WormBase Tree Display for Gene: WBGene00017904
expand all nodes | collapse all nodes | view schema
| WBGene00017904 | SMap | S_parent | Sequence | F28F5 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | lim-8 | Person_evidence | WBPerson54 | |||||
| WBPerson505 | |||||||||
| WBPerson545 | |||||||||
| Sequence_name | F28F5.3 | ||||||||
| Molecular_name | F28F5.3a | ||||||||
| F28F5.3a.1 | |||||||||
| CE29296 | |||||||||
| F28F5.3b | |||||||||
| CE29297 | |||||||||
| F28F5.3c | |||||||||
| CE30771 | |||||||||
| F28F5.3b.1 | |||||||||
| F28F5.3c.1 | |||||||||
| Other_name | tag-204 | Person_evidence | WBPerson201 | ||||||
| CELE_F28F5.3 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | lim-8 | ||||||||
| DB_info | Database | AceView | gene | 3H905 | |||||
| WormQTL | gene | WBGene00017904 | |||||||
| WormFlux | gene | WBGene00017904 | |||||||
| NDB | locus_tag | CELE_F28F5.3 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00017904|UniProtKB=Q8MNT0 | |||||||
| family | PTHR15551 | ||||||||
| NCBI | gene | 175952 | |||||||
| RefSeq | protein | NM_066083.8 | |||||||
| NM_171173.5 | |||||||||
| NM_066082.6 | |||||||||
| TREEFAM | TREEFAM_ID | TF315949 | |||||||
| TrEMBL | UniProtAcc | Q8MNT0 | |||||||
| Q95QI3 | |||||||||
| Q95QI2 | |||||||||
| UniProt_GCRP | UniProtAcc | Q8MNT0 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:30:59 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 02 Feb 2007 10:20:45 | WBPerson2970 | Name_change | CGC_name | tag-204 | ||||
| Other_name | gur-2 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | lim | ||||||||
| Allele (204) | |||||||||
| Strain | WBStrain00002013 | ||||||||
| WBStrain00003747 | |||||||||
| WBStrain00035954 | |||||||||
| WBStrain00055388 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00084263 | ||||||||
| 00084264 | |||||||||
| 00084265 | |||||||||
| 00084266 | |||||||||
| 00084267 | |||||||||
| 00084268 | |||||||||
| 00084269 | |||||||||
| Ortholog (40) | |||||||||
| Structured_description | Concise_description | lim-8 encodes proteins containing one PDZ and one LIM domain; in vitro binding and yeast two-hybrid assays indicate that LIM-8 can physically interact with myosin heavy chain A (MYO-3) as well as with UNC-96 and UNC-97, suggesting that LIM-8 is part of a structural component that links membrane attachment proteins to myosin thick filaments; lim-8(RNAi) in a hypersensitive rrf-3 background results in partially penetrant paralysis at mid-larval stages of development; a lim-8::gfp promoter fusion is expressed in pharyngeal and body wall muscles, as well as in vulva, spermathecae, anal sphincter and depressor muscles, head neurons, gonadal sheath, and the excretory canal; staining with LIM-8 antibodies reveals that in body wall muscle LIM-8 localizes, at least partially, to M-lines, around which myosin thick filaments are organized. | Paper_evidence | WBPaper00030924 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 27 Feb 2009 00:00:00 | ||||||||
| Automated_description | Enables protein domain specific binding activity. Predicted to be involved in positive regulation of stress fiber assembly and regulation of focal adhesion assembly. Located in M band. Expressed in excretory canal; head neurons; non-striated muscle; spermatheca; and vulva. Is an ortholog of human LIMCH1 (LIM and calponin homology domains 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F28F5.3a | |||||||
| F28F5.3b | |||||||||
| F28F5.3c | |||||||||
| Corresponding_transcript | F28F5.3a.1 | ||||||||
| F28F5.3b.1 | |||||||||
| F28F5.3c.1 | |||||||||
| Other_sequence (80) | |||||||||
| Associated_feature (19) | |||||||||
| Transcription_factor | WBTranscriptionFactor000439 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00014057 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00045844 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00045843 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00022342 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00005193 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00005494 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern (11) | |||||||||
| Drives_construct | WBCnstr00002796 | ||||||||
| WBCnstr00004182 | |||||||||
| WBCnstr00011917 | |||||||||
| WBCnstr00013256 | |||||||||
| WBCnstr00026930 | |||||||||
| Construct_product | WBCnstr00026930 | ||||||||
| Antibody | WBAntibody00001284 | ||||||||
| Microarray_results (39) | |||||||||
| Expression_cluster (188) | |||||||||
| Interaction (37) | |||||||||
| Map_info | Map | III | Position | -0.943352 | Error | 0.002564 | |||
| Positive | Positive_clone | F28F5 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4976 | |||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00026215 | ||||||||
| WBPaper00028592 | |||||||||
| WBPaper00030924 | |||||||||
| WBPaper00036199 | |||||||||
| WBPaper00038481 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00040494 | |||||||||
| WBPaper00042056 | |||||||||
| WBPaper00053597 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
