ras related GTP binding D). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0060879 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:19903)
  Molecular_info: Corresponding_CDS: Y24F12A.2a
      Y24F12A.2b
    Corresponding_transcript: Y24F12A.2a.1
      Y24F12A.2b.1
    Other_sequence (53)
    Associated_feature: WBsf652232
      WBsf997890
      WBsf230897
      WBsf230898
  Experimental_info: RNAi_result: WBRNAi00055725 Inferred_automatically: RNAi_primary
      WBRNAi00026631 Inferred_automatically: RNAi_primary
      WBRNAi00020132 Inferred_automatically: RNAi_primary
      WBRNAi00036734 Inferred_automatically: RNAi_primary
      WBRNAi00027510 Inferred_automatically: RNAi_primary
      WBRNAi00062504 Inferred_automatically: RNAi_primary
      WBRNAi00090957 Inferred_automatically: RNAi_primary
      WBRNAi00055726 Inferred_automatically: RNAi_primary
      WBRNAi00026630 Inferred_automatically: RNAi_primary
    Expr_pattern: Chronogram918
      Expr6910
      Expr1015898
      Expr1035537
      Expr1159247
      Expr2015246
      Expr2033480
    Drives_construct: WBCnstr00002699
      WBCnstr00029942
    Construct_product: WBCnstr00029942
    Microarray_results (18)
    Expression_cluster (99)
    Interaction (33)
  Map_info: Map: IV Position: 5.04207 Error: 0.006672
    Positive: Positive_clone: Y24F12A Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00043089
    WBPaper00055090
    WBPaper00056742
    WBPaper00056804
    WBPaper00059297
    WBPaper00061156
    WBPaper00061779
    WBPaper00062518
    WBPaper00064006
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene