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WormBase Tree Display for Gene: WBGene00013300

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Name Class

WBGene00013300SMapS_parentSequenceY57G11C
IdentityVersion2
NameCGC_namelgc-7Paper_evidenceWBPaper00029376
Person_evidenceWBPerson1430
Sequence_nameY57G11C.2
Molecular_nameY57G11C.2
Y57G11C.2.1
CE36675
Other_nameCELE_Y57G11C.2Accession_evidenceNDBBX284604
Public_namelgc-7
DB_infoDatabaseAceViewgene4P481
WormQTLgeneWBGene00013300
WormFluxgeneWBGene00013300
NDBlocus_tagCELE_Y57G11C.2
PanthergeneCAEEL|WormBase=WBGene00013300|UniProtKB=O18228
familyPTHR18945
NCBIgene190370
RefSeqproteinNM_070376.3
TREEFAMTREEFAM_IDTF319821
TrEMBLUniProtAccO18228
UniProt_GCRPUniProtAccO18228
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:54WBPerson1971EventImportedInitial conversion from CDS class of WS125
218 May 2007 16:58:23WBPerson2970Name_changeCGC_namelgc-7
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classlgc
Allele (95)
StrainWBStrain00050961
RNASeq_FPKM (74)
GO_annotation (17)
Ortholog (31)
Paralog (100)
Structured_descriptionAutomated_descriptionPredicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. Human ortholog(s) of this gene implicated in irritable bowel syndrome. Is an ortholog of human HTR3A (5-hydroxytryptamine receptor 3A) and HTR3E (5-hydroxytryptamine receptor 3E).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:9778Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5297)
Molecular_infoCorresponding_CDSY57G11C.2
Corresponding_CDS_historyY57G11C.2:wp124
Corresponding_transcriptY57G11C.2.1
Experimental_infoRNAi_resultWBRNAi00066358Inferred_automaticallyRNAi_primary
WBRNAi00057691Inferred_automaticallyRNAi_primary
WBRNAi00037599Inferred_automaticallyRNAi_primary
WBRNAi00021140Inferred_automaticallyRNAi_primary
Expr_patternExpr1022704
Expr1161103
Expr2013138
Expr2031370
Microarray_results (17)
Expression_cluster (26)
Interaction (62)
Map_infoMapIVPosition12.3871Error0.005186
PositivePositive_cloneY57G11CInferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00038491
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene