WormBase Tree Display for Gene: WBGene00015697
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| WBGene00015697 | SMap | S_parent | Sequence | C10H11 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | mlst-8 | Person_evidence | WBPerson555 | |||||
| Sequence_name | C10H11.8 | ||||||||
| Molecular_name | C10H11.8a | ||||||||
| C10H11.8a.1 | |||||||||
| CE08097 | |||||||||
| C10H11.8b | |||||||||
| CE45568 | |||||||||
| C10H11.8b.1 | |||||||||
| Other_name | CeLST8 | Paper_evidence | WBPaper00040247 | ||||||
| lst-8 | Paper_evidence | WBPaper00044096 | |||||||
| CELE_C10H11.8 | Accession_evidence | NDB | BX284601 | ||||||
| Public_name | mlst-8 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:30:56 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 29 Nov 2016 11:06:21 | WBPerson2970 | Name_change | CGC_name | mlst-8 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | mlst | ||||||||
| Allele (41) | |||||||||
| Strain | WBStrain00036244 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (20) | |||||||||
| Contained_in_operon | CEOP1780 | ||||||||
| Ortholog (33) | |||||||||
| Structured_description | Concise_description | mlst-8 encodes a WD40 repeat-containing protein that is the C. elegans ortholog of Saccharomyces cerevisiae and mammalian Lst8; by homology, MLST-8 is predicted to function as a member of the TOR complexes to regulate growth, development, and actin cytoskeleton organization; loss of mlst-8 activity via RNAi results in increased fat content, developmental delays, and small body size; RNAi targeting mlst-8 as well as let-502 results in defects in P cell migration. | Paper_evidence | WBPaper00026774 | |||||
| WBPaper00032966 | |||||||||
| WBPaper00037861 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 10 Jan 2018 00:00:00 | ||||||||
| Automated_description | Involved in mesendoderm development. Predicted to be located in cytoplasm. Predicted to be part of TORC1 complex and TORC2 complex. Is an ortholog of human MLST8 (MTOR associated protein, LST8 homolog). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C10H11.8a | |||||||
| C10H11.8b | |||||||||
| Corresponding_transcript | C10H11.8a.1 | ||||||||
| C10H11.8b.1 | |||||||||
| Other_sequence | CGC00608_1 | ||||||||
| CJC13785_1 | |||||||||
| CR01353 | |||||||||
| CBC08244_1 | |||||||||
| CRC06258_1 | |||||||||
| Associated_feature | WBsf219316 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00040338 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00024533 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00105992 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00002943 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00106042 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00024534 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00078070 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00107053 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00002939 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00116436 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1017778 | ||||||||
| Expr1036719 | |||||||||
| Expr1144407 | |||||||||
| Expr2013603 | |||||||||
| Expr2031836 | |||||||||
| Drives_construct | WBCnstr00028643 | ||||||||
| Construct_product | WBCnstr00028643 | ||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (70) | |||||||||
| Interaction (30) | |||||||||
| Map_info | Map | I | Position | -0.763211 | |||||
| Positive | Positive_clone | C10H11 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00032966 | ||||||||
| WBPaper00037861 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00040247 | |||||||||
| WBPaper00044096 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00064064 | |||||||||
| WBPaper00064339 | |||||||||
| WBPaper00066161 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
