WormBase Tree Display for Gene: WBGene00016912

WBGene00016912 SMap: S_parent: Sequence: C54D1
  Identity: Version: 2
    Name (5)
    DB_info: Database: AceView gene XH759
        WormQTL gene WBGene00016912
        WormFlux gene WBGene00016912
        NDB locus_tag CELE_C54D1.2
        Panther gene CAEEL|WormBase=WBGene00016912|UniProtKB=Q18821
          family PTHR22802
        NCBI gene 183775
        RefSeq protein NM_076801.2
        TREEFAM TREEFAM_ID TF317914
        TrEMBL UniProtAcc Q18821
        UniProt_GCRP UniProtAcc Q18821
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:58 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 28 Sep 2005 17:40:12 WBPerson2970 Name_change: CGC_name: clec-86
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: clec
    Allele (12)
    RNASeq_FPKM (74)
    GO_annotation: 00062464
      00062465
      00062466
    Ortholog (24)
    Paralog (25)
    Structured_description: Automated_description: Predicted to enable carbohydrate binding activity. Involved in innate immune response. Predicted to be located in external side of plasma membrane. Human ortholog(s) of this gene implicated in Alzheimer's disease; autoimmune disease (multiple); and cholangiocarcinoma. Is an ortholog of human REG1A (regenerating family member 1 alpha); REG1B (regenerating family member 1 beta); and REG3G (regenerating family member 3 gamma). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:10652 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:9951)
      DOID:9744 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:9951)
      DOID:4947 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:9951)
      DOID:12894 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:9951)
  Molecular_info: Corresponding_CDS: C54D1.2
    Corresponding_transcript: C54D1.2.1
    Other_sequence: CBC03154_1
    Associated_feature: WBsf648279
      WBsf235901
  Experimental_info: RNAi_result: WBRNAi00078252 Inferred_automatically: RNAi_primary
      WBRNAi00030134 Inferred_automatically: RNAi_primary
      WBRNAi00012376 Inferred_automatically: RNAi_primary
      WBRNAi00043127 Inferred_automatically: RNAi_primary
      WBRNAi00089019 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1010355
      Expr1037257
      Expr1147096
      Expr2010217
      Expr2028458
    Drives_construct: WBCnstr00027710
    Construct_product: WBCnstr00027710
    Microarray_results (19)
    Expression_cluster: WBPaper00032425:up_in_zfp-1
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00033070:Rhine_upregulated
      WBPaper00034636:heat_shock_upregulated
      WBPaper00037624:ets-4(ok165)_downregulated
      WBPaper00037950:intestine_larva_enriched
      WBPaper00038168:lin-15B(n744)_upregulated
      WBPaper00038237:age-1_upregulated_intestine_rescue
      WBPaper00038237:age-1_upregulated_neuron_rescue
      WBPaper00038237:age-1_upregulated_nontransgenic
      WBPaper00038438:Harposporium_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
      WBPaper00041071:spe-44_downregulated
      WBPaper00042194:nhr-114(RNAi)_upregulated
      WBPaper00042215:wdr-23(tm1817)_upregulated
      WBPaper00042561:smg-2(RNAi)_upregulated
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00044316:CH3HgCl_2.0uM_downregulated
      WBPaper00044316:CH3HgCl_7.5uM_downregulated
      WBPaper00044736:oscillating_dev_expression
      WBPaper00044760:somatic_specific
      WBPaper00045017:blmp-1(tm548)_downregulated
      WBPaper00045390:tunicamycin_upregulated
      WBPaper00045401:N.parisii_30h_upregulated
      WBPaper00045401:N.parisii_40h_upregulated
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045571:germline-ablation_upregulated
      WBPaper00045774:clk-1_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00047132:glp-1(ts)-25C_upregulated
      WBPaper00048971:daf-16(mgDf50)_upregulated_L1
      WBPaper00049018:swsn-2.2(RNAi)_upregulated
      WBPaper00049484:elt-2(RNAi)_downregulated_L4
      WBPaper00049545:cco-1(RNAi)_downregulated
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049736:15deg-then-25deg(12hr)_upregulated_N2
      WBPaper00049736:daf-2(e1370)_downregulated_15deg-then-25deg(12hr)
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00050096:P.aeruginosa_upregulated
      WBPaper00050121:mir-60(n4947)_upregulated
      WBPaper00050182:lmn-1(L535P)_upregulated
