WormBase Tree Display for Gene: WBGene00012815
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| WBGene00012815 | SMap | S_parent | Sequence | Y43F8B | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | phy-4 | Paper_evidence | WBPaper00031524 | |||||
| Person_evidence | WBPerson466 | ||||||||
| Sequence_name | Y43F8B.4 | ||||||||
| Molecular_name | Y43F8B.4a | ||||||||
| Y43F8B.4a.1 | |||||||||
| CE23349 | |||||||||
| Y43F8B.4b | |||||||||
| CE42496 | |||||||||
| Y43F8B.4b.1 | |||||||||
| Other_name | CELE_Y43F8B.4 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | phy-4 | ||||||||
| DB_info | Database | AceView | gene | 5T982 | |||||
| WormQTL | gene | WBGene00012815 | |||||||
| WormFlux | gene | WBGene00012815 | |||||||
| NDB | locus_tag | CELE_Y43F8B.4 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00012815|UniProtKB=B1V8J4 | |||||||
| family | PTHR10869 | ||||||||
| NCBI | gene | 189869 | |||||||
| RefSeq | protein | NM_001129576.4 | |||||||
| NM_001129577.3 | |||||||||
| TrEMBL | UniProtAcc | B1V8J3 | |||||||
| B1V8J4 | |||||||||
| UniProt_GCRP | UniProtAcc | B1V8J4 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:54 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 27 Feb 2008 14:43:32 | WBPerson2970 | Name_change | CGC_name | phy-4 | ||||
| 3 | 03 Apr 2008 15:13:06 | WBPerson4025 | Event | Split_into | WBGene00077688 | ||||
| Split_into | WBGene00077688 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | phy | ||||||||
| Allele (97) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00005750 | ||||||||
| 00005751 | |||||||||
| 00005752 | |||||||||
| 00005753 | |||||||||
| 00005754 | |||||||||
| 00005755 | |||||||||
| 00005756 | |||||||||
| 00119822 | |||||||||
| 00119823 | |||||||||
| 00119824 | |||||||||
| Ortholog (19) | |||||||||
| Paralog | WBGene00001077 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| WormBase-Compara | |||||||||
| WBGene00004026 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| WormBase-Compara | |||||||||
| WBGene00015773 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| WormBase-Compara | |||||||||
| WBGene00004025 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00077688 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | phy-4.1 encodes a polypeptide that show sequence similarity to the C-terminal regions of the catalytic subunits of the human and C. elegans C-P4Hs (human alpha (I), (II), and (III) (OMIM: 176710, 600608, 608987,) and C. elegans PHY-1, PHY-2, and PHY-3); phy-4.1 RNAi does not lead to any obvious phenotypic abnormalities; tetramers and dimers containing PHY-4.1 has a distinct substrate specificity from the other C-P4Hs in that they hydroxylate poly(L-proline) and certain other proline-rich peptides, including ones that are expressed in the pharynx, in addition to collagen-like peptides; PHY-4.1 hydroxylates additional proline-rich proteins in vivo; spatial expression of phy-4.1 is restricted to the pharyngeal gland cells, the lumen of the pharynx and excretory duct. | Paper_evidence | WBPaper00031524 | |||||
| Curator_confirmed | WBPerson12884 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 18 Aug 2011 00:00:00 | ||||||||
| Automated_description | Contributes to peptidyl-proline 4-dioxygenase activity. Part of procollagen-proline 4-dioxygenase complex. Expressed in excretory duct; pharyngeal gland cell; and pharyngeal-intestinal valve. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | Y43F8B.4a | |||||||
| Y43F8B.4b | |||||||||
| Corresponding_CDS_history | Y43F8B.4:wp189 | ||||||||
| Corresponding_transcript | Y43F8B.4a.1 | ||||||||
| Y43F8B.4b.1 | |||||||||
| Associated_feature | WBsf653575 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00078036 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00078038 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00020556 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00078037 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00019953 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr7998 | ||||||||
| Expr7999 | |||||||||
| Expr1011679 | |||||||||
| Expr1159987 | |||||||||
| Expr2014916 | |||||||||
| Expr2033151 | |||||||||
| Drives_construct | WBCnstr00013052 | ||||||||
| WBCnstr00029830 | |||||||||
| Construct_product | WBCnstr00029830 | ||||||||
| Antibody | WBAntibody00001376 | ||||||||
| Microarray_results (11) | |||||||||
| Expression_cluster (42) | |||||||||
| Interaction (26) | |||||||||
| Map_info | Map | V | Position | 22.1793 | Error | 0.068414 | |||
| Positive | Positive_clone | Y43F8B | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00031524 | ||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
