WormBase Tree Display for Gene: WBGene00014095
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| WBGene00014095 | SMap | S_parent | Sequence | ZK829 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | gdh-1 | Paper_evidence | WBPaper21864529 | |||||
| Sequence_name | ZK829.4 | ||||||||
| Molecular_name | ZK829.4 | ||||||||
| ZK829.4.1 | |||||||||
| CE06652 | |||||||||
| ZK829.4.2 | |||||||||
| Other_name | CELE_ZK829.4 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | gdh-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:55 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 31 Aug 2011 09:11:34 | WBPerson2970 | Name_change | CGC_name | gdh-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | gdh | ||||||||
| Allele (37) | |||||||||
| Strain | WBStrain00001547 | ||||||||
| WBStrain00002442 | |||||||||
| WBStrain00055460 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00079104 | ||||||||
| 00079105 | |||||||||
| 00079106 | |||||||||
| 00079107 | |||||||||
| 00079108 | |||||||||
| 00079109 | |||||||||
| 00120823 | |||||||||
| 00120824 | |||||||||
| 00120825 | |||||||||
| Ortholog (46) | |||||||||
| Paralog | WBGene00045131 | Caenorhabditis elegans | From_analysis | modENCODE_Pseudogenes | |||||
| Structured_description | Concise_description | gdh-1 encodes a glutamate dehydrogenase, required in mass RNAi assays for normal fertility and rapid growth, that is expressed in larval and adult pharynx, intestine, and rectal gland cells; GDH-1 is orthologous to human GLUD1 (OMIM:138130, mutated in hyperinsulinemic hypoglycemia and hyperammonemia) and GLUD2 (OMIM:300144). | Paper_evidence | WBPaper00006525 | |||||
| WBPaper00024497 | |||||||||
| WBPaper00029258 | |||||||||
| WBPaper00031006 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson1823 | |||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 20 Sep 2011 00:00:00 | ||||||||
| Automated_description | Predicted to enable glutamate dehydrogenase (NAD+) activity. Predicted to be involved in glutamate catabolic process. Predicted to be located in mitochondrion. Expressed in head; intestine; pharynx; rectal gland cell; and tail. Human ortholog(s) of this gene implicated in Alzheimer's disease; glucose metabolism disease (multiple); and late onset Parkinson's disease. Is an ortholog of human GLUD1 (glutamate dehydrogenase 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:10652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4335) | ||||
| DOID:9993 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4335) | ||||||
| DOID:0070217 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4335) | ||||||
| DOID:2018 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4335) | ||||||
| Molecular_info | Corresponding_CDS | ZK829.4 | |||||||
| Corresponding_transcript | ZK829.4.1 | ||||||||
| ZK829.4.2 | |||||||||
| Other_sequence (403) | |||||||||
| Associated_feature (13) | |||||||||
| Experimental_info | RNAi_result (17) | ||||||||
| Expr_pattern | Chronogram204 | ||||||||
| Expr7259 | |||||||||
| Expr7260 | |||||||||
| Expr14639 | |||||||||
| Expr1013000 | |||||||||
| Expr1036313 | |||||||||
| Expr1163175 | |||||||||
| Expr2012006 | |||||||||
| Expr2030242 | |||||||||
| Drives_construct | WBCnstr00002389 | ||||||||
| WBCnstr00029313 | |||||||||
| WBCnstr00041190 | |||||||||
| Construct_product | WBCnstr00016475 | ||||||||
| WBCnstr00029313 | |||||||||
| WBCnstr00041190 | |||||||||
| Microarray_results (26) | |||||||||
| Expression_cluster (222) | |||||||||
| Interaction (153) | |||||||||
| Map_info | Map | IV | Position | 5.45243 | Error | 0.000619 | |||
| Positive | Positive_clone | ZK829 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00033090 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00041022 | |||||||||
| WBPaper00042178 | |||||||||
| WBPaper00049595 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00059575 | |||||||||
| WBPaper00061178 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