      WBPaper00050370:dpy-21(e428)_L3_downregulated
      WBPaper00050412:cco-1(RNAi)_downregulated_lin-65(n3441)
      WBPaper00050412:cco-1(RNAi)_downregulated_met-2(ok2307)
      WBPaper00050412:cco-1(RNAi)_downregulated_N2
      WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
      WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_adult_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050990:intestine_enriched
      WBPaper00050990:intestine_expressed
      WBPaper00051039:intestine_enriched
      WBPaper00051404:alg-1(gk214)_upregulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053295:lin-22(icb38)_downregulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053388:dauer_regulated_Cluster3
      WBPaper00053402:cco-1(RNAi)_downregulated
      WBPaper00053402:his-3(RNAi)_downregulated
      WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_downregulated
      WBPaper00053606:N2_vs_elt-2(ca15)_downregulated
      WBPaper00053664:ins-11(tm1053)_upregulated
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00053810:isp-1(qm150)_downregulated
      WBPaper00054758:alg-1(gk204)_downregulated
      WBPaper00055354:Rapamycin-Psora-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Psora_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055386:eat-2(ad465)_upregulated
      WBPaper00055482:pmt-2(RNAi)_downregulated
      WBPaper00055941:nuo-6(qm200);atfs-1(gk3094)_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00055981:fog-2(q71)_downregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056034:pals-25(jy9)_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056167:ifo-1(kc2)_downregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056446:hsb-1(cg116)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056471:flcn-1(ok975)_upregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056586:kri-1(ok1251)_upregulated
      WBPaper00056826:hmc_biased
      WBPaper00057068:ints-4(RNAi)_downregulated
      WBPaper00057149:prgn-1(tm985)_upregulated
      WBPaper00057154:HeatShock_downregulated_miRNA-target
      WBPaper00057154:HeatShock_upregulated_mRNA
      WBPaper00057158:mdt-15(tm2182)_dependent_15C_downregulated
      WBPaper00057347:nhr-14(tm1473)_upreglated
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058711:paraquat_downregulated
      WBPaper00058711:skn-1(lax188)_upregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00058969:RIS_depleted
      WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
      WBPaper00059426:SiO2-nanoparticles_downregulated
      WBPaper00059567:olrn-1(ums9)_regulated
      WBPaper00059604:fluvastatin_upregulated_dlk-1(km12)
      WBPaper00059604:fluvastatin_upregulated_N2
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059728:5ug_cholesterol_upregulated
      WBPaper00059728:20ug_cholesterol_upregulated
      WBPaper00060014:set-2(zr2012)_upregulated
      WBPaper00060084:cco-1(RNAi)_downregulated_N2
      WBPaper00060273:isp-1(qm150)_downregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060399:pqm-1(ok485)_downregulated_CoCl2_6hr
      WBPaper00060445:ikb-1(nr2027)_downregulated_L1
      WBPaper00060459:bcat-1(RNAi)_upregulated
      WBPaper00060526:plp-1(ok2155)_downregulated
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060683:hlh-11(overexpression)_upregulated
      WBPaper00060909:atfs-1(et18)_downregulated
      WBPaper00061319:pnp-1(jy90)_upregulated
      WBPaper00061319:pnp-1(jy121)_upregulated
      WBPaper00061340:ASE_parent
      WBPaper00061340:F_U
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061527:Y41D4B.17-K10D11.6
      WBPaper00061572:oleic-acid-specific_mating_upregulated
      WBPaper00061952:daf-18(nr2037)_upregulated
      WBPaper00061952:daf-18(yh1)_upregulated
      WBPaper00062056:dpl-1(n2994)_upregulated
      WBPaper00062118:neural-HSF-1_downregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062347:blmp-1(tm548)_downregulated
      WBPaper00062446:nhr-8(hd117)_downregulated
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064107:lin-35(n745)_downregulated
      WBPaper00064130:Beta-Amyloid_24h_upregulated_mRNA
      WBPaper00064156:lipl-4(overexpress)_upregulated
      WBPaper00064403:Heat-killed-E.Coli_upregulated
      WBPaper00064473:ets-4(rrr16)_upregulated
      WBPaper00064494:postdauer_downregulated_AWA
      WBPaper00064532:pals-22(jy3)_downregulated
      WBPaper00064532:pals-25(icb98)_upregulated
      WBPaper00064539:nhr-114(gk849)_downregulated
      WBPaper00064602:egl-9(sa307)_downregulated
      WBPaper00064632:daf-2(e1370)_downregulated_intestine
      WBPaper00064716:paraquat_downregulated
      WBPaper00064727:daf-2(e1370)_downregulated
      WBPaper00064769:him-17(me24)_upregulated
      WBPaper00064871:PA14_upregulated_AWA
      WBPaper00065005:sams-3(RNAi)_upregulated
      WBPaper00065005:sams-4(RNAi)_upregulated
      WBPaper00065029:cadmium_upregulated
      WBPaper00065074:glna(-)_downregulated
      WBPaper00065086:N2_N.parisii_regulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065096:npr-8(ok1439)_downregulated_Day10_20C
      WBPaper00065158:25C_vs_15C_upregulated_AFD
      WBPaper00065392:Lb.plantarum_upregulated
      WBPaper00065578:gcn-1(nc40)_downregulated
      WBPaper00065734:unc-25(e156)_upregulated
      WBPaper00065749:endu-2(tm4977)_upregulated
      WBPaper00065749:Heat-Shock_upregulated_N2
      WBPaper00065841:35_1
      WBPaper00065841:35_3
      WBPaper00065841:85_0
      WBPaper00065841:138_0
      WBPaper00065975:P-body_vs_oocyte_depleted
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00065995:M.humicola-extract_upregulated_N2
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      WBPaper00066232:ash-2(RNAi)_upregulated_WT
      WBPaper00066232:hsf-1(RNAi)_upregulated_ash-2
      WBPaper00066232:hsf-1(RNAi)_upregulated_WT
      cgc4489_group_8
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00027722:Microbacterium_nematophilum_upregulated
      WBPaper00028482:PA14_upregulated
      WBPaper00028789:PA14_vs_gacA_upregulated_8hr
      WBPaper00028789:PA14_vs_OP50_upregulated_4hr
      WBPaper00028789:PA14_vs_OP50_upregulated_8hr
      WBPaper00029437:rde-1_downregulated
      WBPaper00029437:rde-4_downregulated
      WBPaper00031832:slr-2_regulated
      WBPaper00033101:spr-5_regulated
      WBPaper00035588:alg-1(-)_upregulated
      WBPaper00035873:osm-11_regulated
      WBPaper00036286:Pattern_D
      WBPaper00037113:CPF_16C_down-regulated
      WBPaper00037113:CPF_DZN_16C_down-regulated
      WBPaper00037113:Diazinon_16C_regulated
      WBPaper00037113:DZN_16C_down-regulated
      WBPaper00038172:crh-1null_down_regulated
      WBPaper00038172:tax-6null_down_regulated
      WBPaper00038231:Cry5B_1.5-fold_downregulated
      WBPaper00038231:Cry5B_2-fold_downregulated
      WBPaper00038462:aging_downregulated
      WBPaper00039851:HK_C_albicans_vs_HK_OP50
      WBPaper00040210:Chlorpyrifos_16C_regulated
      WBPaper00040210:Chlorpyrifos_24C_regulated
      WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated
      WBPaper00040210:Diazinon_24C_regulated
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.5
      WBPaper00040821:Au-NP_regulated
      WBPaper00040823:alg-1(gk214)_upregulated
      WBPaper00040858:eQTL_age_regulated_aging
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040858:eQTL_regulated_aging
      WBPaper00040858:eQTL_regulated_developing
      WBPaper00040858:eQTL_regulated_reproductive
      WBPaper00040963:Q100_down
      WBPaper00040963:Q200_down
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041002:HF_11d_2.0mM_Up
      WBPaper00041002:HQ_3d_2.0mM_Up
      WBPaper00041609:hpl-1_hpl-2_upregulated
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_24h
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_51h
      WBPaper00042258:DA1877_upregulated_GravidAdult
      WBPaper00045401:N.parisii_34h_upregulated_N2
      WBPaper00045673:colistin_upregulated
      WBPaper00046083:oga-1(ok1207)_OP50_downregulated
      WBPaper00047070:DAF-16-dependent_UV_response
      WBPaper00047070:N2_starvation_downregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
      WBPaper00050515:nipi-3(fr4)_downregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      [cgc6390]:Cluster_B
    Interaction: WBInteraction000031645
      WBInteraction000234585
  Map_info: Map: X Position: -1.82766
    Positive: Positive_clone: C54D1 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00027722
    WBPaper00031686
    WBPaper00033987
    WBPaper00037524
    WBPaper00038491
    WBPaper00055090
    WBPaper00065681
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene