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WormBase Tree Display for Gene: WBGene00015413

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Name Class

WBGene00015413SMapS_parentSequenceC04C3
IdentityVersion2
NameCGC_namepdhb-1Person_evidenceWBPerson1983
WBPerson261
Sequence_nameC04C3.3
Molecular_nameC04C3.3
C04C3.3.1
CE27647
Other_nameCELE_C04C3.3Accession_evidenceNDBBX284604
Public_namepdhb-1
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:56WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
208 Dec 2011 12:14:43WBPerson2970Name_changeCGC_namepdhb-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classpdhb
Allele (73)
StrainWBStrain00003083
WBStrain00002809
RNASeq_FPKM (74)
GO_annotation (13)
Ortholog (38)
ParalogWBGene00006518Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00008506Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionC04C3.3 encodes the C. elegans ortholog of the pyruvate dehydrogenase complex E1 beta subunit (PDHB); by homology to mammalian enzymes, the product of C04C3.3 is predicted to function in mitochondria to catalyze the irreversible decarboxylation of pyruvate to acetyl-CoA.Curator_confirmedWBPerson1843
Date_last_updated11 Nov 2008 00:00:00
Automated_descriptionPredicted to enable pyruvate dehydrogenase (acetyl-transferring) activity. Predicted to be involved in acetyl-CoA biosynthetic process from pyruvate. Located in mitochondrion. Expressed in several structures, including head. Human ortholog(s) of this gene implicated in pyruvate decarboxylase deficiency. Is an ortholog of human PDHB (pyruvate dehydrogenase E1 subunit beta).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:3649Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:8808)
Molecular_infoCorresponding_CDSC04C3.3
Corresponding_transcriptC04C3.3.1
Other_sequence (143)
Associated_featureWBsf228097
Experimental_infoRNAi_result (14)
Expr_patternChronogram1211
Chronogram1881
Expr5139
Expr5140
Expr16127
Expr1022308
Expr1036596
Expr1143687
Expr2014803
Expr2033037
Drives_constructWBCnstr00003336
WBCnstr00004583
Microarray_results (22)
Expression_cluster (157)
Interaction (130)
Map_infoMapIVPosition-4.52326
PositivePositive_cloneC04C3Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00027145
WBPaper00028360
WBPaper00031648
WBPaper00038491
WBPaper00049828
WBPaper00055090
WBPaper00056909
WBPaper00060084
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene