WormBase Tree Display for Gene: WBGene00016935
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| WBGene00016935 | SMap | S_parent | Sequence | C54G7 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | ifta-1 | Paper_evidence | WBPaper00028563 | |||||
| Sequence_name | C54G7.4 | ||||||||
| Molecular_name | C54G7.4 | ||||||||
| C54G7.4.1 | |||||||||
| CE49989 | |||||||||
| Other_name | ift-121 | ||||||||
| CELE_C54G7.4 | Accession_evidence | NDB | BX284606 | ||||||
| Public_name | ifta-1 | ||||||||
| DB_info | Database | AceView | gene | XG166 | |||||
| WormQTL | gene | WBGene00016935 | |||||||
| WormFlux | gene | WBGene00016935 | |||||||
| NDB | locus_tag | CELE_C54G7.4 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00016935|UniProtKB=Q18859 | |||||||
| family | PTHR16517 | ||||||||
| NCBI | gene | 183817 | |||||||
| RefSeq | protein | NM_076539.7 | |||||||
| TrEMBL | UniProtAcc | Q18859 | |||||||
| UniProt_GCRP | UniProtAcc | Q18859 | |||||||
| OMIM | gene | 613602 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:30:58 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 01 Nov 2006 11:33:19 | WBPerson1847 | Name_change | CGC_name | ifta-1 | ||||
| 3 | 11 Jun 2018 11:44:56 | WBPerson1983 | Name_change | Other_name | ift-121 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ifta | ||||||||
| Allele (101) | |||||||||
| Strain | WBStrain00002636 | ||||||||
| WBStrain00027645 | |||||||||
| WBStrain00037122 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (11) | |||||||||
| Ortholog (47) | |||||||||
| Paralog | WBGene00006655 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00022139 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | ifta-1 encodes a evolutionarily conserved protein found in ciliated unicellular and multicellular organisms including humans and is absent in non-ciliated organisms like yeast; IFTA-1 contains a X-box and several N-terminal WD repeats; ifta-1 is required for retrograde intraflagellar transport and likely associates with, or is a core component of the IFT-A subcomplex; ifta-1 is also required for the proper functioning and assembly of cilia; IFTA-1 localizes to the basal body of the cilium. | Paper_evidence | WBPaper00028563 | |||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 28 Oct 2008 00:00:00 | ||||||||
| Automated_description | Involved in chemotaxis; intraciliary transport; and non-motile cilium assembly. Located in axoneme and ciliary basal body. Expressed in amphid neurons; inner labial neurons; outer labial neurons; and phasmid neurons. Human ortholog(s) of this gene implicated in Ellis-Van Creveld syndrome; cranioectodermal dysplasia 2; and short-rib thoracic dysplasia 7 with or without polydactyly. Is an ortholog of human WDR35 (WD repeat domain 35). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0110090 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:29250) | ||||
| DOID:12714 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:29250) | ||||||
| DOID:0080804 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:29250) | ||||||
| Molecular_info | Corresponding_CDS | C54G7.4 | |||||||
| Corresponding_CDS_history | C54G7.4:wp133 | ||||||||
| C54G7.4:wp244 | |||||||||
| Corresponding_transcript | C54G7.4.1 | ||||||||
| Other_sequence | JI223993.1 | ||||||||
| Associated_feature | WBsf047481 | ||||||||
| WBsf653991 | |||||||||
| WBsf670535 | |||||||||
| WBsf670536 | |||||||||
| WBsf237386 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00012416 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00043192 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr3728 | ||||||||
| Expr5589 | |||||||||
| Expr8277 | |||||||||
| Expr1019755 | |||||||||
| Expr1037265 | |||||||||
| Expr1147170 | |||||||||
| Expr2012700 | |||||||||
| Expr2030936 | |||||||||
| Drives_construct | WBCnstr00003183 | ||||||||
| WBCnstr00011632 | |||||||||
| WBCnstr00013233 | |||||||||
| WBCnstr00027695 | |||||||||
| Construct_product | WBCnstr00013233 | ||||||||
| WBCnstr00027695 | |||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (183) | |||||||||
| Interaction (12) | |||||||||
| Map_info | Map | X | Position | -4.84199 | Error | 0.066321 | |||
| Positive | Positive_clone | C54G7 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00013451 | ||||||||
| WBPaper00026601 | |||||||||
| WBPaper00028563 | |||||||||
| WBPaper00029016 | |||||||||
| WBPaper00031170 | |||||||||
| WBPaper00036268 | |||||||||
| WBPaper00037724 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00065994 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
