WormBase Tree Display for Gene: WBGene00013338

WBGene00013338 SMap: S_parent: Sequence: Y57G11C
  Identity: Version: 2
    Name: CGC_name: lgc-8 Paper_evidence: WBPaper00029376
          Person_evidence: WBPerson1430
      Sequence_name: Y57G11C.49
      Molecular_name: Y57G11C.49
        Y57G11C.49.1
        CE41069
      Other_name: CELE_Y57G11C.49 Accession_evidence: NDB BX284604
      Public_name: lgc-8
    DB_info: Database: AceView gene 4P483
        WormQTL gene WBGene00013338
        WormFlux gene WBGene00013338
        NDB locus_tag CELE_Y57G11C.49
        Panther gene CAEEL|WormBase=WBGene00013338|UniProtKB=Q6BEQ0
          family PTHR18945
        NCBI gene 3564870
        RefSeq protein NM_001028362.2
        TREEFAM TREEFAM_ID TF319821
        TrEMBL UniProtAcc Q6BEQ0
        UniProt_GCRP UniProtAcc Q6BEQ0
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:54 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 18 May 2007 16:58:23 WBPerson2970 Name_change: CGC_name: lgc-8
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: lgc
    Allele (77)
    Strain: WBStrain00050963
    RNASeq_FPKM (74)
    GO_annotation (15)
    Ortholog (30)
    Paralog (100)
    Structured_description: Automated_description: Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. Human ortholog(s) of this gene implicated in irritable bowel syndrome. Is an ortholog of human HTR3A (5-hydroxytryptamine receptor 3A) and HTR3E (5-hydroxytryptamine receptor 3E). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:9778 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:5297)
  Molecular_info: Corresponding_CDS: Y57G11C.49
    Corresponding_CDS_history: Y57G11C.49:wp175
    Corresponding_transcript: Y57G11C.49.1
    Associated_feature: WBsf655063
      WBsf998620
  Experimental_info: RNAi_result: WBRNAi00066358 Inferred_automatically: RNAi_primary
      WBRNAi00021140 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1161129
      Expr2013139
      Expr2031371
    Drives_construct: WBCnstr00029676
    Construct_product: WBCnstr00029676
    Microarray_results: 172886_x_at
      A_12_P119645
      Aff_Y57G11C.2
      GPL21109_Y57G11C.146
      GPL21109_Y57G11C.916
      GPL8304_CE_WBGene00013338_A
      GPL8673_Y57G11C_49P00114
      GPL8673_Y57G11C_49P00429
    Expression_cluster (22)
  Map_info: Map: IV Position: 12.3973 Error: 0.004205
    Positive: Positive_clone: Y57G11C Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene