WormBase Tree Display for Gene: WBGene00015628

WBGene00015628 SMap: S_parent: Sequence: C09B9
  Identity: Version: 3
    Name: CGC_name: best-6 Person_evidence: WBPerson260
      Sequence_name: C09B9.3
      Molecular_name: C09B9.3
        C09B9.3.1
        CE44268
        C09B9.3.2
      Other_name: CELE_C09B9.3 Accession_evidence: NDB BX284604
      Public_name: best-6
    DB_info: Database: AceView gene 4F786
        WormQTL gene WBGene00015628
        WormFlux gene WBGene00015628
        NDB locus_tag CELE_C09B9.3
        Panther gene CAEEL|WormBase=WBGene00015628|UniProtKB=Q17851
          family PTHR10736
        NCBI gene 177270
        RefSeq protein NM_001268339.2
        SwissProt UniProtAcc Q17851
        UniProt_GCRP UniProtAcc Q17851
        OMIM gene 607854
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:56 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 07 Feb 2012 16:30:56 WBPerson2970 Name_change: CGC_name: best-6
        3 17 Aug 2012 09:56:12 WBPerson1849 Event: Split_into: WBGene00220250
      Split_into: WBGene00220250
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: best
    Allele (39)
    Strain: WBStrain00051363
    RNASeq_FPKM (74)
    GO_annotation: 00059433
      00059434
      00059435
      00059436
      00059437
      00059438
      00059439
      00059440
      00121451
    Ortholog (35)
    Paralog (26)
    Structured_description: Automated_description: Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in autosomal dominant vitreoretinochoroidopathy and retinal degeneration (multiple). Is an ortholog of several human genes including BEST1 (bestrophin 1); BEST2 (bestrophin 2); and BEST3 (bestrophin 3). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0110396 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12703)
      DOID:4448 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12703)
      DOID:0050661 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12703)
      DOID:0050662 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12703)
      DOID:0111569 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12703)
  Molecular_info: Corresponding_CDS: C09B9.3
    Corresponding_CDS_history: C09B9.3a:wp233
    Corresponding_transcript: C09B9.3.1
      C09B9.3.2
    Associated_feature: WBsf667923
      WBsf667924
      WBsf996413
      WBsf1017322
      WBsf230039
  Experimental_info: RNAi_result: WBRNAi00010512 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1010534
      Expr1144242
    Drives_construct: WBCnstr00028704
    Construct_product: WBCnstr00028704
    Microarray_results: GPL19516_CGZ0003660
      GPL19516_CGZ0003661
      GPL21109_C09B9.3.1
    Expression_cluster (65)
    Interaction (19)
  Map_info: Map: IV Position: 1.41994
    Positive: Positive_clone: C09B9 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene