WormBase Tree Display for Gene: WBGene00017683
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| WBGene00017683 | SMap | S_parent | Sequence | F21H12 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | rbbp-5 | Paper_evidence | WBPaper00035979 | |||||
| WBPaper00038409 | |||||||||
| Person_evidence | WBPerson2615 | ||||||||
| Sequence_name | F21H12.1 | ||||||||
| Molecular_name | F21H12.1 | ||||||||
| F21H12.1.1 | |||||||||
| CE32634 | |||||||||
| Other_name | lsy-15 | Person_evidence | WBPerson260 | ||||||
| CELE_F21H12.1 | Accession_evidence | NDB | BX284602 | ||||||
| Public_name | rbbp-5 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:30:59 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 28 Aug 2012 11:44:41 | WBPerson2970 | Name_change | CGC_name | rbbp-5 | ||||
| 3 | 05 Dec 2012 09:19:09 | WBPerson2970 | Event | Acquires_merge | WBGene00045426 | ||||
| Name_change | Other_name | lsy-15 | |||||||
| Acquires_merge | WBGene00045426 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | rbbp | ||||||||
| Allele (27) | |||||||||
| Strain | WBStrain00029529 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (13) | |||||||||
| Ortholog (34) | |||||||||
| Paralog | WBGene00016582 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
| Structured_description | Concise_description | rbbp-5 encodes a WD40 repeat-containing protein that is the C. elegans homolog of Saccharomyces cerevisiae Swd1 and mammalian RbBP5 (Retinoblastoma binding protein 5), members of Set1/MLL methyltransferase complexes; in C. elegans, rbbp-5 activity is required for histone H3 lysine 4 methylation, specifically H3K4me3 and H3K4me2, during early embryonic development and in adult germline stem cells; accordingly, rbbp-5 is required for embryonic development, germline stem cell maintenance and development, and reproduction; rbbp-5 is also required for normal body morphology and egg-laying behavior. | Paper_evidence | WBPaper00006395 | |||||
| WBPaper00036429 | |||||||||
| WBPaper00038279 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 30 Aug 2012 00:00:00 | ||||||||
| Automated_description | Involved in several processes, including heterochromatin organization; multicellular organism reproduction; and transdifferentiation. Part of MLL3/4 complex. Is an ortholog of human RBBP5 (RB binding protein 5, histone lysine methyltransferase complex subunit). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F21H12.1 | |||||||
| Corresponding_CDS_history | F21H12.1:wp88 | ||||||||
| Corresponding_transcript | F21H12.1.1 | ||||||||
| Other_sequence (33) | |||||||||
| Associated_feature | WBsf644254 | ||||||||
| WBsf657655 | |||||||||
| WBsf221390 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00065294 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00025167 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00082605 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00087822 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00045245 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00082443 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00087846 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00008677 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00087828 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00089505 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1022453 | ||||||||
| Expr1037588 | |||||||||
| Expr1149174 | |||||||||
| Expr2015263 | |||||||||
| Expr2033497 | |||||||||
| Drives_construct | WBCnstr00027105 | ||||||||
| Construct_product | WBCnstr00008863 | ||||||||
| WBCnstr00008864 | |||||||||
| WBCnstr00008865 | |||||||||
| WBCnstr00008866 | |||||||||
| WBCnstr00008867 | |||||||||
| WBCnstr00008868 | |||||||||
| WBCnstr00008869 | |||||||||
| WBCnstr00027105 | |||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (100) | |||||||||
| Interaction (57) | |||||||||
| Map_info | Map | II | Position | -0.501561 | |||||
| Positive | Positive_clone | F21H12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (18) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
