WormBase Tree Display for Gene: WBGene00015413
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WBGene00015413 | SMap | S_parent | Sequence | C04C3 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | pdhb-1 | Person_evidence | WBPerson1983 | |||||
WBPerson261 | |||||||||
Sequence_name | C04C3.3 | ||||||||
Molecular_name | C04C3.3 | ||||||||
C04C3.3.1 | |||||||||
CE27647 | |||||||||
Other_name | CELE_C04C3.3 | Accession_evidence | NDB | BX284604 | |||||
Public_name | pdhb-1 | ||||||||
DB_info | Database (13) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 28 May 2004 13:30:56 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
2 | 08 Dec 2011 12:14:43 | WBPerson2970 | Name_change | CGC_name | pdhb-1 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | pdhb | ||||||||
Allele (73) | |||||||||
Strain | WBStrain00003083 | ||||||||
WBStrain00002809 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (13) | |||||||||
Ortholog (38) | |||||||||
Paralog | WBGene00006518 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
WBGene00008506 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
Structured_description | Concise_description | C04C3.3 encodes the C. elegans ortholog of the pyruvate dehydrogenase complex E1 beta subunit (PDHB); by homology to mammalian enzymes, the product of C04C3.3 is predicted to function in mitochondria to catalyze the irreversible decarboxylation of pyruvate to acetyl-CoA. | Curator_confirmed | WBPerson1843 | |||||
Date_last_updated | 11 Nov 2008 00:00:00 | ||||||||
Automated_description | Predicted to enable pyruvate dehydrogenase (acetyl-transferring) activity. Predicted to be involved in acetyl-CoA biosynthetic process from pyruvate. Located in mitochondrion. Expressed in several structures, including head. Human ortholog(s) of this gene implicated in pyruvate decarboxylase deficiency. Is an ortholog of human PDHB (pyruvate dehydrogenase E1 subunit beta). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:3649 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:8808) | ||||
Molecular_info | Corresponding_CDS | C04C3.3 | |||||||
Corresponding_transcript | C04C3.3.1 | ||||||||
Other_sequence (143) | |||||||||
Associated_feature | WBsf228097 | ||||||||
Experimental_info | RNAi_result (14) | ||||||||
Expr_pattern | Chronogram1211 | ||||||||
Chronogram1881 | |||||||||
Expr5139 | |||||||||
Expr5140 | |||||||||
Expr16127 | |||||||||
Expr1022308 | |||||||||
Expr1036596 | |||||||||
Expr1143687 | |||||||||
Expr2014803 | |||||||||
Expr2033037 | |||||||||
Drives_construct | WBCnstr00003336 | ||||||||
WBCnstr00004583 | |||||||||
Microarray_results (22) | |||||||||
Expression_cluster (157) | |||||||||
Interaction (130) | |||||||||
Map_info | Map | IV | Position | -4.52326 | |||||
Positive | Positive_clone | C04C3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference | WBPaper00027145 | ||||||||
WBPaper00028360 | |||||||||
WBPaper00031648 | |||||||||
WBPaper00038491 | |||||||||
WBPaper00049828 | |||||||||
WBPaper00055090 | |||||||||
WBPaper00056909 | |||||||||
WBPaper00060084 | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |