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WormBase Tree Display for Gene: WBGene00017778

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Name Class

WBGene00017778SMapS_parentSequenceF25B5
IdentityVersion3
NameCGC_namenono-1Person_evidenceWBPerson71
Sequence_nameF25B5.7
Molecular_name (12)
Other_namepsf-1Person_evidenceWBPerson71
CELE_F25B5.7Accession_evidenceNDBBX284603
Public_namenono-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:59WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
207 Jan 2008 15:11:50WBPerson2970Name_changeCGC_namepsf-1
310 Jul 2013 14:19:08WBPerson2970Name_changeCGC_namenono-1
Other_namepsf-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classnono
Allele (151)
StrainWBStrain00001597
WBStrain00036755
WBStrain00050861
RNASeq_FPKM (74)
GO_annotation00005952
00005953
00005954
00005955
00005956
00005957
00083993
00123109
00123110
Ortholog (54)
ParalogWBGene00007016Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00008549Caenorhabditis elegansFrom_analysisPanther
WBGene00017929Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00021901Caenorhabditis elegansFrom_analysisPanther
Structured_descriptionConcise_descriptionnono-1 encodes an ortholog of Drosophila NONA and of human NONO (OMIM:300084) and SFPQ (OMIM: 605199); fly NONA and human NONO are putative DNA- or RNA-binding proteins required for normal rhythmic behaviors; fly NONA is also required for embryonic development and visual behavior, and forms a complex with the mRNA export factor NXF1.Paper_evidenceWBPaper00028835
WBPaper00028838
Curator_confirmedWBPerson567
Date_last_updated06 Nov 2013 00:00:00
Automated_descriptionPredicted to enable RNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Located in nucleus. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); multiple myeloma; and syndromic X-linked intellectual disability 34. Is an ortholog of human PSPC1 (paraspeckle component 1) and SFPQ (splicing factor proline and glutamine rich).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0080685Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7871)
DOID:0060817Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7871)
DOID:0050700Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7871)
DOID:9538Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7871)
DOID:1059Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7871)
DOID:1936Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7871)
Molecular_infoCorresponding_CDSF25B5.7a
F25B5.7b
F25B5.7c
F25B5.7d
Corresponding_CDS_historyF25B5.7a:wp191
F25B5.7c:wp191
Corresponding_transcriptF25B5.7a.1
F25B5.7b.1
F25B5.7c.1
F25B5.7d.1
Other_sequence (46)
Associated_featureWBsf651091
WBsf651092
WBsf666942
WBsf992586
WBsf226744
Experimental_infoRNAi_resultWBRNAi00081958Inferred_automaticallyRNAi_primary
WBRNAi00031359Inferred_automaticallyRNAi_primary
WBRNAi00073050Inferred_automaticallyRNAi_primary
WBRNAi00045480Inferred_automaticallyRNAi_primary
WBRNAi00073049Inferred_automaticallyRNAi_primary
WBRNAi00005360Inferred_automaticallyRNAi_primary
WBRNAi00073048Inferred_automaticallyRNAi_primary
Expr_patternChronogram1155
Expr5852
Expr9482
Expr1028359
Expr1037641
Expr1149398
Expr2014354
Expr2032595
Drives_constructWBCnstr00002436
WBCnstr00027025
Construct_productWBCnstr00014047
WBCnstr00027025
Microarray_results (47)
Expression_cluster (88)
Interaction (59)
Map_infoMapIIIPosition-1.42973Error0.000405
PositivePositive_cloneF25B5Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00032289
WBPaper00038444
WBPaper00038491
WBPaper00041771
WBPaper00048643
WBPaper00052231
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene